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High expression of thymosin beta 10 is associated with hepatocellular carcinoma.
High expression levels of TMSB10 correlated with lymphatic metasttases in papillary thyroid carcinoma, especially in the central neck region.
Tbeta10 human recombinant proteins promoted the expression of VEGF-C (show VEGFC ELISA Kits) by activating AKT (show AKT1 ELISA Kits) phosphorylation in lung cancer cell lines.
Regarding HCC (show FAM126A ELISA Kits), Tbeta4 reactivity was detected in 7/23 cases (30%) and Tbeta10 reactivity in 22/23 (97%) cases analyzed, adding HCC (show FAM126A ELISA Kits) to human cancers that express these beta-thymosins.
Low expression of Tbeta10 is associated with metastatic phenotype of CCA (show FBN2 ELISA Kits) in vitro and in vivo.
The results show, for the first time, a strong expression of thymosin beta 10 in the human salivary glands during the initial phases of the physiological development, present at the 13th week of gestation, and suggesting a role for the peptide in the salivary glands' organogenesis.
Thymosin beta10 expression driven by the human TERT (show TERT ELISA Kits) promoter induces ovarian cancer-specific apoptosis through ROS (show ROS1 ELISA Kits) production.
Amplification of thymosin beta 10 is associated with metastatic and aggressive papillary thyroid carcinomas.
TB10 plays a critical role in the regulation of anchorage-independent growth and assembly of actin filaments.
Introduction of E-Tmod cDNA into a tumor cell line reverses TB10 mediated apoptosis and restored actin architectures.
TMSB4 (show TMSB4X ELISA Kits) and/or TMSB10 ovarian expression patterns suggest that these two thymosins may be involved in cumulus modifications during maturation.
We found an increased expression of thymosin beta-10 mRNA in thyroid carcinomas, especially in anaplastic carcinomas.
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
thymosin beta 10
, migration-inducing gene 12
, migration-inducing protein 12
, thymosin beta-10
, thymosin beta-9
, thymosin, beta 10
, prothymosin beta 10