Browse our CAND1 (CAND1) ELISA Kits

Full name:
Cullin-Associated and Neddylation-Dissociated 1 ELISA Kits (CAND1)
On www.antibodies-online.com are 4 Cullin-Associated and Neddylation-Dissociated 1 (CAND1) ELISA Kits from 1 different suppliers available. Additionally we are shipping CAND1 Antibodies (44) and CAND1 Proteins (3) and many more products for this protein. A total of 58 CAND1 products are currently listed.
Synonyms:
2310038O07Rik, 6330512O03Rik, AI195005, AI846556, ATCAND1, cand2, cullin-associated and neddylation dissociated, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1, D10Ertd516e, ETA2, fb78a05, HEMIVENATA, HVE, mKIAA0829, T8K22.14, T8K22_14, Tip120, Tip120A, Tp120a, wu:fb78a05, zgc:55729
list all ELISA KIts Gene Name GeneID UniProt
CAND1 71902 Q6ZQ38
CAND1 55832 Q86VP6
CAND1 117152 P97536

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More ELISA Kits for CAND1 Interaction Partners

Mouse (Murine) Cullin-Associated and Neddylation-Dissociated 1 (CAND1) interaction partners

  1. SCCRO recruits Ubc12 approximately NEDD8 to the CAND1-Cul1-ROC1 complex but that this is not sufficient to dissociate or overcome the inhibitory effects of CAND1 on cullin neddylation

Human Cullin-Associated and Neddylation-Dissociated 1 (CAND1) interaction partners

  1. Data show that the differentiation of LiSa-2 preadipocytes is associated with an increase of cullin-associated and neddylation-dissociated 1 (CAND1), COP9 (show COPS8 ELISA Kits) signalosome (CSN), neddylated cullin 3 (Cul3 (show CUL3 ELISA Kits)) and the BTB protein Keap1 (show KEAP1 ELISA Kits).

  2. The Epstein-Barr virus protein BPLF1, is targeted to cullin-RING ubiquitin ligases (CRLs) via the interaction of the conserved helix-2 with helix-23 of cullins, at a site involved in electrostatic interaction with CAND1.

  3. We demonstrate that the accumulation of p27 (show PAK2 ELISA Kits) is associated with an increase of CAND1 and a decrease of Skp2 during adipogenesis of human LiSa-2 preadipocytes. CAND1 knockdown reduces p27 (show PAK2 ELISA Kits) and blocks adipogenesis.

  4. Study shows that Cand1 can unambiguously stimulate SCF (show KITLG ELISA Kits) activity in vitro by enabling an F box protein (show FBXW10 ELISA Kits)-Skp1 (show SKP1 ELISA Kits) complex to access Cul1 (show CUL1 ELISA Kits) that was previously occupied by a different F box protein (show FBXW10 ELISA Kits)-Skp1 (show SKP1 ELISA Kits) complex, and that Cand1 promotes assembly in vivo of new F box proteins with pre-existing Cul1 (show CUL1 ELISA Kits) molecules.

  5. CAND1 promotes PLK4 (show PLK4 ELISA Kits)-mediated centriole overduplication and is frequently disrupted in prostate cancer.

  6. COMMD1 (show COMMD1 ELISA Kits) (copper metabolism MURR1 (show COMMD1 ELISA Kits) domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.

  7. CAND1 does not function by sequestering cullins in vivo to prevent substrate receptor autoubiquitination and is likely to regulate cullin RING ligase activity via alternative mechanisms

  8. miR (show MLXIP ELISA Kits)-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression.

  9. selectively binds to unneddylated CUL1 (show CUL1 ELISA Kits) and is dissociated by CUL1 (show CUL1 ELISA Kits) neddylation

  10. binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex

Arabidopsis thaliana Cullin-Associated and Neddylation-Dissociated 1 (CAND1) interaction partners

  1. HVE/CAND1 gene acts upstream of ATHB-8 at least in higher order veins, in a pathway that involves AXR1, but not LOP1, PIN1, CVP1 or CVP2.

  2. The disruption of the CAND1-CUL1 interaction results in an increased abundance of assembled SCF(TIR1) complex; stabilization of the CAND1-CUL1 interaction diminishes SCF(TIR1) complex abundance.

CAND1 Antigen Profile

Antigen Summary

Enhances transcription from various types of promoters. Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins (By similarity).

Alternative names and synonyms associated with CAND1

  • cullin-associated and neddylation-dissociated 1 (CAND1) Elisa Kit
  • cullin-associated and neddylation-dissociated 1 (cand1) Elisa Kit
  • cullin associated and neddylation disassociated 1 (Cand1) Elisa Kit
  • cullin-associated and neddylation-dissociated 1 (Cand1) Elisa Kit
  • cullin-associated NEDD8-dissociated protein 1 (CAND1) Elisa Kit
  • 2310038O07Rik Elisa Kit
  • 6330512O03Rik Elisa Kit
  • AI195005 Elisa Kit
  • AI846556 Elisa Kit
  • ATCAND1 Elisa Kit
  • cand2 Elisa Kit
  • cullin-associated and neddylation dissociated Elisa Kit
  • CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 Elisa Kit
  • D10Ertd516e Elisa Kit
  • ETA2 Elisa Kit
  • fb78a05 Elisa Kit
  • HEMIVENATA Elisa Kit
  • HVE Elisa Kit
  • mKIAA0829 Elisa Kit
  • T8K22.14 Elisa Kit
  • T8K22_14 Elisa Kit
  • Tip120 Elisa Kit
  • Tip120A Elisa Kit
  • Tp120a Elisa Kit
  • wu:fb78a05 Elisa Kit
  • zgc:55729 Elisa Kit

Protein level used designations for CAND1

cullin-associated and neddylation-dissociated 1 , cullin-associated and neddylation-dissociated 2 (putative) , TIP120 protein , cullin-associated NEDD8-dissociated protein 1 , cullin-associated and neddylation-dissociated protein 1 , p120 CAND1 , cullin-associated NEDD8-dissociated protein 1-like , TBP-interacting protein , TBP interacting protein , TBP-interacting protein 120A , TBP-interacting protein of 120 kDa A , TBP-interacting protein TIP120A , cullin associated and neddylation disassociated 1

GENE ID SPECIES
417837 Gallus gallus
447973 Xenopus (Silurana) tropicalis
452060 Pan troglodytes
100159824 Acyrthosiphon pisum
100173509 Pongo abelii
100177977 Ciona intestinalis
100202560 Hydra magnipapillata
100347974 Oryctolagus cuniculus
100386203 Callithrix jacchus
100485277 Xenopus (Silurana) tropicalis
100543082 Meleagris gallopavo
71902 Mus musculus
55832 Homo sapiens
117152 Rattus norvegicus
443799 Xenopus laevis
406806 Danio rerio
474437 Canis lupus familiaris
538086 Bos taurus
814786 Arabidopsis thaliana
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