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Browse our anti-BCL11A (BCL11A) Antibodies

Full name:
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) Antibodies (BCL11A)
On www.antibodies-online.com are 148 B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) Antibodies from 21 different suppliers available. Additionally we are shipping BCL11A Kits (8) and BCL11A Proteins (6) and many more products for this protein. A total of 171 BCL11A products are currently listed.
Synonyms:
2810047E18Rik, BCL-11A, bcl11a, BCL11A-L, BCL11a-M, BCL11A-S, BCL11A-XL, CTIP1, D930021L15Rik, EVI9, Evi9a, Evi9b, Evi9c, HBFQTL5, mKIAA1809, wu:fi09f10, zgc:136898, ZNF856
list all antibodies Gene Name GeneID UniProt
BCL11A 14025 Q9QYE3
BCL11A 53335 Q9H165
BCL11A 305589  

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anti-Mouse (Murine) BCL11A Antibodies:

anti-Human BCL11A Antibodies:

anti-Rat (Rattus) BCL11A Antibodies:

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Top referenced anti-BCL11A Antibodies

  1. Human Monoclonal BCL11A Primary Antibody for WB - ABIN395972 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395972

  2. Human Polyclonal BCL11A Primary Antibody for EIA, WB - ABIN950622 : Nuinoon, Makarasara, Mushiroda, Setianingsih, Wahidiyat, Sripichai, Kumasaka, Takahashi, Svasti, Munkongdee, Mahasirimongkol, Peerapittayamongkol, Viprakasit, Kamatani, Winichagoon, Kubo, Nakamura, Fucharoen: A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E. in Human genetics 2010 (PubMed)
    Show all 2 references for ABIN950622

  3. Human Polyclonal BCL11A Primary Antibody for WB - ABIN653582 : Solovieff, Milton, Hartley, Sherva, Sebastiani, Dworkis, Klings, Farrer, Garrett, Ashley-Koch, Telen, Fucharoen, Ha, Li, Chui, Baldwin, Steinberg: Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster. in Blood 2010 (PubMed)
    Show all 2 references for ABIN653582

  4. Human Polyclonal BCL11A Primary Antibody for ChIP, FACS - ABIN4300809 : Xu, Sankaran, Ni, Menne, Puram, Kim, Orkin: Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6. in Genes & development 2010 (PubMed)
    Show all 2 references for ABIN4300809

  5. Human Polyclonal BCL11A Primary Antibody for IP, WB - ABIN153198 : Chen, Luo, Steinberg, Chui: BCL11A represses HBG transcription in K562 cells. in Blood cells, molecules & diseases 2009 (PubMed)

  6. Cow (Bovine) Polyclonal BCL11A Primary Antibody for IHC, WB - ABIN2781048 : Uda, Galanello, Sanna, Lettre, Sankaran, Chen, Usala, Busonero, Maschio, Albai, Piras, Sestu, Lai, Dei, Mulas, Crisponi, Naitza, Asunis, Deiana, Nagaraja, Perseu, Satta, Cipollina, Sollaino, Moi, Hirschhorn, Orkin, Abecasis, Schlessinger, Cao: Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against BCL11A Interaction Partners

Mouse (Murine) B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. data identify Ctip1 as a critical control over sensory cortex development

  2. Bcl11a haploinsufficiency in mice causes impaired cognition, abnormal social behavior, and microcephaly in accordance with the human phenotype

  3. deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice

  4. This study showed that the expression of Sema3c (show SEMA3C Antibodies) is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c (show SEMA3C Antibodies) transcription

  5. The results of this study support a role for CTIP1 on the specification of the Subcerebral Projection Neurons in layer 5 through the repression of TBR1 (show TBR1 Antibodies) and the promotion of CTIP2 (show BCL11B Antibodies) expression.

  6. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  7. BCL11A is an essential, lineage-specific factor that regulates plasmacytoid dendritic cell development, supporting a model wherein differentiation into pDCs represents a primed "default" pathway for common dendritic cell progenitors.

  8. Bcl11a controls Flt3 (show FLT3 Antibodies) expression in early hematopoietic progenitors and is required for pDC (show PDC Antibodies) development in vivo.

  9. Immunohistochemical staining of mouse brain showed strong expression of BCL11A in the cortical regions and also in the pyramidal cell layers in the CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies) regions of the hippocampus.

  10. data support an important role for the KLF1-BCL11A axis in erythroid maturation and developmental regulation of globin expression

Human B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. The BCL11A gene was found to be potentially targeted by 12 MicroRNAs that were up-regulated in Hereditary persistence of fetal hemoglobin deletion type-2 (HPFH-2) or in Sicilian deltabeta-thalassemia. A down-regulation of BCL11A gene expression in HPFH-2 was verified by quantitative polymerase chain reaction.

  2. The BCL11A protein is highly expressed in breast cancer and knock-down of BCL11A promotes the apoptosis of MDA-MB-231 cells.

  3. his study confirms that the T/C variant (rs11886868) of the BCL11A gene causing downregulation of BCL11A gene expression in adult erythroid precursors results in the induction of HbF and ameliorates the severity of a-thalassaemia as well as sickle cell anaemia.

  4. report of an intellectual disability syndrome caused by de novo heterozygous missense, nonsense, and frameshift mutations in BCL11A, encoding a transcription factor that is a putative member of the BAF (show BANF1 Antibodies) swi (show SMARCA1 Antibodies)/snf (show SNRPA Antibodies) chromatin-remodeling complex

  5. Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A and HMIP (show MIPEP Antibodies)-2 loci

  6. the association between modifier loci (beta-globin (show HBB Antibodies) gene cluster, HBS1L (show HBS1L Antibodies)-MYB (show MYB Antibodies) intergenic region and BCL11A) and Hb F levels in Chinese Zhuang beta-TI patients

  7. The combination of the genotypes GG and CT explains more phenotypic variance than the sum of the two BCL11A SNPs taken individually.

  8. our study suggests that FOXQ1 (show FOXQ1 Antibodies) regulates prostate cancer cell proliferation and apoptosis by regulating BCL11A/MDM2 (show MDM2 Antibodies) expression and indicates that FOXQ1 (show FOXQ1 Antibodies) may serve as a potential therapeutic target for prostate cancer.

  9. this study aimed to find the effect of these genetic modifiers, especially in the XmnI locus, rs11886868, rs766432 (BCL11A), and rs9399137 (HBS1L-MYB), among beta thalassemia (beta-thal) and Hemoglobin E/beta-thal patients in Indonesia.

  10. Extensive genetic analyses have validated BCL11A as a potent repressor of fetal hemoglobin (show HBB Antibodies) level. Studies of BCL11A exemplify how contextual gene regulation may often be the substrate for trait-associated common genetic variation

BCL11A Antigen Profile

Antigen Summary

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative names and synonyms associated with BCL11A

  • B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (bcl11a) antibody
  • B-cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) antibody
  • B-cell CLL/lymphoma 11Aa (bcl11aa) antibody
  • 2810047E18Rik antibody
  • BCL-11A antibody
  • bcl11a antibody
  • BCL11A-L antibody
  • BCL11a-M antibody
  • BCL11A-S antibody
  • BCL11A-XL antibody
  • CTIP1 antibody
  • D930021L15Rik antibody
  • EVI9 antibody
  • Evi9a antibody
  • Evi9b antibody
  • Evi9c antibody
  • HBFQTL5 antibody
  • mKIAA1809 antibody
  • wu:fi09f10 antibody
  • zgc:136898 antibody
  • ZNF856 antibody

Protein level used designations for BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein) , B-cell lymphoma/leukemia 11A , COUP-TF interacting protein 1 , COUP-TF-interacting protein 1 , EVI-9 , ecotropic viral integration site 9 protein , myeloid leukemia , B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 , BCL-11A , BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1 , C2H2-type zinc finger protein , ecotropic viral integration site 9 homolog , ecotropic viral integration site 9 protein homolog , zinc finger protein 856 , B-cell CLL/lymphoma 11A , bcl11a.1 , fi09f10

GENE ID SPECIES
14025 Mus musculus
53335 Homo sapiens
398877 Xenopus laevis
421199 Gallus gallus
481381 Canis lupus familiaris
538680 Bos taurus
305589 Rattus norvegicus
678650 Danio rerio
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