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RAS P21 Protein Activator (GTPase Activating Protein) 1 ELISA Kits (RASA1)
On www.antibodies-online.com are 4 RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) ELISA Kits from 2 different suppliers available. Additionally we are shipping RASA1 Antibodies (103) and RASA1 Proteins (5) and many more products for this protein. A total of 118 RASA1 products are currently listed.
Synonyms:
CG9209, CM-AVM, CMAVM, D-RasGAP, Dmel\\CG9209, Gap, GAPX, p120GAP, p120RASGAP, PKWS, RAS-GAP, Rasa, RASGAP
list all ELISA KIts Gene Name GeneID UniProt
RASA1 5921 P20936
RASA1 25676 P50904
RASA1 218397  

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More ELISA Kits for RASA1 Interaction Partners

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. QKI-5 (show QKI ELISA Kits) stabilized RASA1 mRNA via directly binding to the QKI (show QKI ELISA Kits) response element region of RASA1, which in turn prevented the activation of the Ras-MAPK (show MAPK1 ELISA Kits) signaling pathway, suppressed cellular proliferation and induced cell cycle arrest.

  2. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  3. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  4. PTP1B (show PTPN1 ELISA Kits) dephosphorylates PITX1 (show PITX1 ELISA Kits) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  5. Data suggest that, in response to netrin-1 (show NTN1 ELISA Kits)/netrin receptor (DCC (show DCC ELISA Kits)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (show SRC ELISA Kits) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  6. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  7. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (show GNAQ ELISA Kits) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

  8. Data showed that hypoxia regulated the expression of miR (show MLXIP ELISA Kits)-182 and RASA1 to promote HCC (show FAM126A ELISA Kits) angiogenesis.

  9. p120RasGAP shields Akt (show AKT1 ELISA Kits) from deactivating phosphatases in FGF1 (show FGF1 ELISA Kits) signaling, but loses this ability once cleaved by caspase-3 (show CASP3 ELISA Kits).

  10. Capillary malformation-arteriovenous malformation syndrome (CM-AVM) is an autosomal dominant disorder caused by RASA1 mutations.

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. The data suggest that nitrosylation of H-Ras (show HRAS ELISA Kits) rearranges the adsorptive potential and intrinsic GTPase (show RACGAP1 ELISA Kits) activity of H-Ras (show HRAS ELISA Kits) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Double-deficient RASA1-neurofibromin 1 (show NF1 ELISA Kits) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (show NOTCH1 ELISA Kits) gene.

  2. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  3. Regulation of Rasa1 translation by miR (show MLXIP ELISA Kits)-132 was seen in severed axons, demonstrating local function within the axon.

  4. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  5. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 GTPase activating protein 1 (RASA1)

  6. 14-3-3 (show YWHAQ ELISA Kits) negatively regulates the RGC downstream of the PI3-kinase (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway

  7. Caspase-3 (show CASP3 ELISA Kits) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (show AKT1 ELISA Kits).

  8. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

  9. Ca2 (show CA2 ELISA Kits)+-dependent monomer and dimer formation switches CAPRI (show RASA4 ELISA Kits) Protein between Ras GTPase-activating protein (GAP) and RapGAP (show RAP1GAP ELISA Kits) activities

  10. statins inhibit GGPP biosynthesis in the mevalonate pathway, and then inhibit signal transduction in the Ras/ERK (show EPHB2 ELISA Kits) and Ras/Akt (show AKT1 ELISA Kits) pathways, thereby inhibiting bFGF (show FGF2 ELISA Kits), HGF (show HGF ELISA Kits), TGF-beta (show TGFB1 ELISA Kits) expression

RASA1 Antigen Profile

Antigen Summary

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Alternative names and synonyms associated with RASA1

  • vacuolar peduncle (vap) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) Elisa Kit
  • RAS p21 protein activator 1 (Rasa1) Elisa Kit
  • CG9209 Elisa Kit
  • CM-AVM Elisa Kit
  • CMAVM Elisa Kit
  • D-RasGAP Elisa Kit
  • Dmel\\CG9209 Elisa Kit
  • Gap Elisa Kit
  • GAPX Elisa Kit
  • p120GAP Elisa Kit
  • p120RASGAP Elisa Kit
  • PKWS Elisa Kit
  • RAS-GAP Elisa Kit
  • Rasa Elisa Kit
  • RASGAP Elisa Kit

Protein level used designations for RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

GENE ID SPECIES
32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
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