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B-Cell CLL/lymphoma 11A (Zinc Finger Protein) ELISA Kits (BCL11A)
On www.antibodies-online.com are 8 B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) ELISA Kits from 6 different suppliers available. Additionally we are shipping BCL11A Antibodies (149) and BCL11A Proteins (6) and many more products for this protein. A total of 172 BCL11A products are currently listed.
Synonyms:
2810047E18Rik, BCL-11A, bcl11a, BCL11A-L, BCL11a-M, BCL11A-S, BCL11A-XL, CTIP1, D930021L15Rik, EVI9, Evi9a, Evi9b, Evi9c, HBFQTL5, mKIAA1809, wu:fi09f10, zgc:136898, ZNF856
list all ELISA KIts Gene Name GeneID UniProt
BCL11A 14025 Q9QYE3
BCL11A 53335 Q9H165
Rat BCL11A BCL11A 305589  

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Mouse (Murine) B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Bcl11a enhancer-deleted mice, Bcl11a(Deltaenh), phenocopy the BCL11A-null state with respect to alterations of globin expression.

  2. data identify Ctip1 as a critical control over sensory cortex development

  3. Bcl11a haploinsufficiency in mice causes impaired cognition, abnormal social behavior, and microcephaly in accordance with the human phenotype

  4. deletion of Bcl11a alters the regulation of hematopoietic stem cell quiescence, self-renewal, and fate choice

  5. This study showed that the expression of Sema3c (show SEMA3C ELISA Kits) is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c (show SEMA3C ELISA Kits) transcription

  6. The results of this study support a role for CTIP1 on the specification of the Subcerebral Projection Neurons in layer 5 through the repression of TBR1 and the promotion of CTIP2 (show BCL11B ELISA Kits) expression.

  7. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  8. BCL11A is an essential, lineage-specific factor that regulates plasmacytoid dendritic cell development, supporting a model wherein differentiation into pDCs represents a primed "default" pathway for common dendritic cell progenitors.

  9. Bcl11a controls Flt3 (show FLT3 ELISA Kits) expression in early hematopoietic progenitors and is required for pDC (show PDC ELISA Kits) development in vivo.

  10. Immunohistochemical staining of mouse brain showed strong expression of BCL11A in the cortical regions and also in the pyramidal cell layers in the CA1 (show CA1 ELISA Kits) and CA3 (show CA3 ELISA Kits) regions of the hippocampus.

Human B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) interaction partners

  1. Ubiquitous knockdown of BCL11A in hematopoietic stem and progenitor cells impairs hematopoietic reconstitution after transplantation.

  2. BCL11A rs11886868 and rs4671393 genotype variations and correspondingly high BCL11A plasma levels are related to laryngeal squamous cell carcinoma, besides, differences in plasma levels and genotype distribution may be related to lymph node metastasis status and the stage of laryngeal squamous cell carcinoma.

  3. BCL11A may operate in transformation of CML from chronic to acute phase in some persons

  4. The BCL11A gene was found to be potentially targeted by 12 MicroRNAs that were up-regulated in Hereditary persistence of fetal hemoglobin deletion type-2 (HPFH-2) or in Sicilian deltabeta-thalassemia. A down-regulation of BCL11A gene expression in HPFH-2 was verified by quantitative polymerase chain reaction.

  5. The BCL11A protein is highly expressed in breast cancer and knock-down of BCL11A promotes the apoptosis of MDA-MB-231 cells.

  6. his study confirms that the T/C variant (rs11886868) of the BCL11A gene causing downregulation of BCL11A gene expression in adult erythroid precursors results in the induction of HbF and ameliorates the severity of a-thalassaemia as well as sickle cell anaemia.

  7. report of an intellectual disability syndrome caused by de novo heterozygous missense, nonsense, and frameshift mutations in BCL11A, encoding a transcription factor that is a putative member of the BAF (show BANF1 ELISA Kits) swi (show SMARCA1 ELISA Kits)/snf (show SNRPA ELISA Kits) chromatin-remodeling complex

  8. Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A and HMIP (show MIPEP ELISA Kits)-2 loci

  9. the association between modifier loci (beta-globin (show HBB ELISA Kits) gene cluster, HBS1L (show HBS1L ELISA Kits)-MYB (show MYB ELISA Kits) intergenic region and BCL11A) and Hb F levels in Chinese Zhuang beta-TI patients

  10. The combination of the genotypes GG and CT explains more phenotypic variance than the sum of the two BCL11A SNPs taken individually.

BCL11A Antigen Profile

Antigen Summary

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Alternative names and synonyms associated with BCL11A

  • B cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) Elisa Kit
  • B-cell CLL/lymphoma 11A (zinc finger protein) (BCL11A) Elisa Kit
  • B-cell CLL/lymphoma 11A (zinc finger protein) (bcl11a) Elisa Kit
  • B-cell CLL/lymphoma 11A (zinc finger protein) (Bcl11a) Elisa Kit
  • B-cell CLL/lymphoma 11Aa (bcl11aa) Elisa Kit
  • 2810047E18Rik Elisa Kit
  • BCL-11A Elisa Kit
  • bcl11a Elisa Kit
  • BCL11A-L Elisa Kit
  • BCL11a-M Elisa Kit
  • BCL11A-S Elisa Kit
  • BCL11A-XL Elisa Kit
  • CTIP1 Elisa Kit
  • D930021L15Rik Elisa Kit
  • EVI9 Elisa Kit
  • Evi9a Elisa Kit
  • Evi9b Elisa Kit
  • Evi9c Elisa Kit
  • HBFQTL5 Elisa Kit
  • mKIAA1809 Elisa Kit
  • wu:fi09f10 Elisa Kit
  • zgc:136898 Elisa Kit
  • ZNF856 Elisa Kit

Protein level used designations for BCL11A

B-cell CLL/lymphoma 11A (zinc finger protein) , B-cell lymphoma/leukemia 11A , COUP-TF interacting protein 1 , COUP-TF-interacting protein 1 , EVI-9 , ecotropic viral integration site 9 protein , myeloid leukemia , B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2 , BCL-11A , BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1 , C2H2-type zinc finger protein , ecotropic viral integration site 9 homolog , ecotropic viral integration site 9 protein homolog , zinc finger protein 856 , B-cell CLL/lymphoma 11A , bcl11a.1 , fi09f10

GENE ID SPECIES
14025 Mus musculus
53335 Homo sapiens
398877 Xenopus laevis
421199 Gallus gallus
481381 Canis lupus familiaris
538680 Bos taurus
305589 Rattus norvegicus
678650 Danio rerio
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