Browse our anti-Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) Antibodies

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anti-Junction Mediating and Regulatory Protein, P53 Cofactor Antibodies (JMY)
On www.antibodies-online.com are 64 Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) Antibodies from 14 different suppliers available. Additionally we are shipping Junction Mediating and Regulatory Protein, P53 Cofactor Proteins (4) and and many more products for this protein. A total of 74 Junction Mediating and Regulatory Protein, P53 Cofactor products are currently listed.
Synonyms:
WHDC1L3
list all antibodies Gene Name GeneID UniProt
JMY 133746 Q8N9B5
JMY 57748 Q9QXM1
JMY 528498  

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Top referenced anti-Junction Mediating and Regulatory Protein, P53 Cofactor Antibodies

  1. Human Polyclonal JMY Primary Antibody for WB - ABIN1881469 : Coutts, Weston, La Thangue: A transcription co-factor integrates cell adhesion and motility with the p53 response. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 5 references for 1881469

More Antibodies against Junction Mediating and Regulatory Protein, P53 Cofactor Interaction Partners

Human Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) interaction partners

  1. In autophagosomes, the integrity of the WH2 domains allows JMY to promote actin nucleation, which is required for efficient autophagosome formation.

  2. JMY was expressed in normal tissues and heterogeneously in different tumor types, with close correlation between cytoplasmic and nuclear expression.

  3. JARID1A, JMY, and PTGER4 polymorphisms are related to ankylosing spondylitis in Chinese Han patients.

  4. JMY is related to the severity of AS in Chinese Han patients.

  5. actin assembly regulates nuclear import of JMY in response to DNA damage.

  6. JMY is expressed at high levels in brain tissue, and in various cell lines JMY is predominantly cytoplasmic, with a minor fraction in the nucleus.

  7. results establish the interplay between JMY and HIF-1alpha (show HIF1A Antibodies) as a new mechanism that controls cell motility under hypoxic stress

  8. Data demonstrate a pathway that links the cytoskeleton with the p53 (show TP53 Antibodies) response, and further suggest that the ability of JMY to regulate actin and cadherin is instrumental in coordinating cell motility with the p53 (show TP53 Antibodies) response.

  9. JMY represents a new class of multifunctional actin assembly factor whose activity is regulated, at least in part, by sequestration in the nucleus.

Mouse (Murine) Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) interaction partners

  1. JMY drives vesicular trafficking in the trans-Golgi region and at ER-membrane contact sites, distinct from other Arp2 (show AICDA Antibodies)/3 activators involved in vesicle transport processes such as the related WHAMM (show WHAMM Antibodies) or WASH.

  2. Results of the present study show that the nucleation-promoting factors JMY and WAVE2 (show WASF2 Antibodies) are critical for cytokinesis during development of mouse embryos.

  3. JMY is required for spindle migration, asymmetric division and cytokinesis during mouse oocyte maturation.

  4. The protein and messenger RNA levels of JMY were decreased in aged oocytes, but the levels were normal in caffeine-treated aged oocytes.

  5. JMY is a modulator of neuritogenesis

  6. These results define a new functional relationship between the p53 (show TP53 Antibodies) cofactor JMY and Mdm2 (show MDM2 Antibodies), and indicate that transcription cofactors that facilitate p53 (show TP53 Antibodies) activity are important targets for Mdm2 (show MDM2 Antibodies) in suppressing the p53 (show TP53 Antibodies) response.

Junction Mediating and Regulatory Protein, P53 Cofactor (JMY) Antigen Profile

Antigen Summary

Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics.

Alternative names and synonyms associated with Junction Mediating and Regulatory Protein, P53 Cofactor (JMY)

  • junction mediating and regulatory protein, p53 cofactor (JMY) antibody
  • junction mediating and regulatory protein, p53 cofactor (jmy) antibody
  • junction-mediating and regulatory protein (Jmy) antibody
  • WHDC1L3 antibody

Protein level used designations for JMY

junction mediating and regulatory protein, p53 cofactor , junction-mediating and regulatory protein , junction-mediating and -regulatory protein , WAS protein homology region 2 domain containing 1-like 3 , p300 transcriptional cofactor JMY

GENE ID SPECIES
461784 Pan troglodytes
709502 Macaca mulatta
100019728 Monodelphis domestica
100127594 Xenopus (Silurana) tropicalis
100228341 Taeniopygia guttata
133746 Homo sapiens
427182 Gallus gallus
610323 Canis lupus familiaris
528498 Bos taurus
57748 Mus musculus
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