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Browse our Tropomyosin 1 (Alpha) (TPM1) ELISA Kits

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Tropomyosin 1 (Alpha) ELISA Kits (TPM1)
On www.antibodies-online.com are 2 Tropomyosin 1 (Alpha) (TPM1) ELISA Kits from 2 different suppliers available. Additionally we are shipping Tropomyosin 1 (Alpha) Antibodies (41) and Tropomyosin 1 (Alpha) Proteins (34) and many more products for this protein. A total of 82 Tropomyosin 1 (Alpha) products are currently listed.
Synonyms:
AA986836, AI854628, alpha-fTM, Alpha-tm, alpha-tropomyosin, C15orf13, CH1, CMD1Y, CMH3, fb37a09, HTM-alpha, MGC84844, tm, TM2, Tm3, Tm7, Tma2, Tmpa, Tmsa, Tpm-1, tpm1, TPMA, wu:fb37a09
list all ELISA KIts Gene Name GeneID UniProt
TPM1 7168 P09493
Mouse TPM1 TPM1 22003 P58771
Rat TPM1 TPM1 24851 P04692

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More ELISA Kits for Tropomyosin 1 (Alpha) Interaction Partners

Rabbit Tropomyosin 1 (Alpha) (TPM1) interaction partners

  1. The results indicate that cross-linking significantly affects properties of Tpm (show TPMT ELISA Kits) and actin-myosin interaction and can explain, at least partly, the role of the interchain disulfide cross-linking of cardiac Tpm (show TPMT ELISA Kits) in human heart diseases.

  2. altered TM-actin contacts destabilized the thin filament and affected the actin-myosin interactions

  3. analysis of the thin filament associated with the R167H and K168E substitutions in tropomyosin (show TPM2 ELISA Kits) Tpm1.1

  4. We propose that TR100 acts to compromise the integrity of Tpm cables rather than prevent overlap complex formation. Our data suggests that TR100 is incorporated into the growing actin-Tpm co-polymer given that its effects cannot be observed on pre-formed Tpm3.1/actin filaments

  5. Maximal Ca(2 (show CA2 ELISA Kits)+) activated force was the same in alphaalphaTm versus betabetaTm myofibrils, but betabetaTm myofibrils showed a marked slowing of relaxation and an impairment of regulation under resting conditions

  6. Tmod1 (show TMOD1 ELISA Kits) and Tmod3 (show TMOD3 ELISA Kits) showed somewhat different tropomyosin (show TPM2 ELISA Kits)-binding site utilization.

  7. Thermal denaturation of rabbit cardiac alpha,alpha-tropomyosin is monitored at neutral pH and compared to shark tropomyosin (show TPM2 ELISA Kits), showing that amino acid substitutions predicted to be unfavorable in one temperature regime are desirable in another.

  8. The rotational motion of a spin label covalently bound to the side chain of a cysteine genetically incorporated into rabbit skeletal muscle tropomyosin (show TPM2 ELISA Kits), was measured.

  9. a computational search assessing electrostatic interactions for multiple azimuthal locations, z-positions, and pseudo-rotations of tropomyosin on F-actin was performed.

Human Tropomyosin 1 (Alpha) (TPM1) interaction partners

  1. Data indicate that various hypertrophic cardiomyopathy (HCM) mutations can differently affect the structural and functional properties of tropomyosin (show TPM2 ELISA Kits) (Tpm (show TPMT ELISA Kits)) and cause HCM by different molecular mechanisms.

  2. Promoter variants in HOXA9 (show HOXA9 ELISA Kits), TPM1, and TPM2 (show TPM2 ELISA Kits), alter promoter expression suggesting that they have a functional role in clubfoot.

  3. The TPM1 mutations D175N and E180G increased the sliding velocity and its calcium sensitivity of the actin-myosin Interaction, while mutation E40K reduced both these parameters.

  4. No association was observed between the remaining three markers (rs11071720, rs3803499, and rs12148828) and NSOC as well as its subgroups. TPM1 polymorphisms might contribute to the etiology ofnonsyndromic orofacial clefts (NSOC), , and more emphasis should be placed on TPM1 during craniofacial development

  5. We propose that TR100 acts to compromise the integrity of Tpm cables rather than prevent overlap complex formation. Our data suggests that TR100 is incorporated into the growing actin-Tpm co-polymer given that its effects cannot be observed on pre-formed Tpm3.1/actin filaments

  6. Structural stabilization of F-actin, by overexpression of tropomyosin-1, preserves cell to cell interactions through the attenuation of cortical actin organization into thin fibers and thus protects these cells against oxidative stress-induced degradation of actin cytoskeleton and cell death.

  7. The TPM1 (rs1071646) and TNNT2 (show TNNT2 ELISA Kits) (rs3729547) gene variants might represent risk factors for patients with dilated cardiomyopathy in the Kazakh population.

  8. The mutation reduced binding affinity for both Lmod2 (show LMOD2 ELISA Kits) and Tmod1 (show TMOD1 ELISA Kits). The effect of the K15N mutation on Tpm1.1 binding to Lmod2 (show LMOD2 ELISA Kits) and Tmod1 (show TMOD1 ELISA Kits) provides a molecular rationale for the development of familial dilated cardiomyopathies .

  9. Data confirm that the substitutions of the Tpm1 residues G126 and D137 with the canonical ones, Arg and Leu, respectively, increase the stiffness of the Tpm (show TPMT ELISA Kits) coiled-coil

  10. these results indicate that TPM1 may be one mechanism underlying radiation resistance, and TPM1 may be a potential target for overcoming the radiation resistance in glioma.

Pig (Porcine) Tropomyosin 1 (Alpha) (TPM1) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Cow (Bovine) Tropomyosin 1 (Alpha) (TPM1) interaction partners

  1. The tendency of smooth muscle tropomyosin to form semi-rigid polymers with continuous and undampened rigidity may compensate for the lack of troponin-based structural support in smooth muscles.

  2. Deletion of regions 2-3 in tropomyosin (show TPM2 ELISA Kits) alpha resulted in an 60 % decrease in both isometric tension and stiffness of tropomyosin (show TPM2 ELISA Kits)-reconstituted myocardium.

  3. Tropomyosin (show TPM2 ELISA Kits) is primarily responsible for the change in the kinetic constants of the elementary steps of the cross bridge cycle.

  4. Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules

Mouse (Murine) Tropomyosin 1 (Alpha) (TPM1) interaction partners

  1. The cMyBP-C hypertrophic cardiomyopathy variant L348P enhances thin filament activation through an increased shift in tropomyosin (show TPM2 ELISA Kits) position.

  2. three-dimensional structure of F-actin at a resolution of 3.7 A in complex with tropomyosin (show TPM2 ELISA Kits) at a resolution of 6.5 A, determined by electron cryomicroscopy

  3. data also identify a novel alphaTM1/Tmod1 (show TMOD1 ELISA Kits)-based pathway stabilizing F-actin at cell-cell junctions, which may be required for maintenance of cell shapes during embryonic cardiac morphogenesis (show XIRP1 ELISA Kits).

  4. This is the first study to demonstrate that decreasing phosphorylation of tropomyosin (show TPM2 ELISA Kits) can rescue a hypertrophic cardiomyopathic phenotype.

  5. Tropomyosin (show TPM2 ELISA Kits) dephosphorylation results in myocyte hypertrophy with increases in SERCA2a (show ATP2A2 ELISA Kits) expression.

  6. The results identify a novel mode of myofilament desensitization to Ca(2 (show CA2 ELISA Kits)+) associated with a DCM linked switch in TPM1-kappa.

  7. signaling by alpha-tropomyosin may have a role in familial hypertrophic cardiomyopathy

  8. A point mutation in alpha-TM causes a disease similar to familial hypertophic cardiomyopahy.

  9. PTB (show PTBP1 ELISA Kits) interacting protein raver1 (show RAVER1 ELISA Kits) regulates alpha-tropomyosin alternative splicing.

  10. the N terminus is a critical determinant of TM1 (show TPM2 ELISA Kits) functions, which in turn determines the organization of stress fibers.

Tropomyosin 1 (Alpha) (TPM1) Antigen Profile

Antigen Summary

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Alternative names and synonyms associated with Tropomyosin 1 (Alpha) (TPM1)

  • alpha-tropomyosin (LOC100125989) Elisa Kit
  • alpha-tropomyosin (tpma) Elisa Kit
  • tropomyosin (tm7) Elisa Kit
  • tropomyosin (Smp_044010.2) Elisa Kit
  • tropomyosin 1 (LOC732984) Elisa Kit
  • tropomyosin 1 (alpha) (TPM1) Elisa Kit
  • tropomyosin 1 (alpha) (tpm1) Elisa Kit
  • tropomyosin 1, alpha (Tpm1) Elisa Kit
  • AA986836 Elisa Kit
  • AI854628 Elisa Kit
  • alpha-fTM Elisa Kit
  • Alpha-tm Elisa Kit
  • alpha-tropomyosin Elisa Kit
  • C15orf13 Elisa Kit
  • CH1 Elisa Kit
  • CMD1Y Elisa Kit
  • CMH3 Elisa Kit
  • fb37a09 Elisa Kit
  • HTM-alpha Elisa Kit
  • MGC84844 Elisa Kit
  • tm Elisa Kit
  • TM2 Elisa Kit
  • Tm3 Elisa Kit
  • Tm7 Elisa Kit
  • Tma2 Elisa Kit
  • Tmpa Elisa Kit
  • Tmsa Elisa Kit
  • Tpm-1 Elisa Kit
  • tpm1 Elisa Kit
  • TPMA Elisa Kit
  • wu:fb37a09 Elisa Kit

Protein level used designations for Tropomyosin 1 (Alpha) (TPM1) ELISA Kits

tropomyosin alpha-1 chain , tropomyosin , Tropomyosin-1 alpha chain , tropomyosin-1 , alpha-tropomyosin 1 , alpha-tropomyosin 2 , alpha-tropomyosin of skeletal fast muscle , tropomyosin (CTm4) , tropomyosin (CTm7) , alpha-tropomyosin , cardiomyopathy, hypertrophic 3 , sarcomeric tropomyosin kappa , tropomyosin 1 (alpha) isoform 1 , tropomyosin 1 (alpha) isoform 2 , tropomyosin 1 (alpha) isoform 3 , tropomyosin 1 (alpha) isoform 4 , tropomyosin 1 (alpha) isoform 5 , tropomyosin 1 (alpha) isoform 6 , tropomyosin 1 (alpha) isoform 7 , tropomyosin 1 alpha chain , alpha-skeletal tropomyosin , alpha tropomyosin , hepatoma alpha tropomyosin , smooth muscle alpha-tropomyosin , striated muscle alpha-tropomyosin , tropomyosin 3 alpha

GENE ID SPECIES
100125989 Oryctolagus cuniculus
30324 Danio rerio
431788 Xenopus laevis
8350314 Schistosoma mansoni
732984 Bombyx mori
396366 Gallus gallus
7168 Homo sapiens
100037999 Sus scrofa
281544 Bos taurus
100189579 Xenopus laevis
478332 Canis lupus familiaris
22003 Mus musculus
24851 Rattus norvegicus
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