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Disease causing mutations in inverted formin 2 (show INF2 Proteins) regulate its binding to G-actin (show ACTB Proteins), F-actin capping protein (CapZ (show CAPZB Proteins) alpha-1) and profilin 2 (show PFN2 Proteins).
mDia1 displaced from the barbed end by CapZ Actin Capping Protein can randomly slide along the actin filament and later return.
The present study suggests that CAPZA1 could be a marker of good prognosis in gastric cancer and shows that CAPZA1 is associated with decreased cancer cell migration and invasion.
V-1, a protein expressed transiently during murine cerebellar development, regulates actin polymerization via interaction with capping protein
Cd2 antigen (show CD2 Proteins) is linked to this protein via CMS (show Cd2ap Proteins) and CIN85 (show SH3KBP1 Proteins).
CKIP-1 (show PLEKHO1 Proteins) has a role in cell morphology that depends on its interaction with actin-capping protein (show TMOD4 Proteins)
Damaging exercise induced the expression of capZalpha, MCIP1 (show RCAN1 Proteins), CARP1, DNAJB2 (show DNAJB2 Proteins), c-myc (show MYC Proteins), and junD (show JUND Proteins), each of which are likely involved in skeletal muscle growth, remodeling, and stress management.
Actin-capping protein is a novel regulator of microtubule stability that functions by antagonizing mDia1 activity toward actin filaments.
Mouse homolog of the adaptor protein CARMIL (mCARMIL) binds CP with high affinity and decreases its affinity for the barbed end
CapZ is an important component in anchoring PKC-beta(II (show PLCb2 Proteins)) at the myofilaments, and for mediating the effects of PKC-beta(II (show PLCb2 Proteins)) on myofilament function
actin-capping protein (show TMOD4 Proteins) binds to the filament barbed end of myotrophin (show MTPN Proteins)/V-1
CKIP-1 has a role in cell morphology that depends on its interaction with actin-capping protein (show TMOD4 Proteins)
Results demonstrate myofilament regulation by protein phosphatase type 1 alpha and CapZ, and support the concept that cardiac Z-discs are vital components in intracellular signalling.
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.
F-actin-capping protein subunit alpha-1
, capping protein (actin filament) muscle Z-line, alpha 1
, F-actin capping protein alpha-1 subunit
, scapping protein (actin filament) muscle Z-line, alpha 1b
, actin-capping protein (CapZ 36/32) alpha subunit
, beta-actinin subunit I
, capZ 36/32
, Cap Z
, capZ alpha-1
, capping protein alpha 1
, CapZ alpha-1
, actin-binding protein chain A
, nuclear actin-binding protein chain a
, CP alpha1
, F-actin capping protein alpha 1 subunit