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LARC (MIP3a, Exodus) antibody

Reactivity: Rat IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN110549
  • Target
    LARC (MIP3a, Exodus)
    Reactivity
    Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Immunoprecipitation (IP), Western Blotting (WB)
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Storage
    4 °C
  • Baba, Imai, Nishimura, Kakizaki, Takagi, Hieshima, Nomiyama, Yoshie: "Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC." in: The Journal of biological chemistry, Vol. 272, Issue 23, pp. 14893-8, (1997) (PubMed).

    Rossi, Vicari, Franz-Bacon, McClanahan, Zlotnik: "Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 3, pp. 1033-6, (1997) (PubMed).

  • Target
    LARC (MIP3a, Exodus)
    Background
    LARC (liver and activation-regulated chemokine, MIP-3a , Exodus-1)1, 2, 3 is a 70-amino acid CC chemokine originally identified from human histiocytic lymphoma cell line U9371 and by sequence search of the EST database. This chemokine was mainly expressed in the liver and lung among various human tissues, and was also induced in several human cell lines. LARC is chemotactic for lymphocytes, weakly for neutrophils at high concentration, but not for monocytes. The LARC specific receptor has been identified as CCR64 .
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