Browse our anti-Carboxypeptidase B2 (Plasma) (CPB2) Antibodies

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anti-Carboxypeptidase B2 (Plasma) Antibodies (CPB2)
On www.antibodies-online.com are 179 Carboxypeptidase B2 (Plasma) (CPB2) Antibodies from 21 different suppliers available. Additionally we are shipping Carboxypeptidase B2 (Plasma) Kits (55) and Carboxypeptidase B2 (Plasma) Proteins (26) and many more products for this protein. A total of 271 Carboxypeptidase B2 (Plasma) products are currently listed.
Synonyms:
1110032P04Rik, 1700120C01Rik, 4930405E17Rik, AI255929, AI325129, Cappb1, CPB1, CPB2, CPbeat2, CPbeta1, CPbeta2, CPR, Cpu, pCPB, TAFI
list all antibodies Gene Name GeneID UniProt
CPB2 12345 P47757
CPB2 1361  
CPB2 113936 Q9EQV9

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Most Popular Reactivities for anti-Carboxypeptidase B2 (Plasma) (CPB2) Antibodies

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Top referenced anti-Carboxypeptidase B2 (Plasma) Antibodies

  1. Human Polyclonal CPB2 Primary Antibody for ICC, IF - ABIN4287866 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

  2. Human Polyclonal CPB2 Primary Antibody for EIA, WB - ABIN452866 : Valnickova, Thogersen, Christensen, Chu, Pizzo, Enghild: Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein. in The Journal of biological chemistry 1996 (PubMed)

  3. Dog (Canine) Polyclonal CPB2 Primary Antibody for WB - ABIN2781326 : Ricart, Ramón, Vayá, España, Santaolaria, Todolí, Castelló, Fontcuberta, Estellés: Fibrinolytic inhibitor levels and polymorphisms in Behçet disease and their association with thrombosis. in British journal of haematology 2008 (PubMed)

More Antibodies against Carboxypeptidase B2 (Plasma) Interaction Partners

Mouse (Murine) Carboxypeptidase B2 (Plasma) (CPB2) interaction partners

  1. Cpb2-deficient mice had decreased pneumococcal meningitis mortality and attenuated cytokine levels and bacterial outgrowth in the syst (show SET Antibodies)emic compartment but not in the brain (show CSF2 Antibodies)compartment, as compared with wild-type mice.

  2. with strain there was significant PKCepsilon (show PRKCE Antibodies) translocation to the Z-disc and co-localization with CapZbeta1 or alpha-actinin (show ACTN1 Antibodies), which was quantified on confocal images.

  3. Carboxypeptidase B2 deficiency reveals that complement C3a (show C3 Antibodies) limits infection and C5a exacerbates infection in a murine polymicrobial sepsis model.

  4. Combination of TAFI (show SET Antibodies)-I and a low dose of rtPA was not as effective as the standard dose of rtPA in treating thromboembolic stroke, while TAFI (show SET Antibodies) inhibition alone was not effective at all.

  5. Capping protein-beta (show CAPZB Antibodies) knockdown decreases filopodial length, alters filopodial shape, and reduces filopodial dynamics.

  6. In an induced osteoarthritis model, CPB2 knockout mice developed dramatically greater cartilage damage than did wild-type mice, had a greater number of osteophytes, and a greater degree of synovitis.

  7. TAFI (show SET Antibodies) deficiency results in accelerated fibrogenesis and increased liver damage in murine models of chronic and acute liver disease, which may be related to increased inflammation.

  8. Actin-capping protein is a novel regulator of microtubule stability that functions by antagonizing mDia1 activity toward actin filaments.

  9. This study suggested that increased expression of TrkB (show NTRK2 Antibodies) and Capzb2 accompanies adequate brain reserve in the initial stages of AD pathology.

  10. The unique NFkappaB site in the mouse CPB2 promoter is functional and mediates the upregulation of mouse CPB2 expression by TNFalpha (show TNF Antibodies).

Human Carboxypeptidase B2 (Plasma) (CPB2) interaction partners

  1. TAFIa elicited anti-angiogenic responses by endothelial cells: decreased endothelial cell proliferation, cell invasion, cell migration, tube formation, and collagen degradation. It decreased tube formation and proteolysis in endothelial cell culture grown alone and in co-culture with breast cancer cell lines. TAFIa inhibition increased secretion of matrix metalloprotease (show ADAM8 Antibodies) proenzymes by endothelial and breast cancer cells.

  2. Plasma levels of TAFI are elevated in patients with chronic thromboembolic pulmonary hypertension and are correlated with resistance to clot (show TXNDC17 Antibodies) lysis in those patients.

  3. R12 (show GPR17 Antibodies) is a critical residue for the activation of TAFI by thrombin (show F2 Antibodies)-thrombomodulin (show THBD Antibodies)

  4. Thrombin activatable fibrinolysis inhibitor, particularly its preoperative levels but also levels during the immediate postoperative period, may be key for understanding coagulopathy during liver transplantation, and it may have a role as predictor of increased mortality rates in the liver transplant population

  5. The results suggest that although the TAFI S438G>T polymorphism is not correlated with venous thrombosis risk in all genetic models of venous thrombosis, a trend toward a reduced risk still could be observed. (Meta-analysis)

  6. The results of the present study demonstrated that the CPB2 expression in patients with chronic hepatitis C was inversely correlated with several risk factors of hepatic fibrosis or steatosis, although ectopic CPB2 expression did not suppress the expression of fibrogenic or lipogenic genes.

  7. Protein C (show PROC Antibodies) and TAFI are concurrently activated in a thrombomoulin-dependent manner and do not compete for the thrombin (show F2 Antibodies)-TM complex, raising the possibility that they interact with distinct activation complexes.

  8. Acute myocardial infarction patients have higher plasma CPU levels and lower proCPU levels than controls. This finding indicates in vivo generation of functional active CPU in patients with AMI (show CFD Antibodies).

  9. Arg12-Glu28 and Cys383-Val401 in TAFI are involved in thrombomodulin (show THBD Antibodies)-mediated TAFI activation. Gly205-Asp232 is involved in binding to thrombin (show F2 Antibodies).

  10. CPB2 polymorphisms (reference sequences: rs1926447 and rs3742264) were related to systemic complications in bacterial meningitis. TAFI levels correlated positively with CSF (show CSF2 Antibodies) complement. rs1926447 (TT) was associated with higher levels of TAFI in CSF (show CSF2 Antibodies).

Cow (Bovine) Carboxypeptidase B2 (Plasma) (CPB2) interaction partners

  1. analysis of the crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) and description of the structural basis for its intrinsic activity and the short half-life of TAFIa

  2. Purified bovine TAFI activated in the presence of a proteinaceous inhibitor renders a stable enzyme-inhibitor complex.

  3. Findings presented here suggest that the properties of these two orthologous proteins are similar and that conclusions reached using the bovine TAFI may be extrapolated to the human TAFI protein.

Carboxypeptidase B2 (Plasma) (CPB2) Antigen Profile

Antigen Summary

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region.

Alternative names and synonyms associated with Carboxypeptidase B2 (Plasma) (CPB2)

  • capping protein (actin filament) muscle Z-line, beta (Capzb) antibody
  • carboxypeptidase B2 (plasma) (CPB2) antibody
  • carboxypeptidase B2 (plasma) (Cpb2) antibody
  • 1110032P04Rik antibody
  • 1700120C01Rik antibody
  • 4930405E17Rik antibody
  • AI255929 antibody
  • AI325129 antibody
  • Cappb1 antibody
  • CPB1 antibody
  • CPB2 antibody
  • CPbeat2 antibody
  • CPbeta1 antibody
  • CPbeta2 antibody
  • CPR antibody
  • Cpu antibody
  • pCPB antibody
  • TAFI antibody

Protein level used designations for CPB2

F-actin-capping protein subunit beta , capZ beta , capping protein beta 1 , carboxypeptidase B-like protein , carboxypeptidase B2 , carboxypeptidase B2 (plasma, carboxypeptidase U) , carboxypeptidase R , thrombin-activable fibrinolysis inhibitor , thrombin-activatable fibrinolysis inhibitor , carboxypeptidase U , CPR , CPU , TAFI , plasma carboxypeptidase B

GENE ID SPECIES
12345 Mus musculus
1361 Homo sapiens
56373 Mus musculus
608910 Canis lupus familiaris
113936 Rattus norvegicus
508222 Bos taurus
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