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Mouse (Murine) CCL21 ELISA Kit for Sandwich ELISA - ABIN625110
Said, Frierson, Sanchez-Carbayo, Brekken, Theodorescu: Loss of SPARC in bladder cancer enhances carcinogenesis and progression. in The Journal of clinical investigation 2013
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Results provide evidence for an association between an increase level of CCL21 and IP-10 (show CXCL10 ELISA Kits) in the blood and pulmonary involvement in systemic lupus erythematosus patients.
Gata1 (show GATA1 ELISA Kits)-KO(DC) DCs have reduced polysialic acid levels on their surface, which is a known determinant for the proper migration of DCs toward CCL21.
CCL21 and CXCL13 (show CXCL13 ELISA Kits) levels are increased in the minor salivary glands of patients with Sjogren's syndrome.
Deletion of this extended C-terminus reduces CCL21's affinity for heparin and transferring the CCL21 C-terminus to CCL19 (show CCL19 ELISA Kits) enhances heparin binding mainly through non-specific, electrostatic interactions
CCL21/CCR7 (show CCR7 ELISA Kits) interaction contributes to the time-dependent proliferation of PTC (show F9 ELISA Kits) cells by upregulating cyclin A (show CCNA2 ELISA Kits), cyclin B1 (show CCNB1 ELISA Kits) and cyclin-dependent kinase 1 (CDK1 (show CDK1 ELISA Kits)) expression via the extracellular signal-regulated kinase (ERK (show EPHB2 ELISA Kits)) pathway associated with iodine.
CCL21 can facilitate chemoresistance and stem cell property of colorectal cancer cells via the upregulation of P-gp (show ABCB4 ELISA Kits), Bmi-1 (show BMI1 ELISA Kits), Nanog (show NANOG ELISA Kits), and OCT-4 (show POU5F1 ELISA Kits) through AKT (show AKT1 ELISA Kits)/GSK-3beta (show GSK3b ELISA Kits)/Snail (show SNAI1 ELISA Kits) signals.
CCL21/CCR7 (show CCR7 ELISA Kits) induce VEGF-D (show Figf ELISA Kits) up-regulation and promote lymphangiogenesis via ERK (show EPHB2 ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway in lung cancer.
Our findings suggested that MUC1 (show MUC1 ELISA Kits) plays an important role in CCL21-CCR7 (show CCR7 ELISA Kits)-induced lymphatic metastasis and may serve as a therapeutic target in esophageal squamous cell carcinoma .
TGF-beta1 (show TGFB1 ELISA Kits) promoted CCL21 expression in lymphatic endothelial cells. CCL21 acted in a paracrine fashion to mediate chemotactic migration of EMT (show ITK ELISA Kits) cells toward lymphatic endothelial cells.
The chemotactic interaction between CCR7 (show CCR7 ELISA Kits) and its ligand, CCL21, may be a critical event during progression in pancreatic cancer
the CCR7 (show CCR7 ELISA Kits)/CCL21 signaling pathway leading to T lymphocyte migration on fibronectin (show FN1 ELISA Kits) is a beta1 integrin-dependent pathway involving transient ERK1/2 (show MAPK1/3 ELISA Kits) phosphorylation, which is modulated by PLCgamma1 (show PLCG1 ELISA Kits)
Data suggest that lymphotoxin (show LTB ELISA Kits)-dependent and -independent regulation of CC chemokine ligand 21-b and -c plays a role in balancing the central and peripheral immune responses between lymphoid and nonlymphoid tissues.
CCL21 and, to a lesser extent, CCL19 (show CCL19 ELISA Kits) play significant roles in the distinctive localization of marginal zone macrophages within the splenic marginal zone.
CCL21 and 5'-Nase may be involved in the interaction between infiltrating cells and lymphatic vessels to induce the functional changes of lymphatic endothelial cells during insulitic and diabetic development
CXCL9 (show CXCL9 ELISA Kits) has a role in graft rejection in the absence of CCL19 (show CCL19 ELISA Kits) and CCL21
T-cell defects in the nasal-associated lymphoid tissue of lymphotoxin (show LTB ELISA Kits)(-/-) mice can be attributed to the impaired expression of CCL21.
alpha-GalCer-loaded dendritic cells expressing tumor-associated antigen along with SLC can stimulate multiple subsets of effector cells to induce a potent therapeutic effect against peritoneally disseminated tumor cells.
following Leishmania donovani infection of mice, the migration of splenic DC is regulated by the CCR7 (show CCR7 ELISA Kits) ligands CCL19 (show CCL19 ELISA Kits)/CCL21
Results suggest that CCR7 (show CCR7 ELISA Kits)-positive fibrocytes infiltrate the kidney via CCL21-positive vessels, thereby contributing to the pathogenesis of renal fibrosis.
The presence of CCL21 during the in vitro stimulation of CD4 (show CD4 ELISA Kits)+ T cells with anti-CD3 (show CD3E ELISA Kits) plus anti-CD28 (show CD28 ELISA Kits) significantly enhanced in vitro AICD induction of the restimulated T cells, partially through enhancing expression of Fas ligand (show FASL ELISA Kits).
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
C-C motif chemokine 21
, CC chemokine ligand 21
, putative CCL21 chemokine
, small inducible cytokine A21
, small inducible cytokine A24
, Efficient Chemoattractant for Lymphocytes
, beta chemokine exodus-2
, secondary lymphoid tissue chemokine
, small inducible cytokine subfamily A (Cys-Cys), member 21
, chemokine CCL21/6CKINE
, small-inducible cytokine A21
, C-C motif chemokine 21b
, C-C motif chemokine 21c
, Small-inducible cytokine A21b
, beta-chemokine exodus-2
, small inducible cytokine A21c
, small-inducible cytokine A21c
, thymus-derived chemotactic agent 4