Browse our anti-Osteopontin (SPP1) Antibodies

Full name:
anti-Secreted phosphoprotein 1 Antibodies (SPP1)
On www.antibodies-online.com are 410 Secreted phosphoprotein 1 (SPP1) Antibodies from 36 different suppliers available. Additionally we are shipping Osteopontin Kits (120) and Osteopontin Proteins (53) and many more products for this protein. A total of 605 Osteopontin products are currently listed.
Synonyms:
2AR, AI463453, Apl-1, BNSP, Bsp, BSPI, Eta, ETA-1, OP, Opn, Opnl, OSP, Ric, SPP, Spp-1, SPP1, SPPase1, Spph1, zgc:111821

Most Popular Reactivities for anti-Osteopontin (SPP1) Antibodies

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anti-Human Osteopontin Antibodies:

anti-Mouse (Murine) Osteopontin Antibodies:

anti-Rat (Rattus) Osteopontin Antibodies:

All available anti-Osteopontin Antibodies

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Top referenced anti-Osteopontin Antibodies

  1. Human Monoclonal Osteopontin Primary Antibody for ICC, IF - ABIN259958 : Kon, Yokosaki, Maeda, Segawa, Horikoshi, Tsukagoshi, Rashid, Morimoto, Inobe, Shijubo, Chambers, Uede: Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences. in Journal of cellular biochemistry 2002 (PubMed)
    Show all 15 references for 259958

  2. Dog (Canine) Polyclonal Osteopontin Primary Antibody for EIA, IHC (p) - ABIN118005 : Yamasaki, Nair, Bhattacharya, Yamamoto, Kurazono, Takeda: Cryptic appearance of a new clone of Vibrio cholerae serogroup 01 biotype El Tor in Calcutta, India. in Microbiology and immunology 1997 (PubMed)
    Show all 12 references for 118005

  3. Human Polyclonal Osteopontin Primary Antibody for EIA, IHC (p) - ABIN191686 : Frosch, Barvencik, Lohmann, Viereck, Siggelkow, Breme, Dresing, Stürmer: Migration, matrix production and lamellar bone formation of human osteoblast-like cells in porous titanium implants. in Cells, tissues, organs 2002 (PubMed)
    Show all 3 references for 191686

  4. Human Polyclonal Osteopontin Primary Antibody for EIA, IF - ABIN953945 : Weber, Lett, Haubein: Osteopontin is a marker for cancer aggressiveness and patient survival. in British journal of cancer 2010 (PubMed)
    Show all 3 references for 953945

  5. Mouse (Murine) Polyclonal Osteopontin Primary Antibody for FACS - ABIN4895890 : Kuwahara, Suzuki, Tofukuji, Yamada, Kanoh, Matsumoto, Maruyama, Kometani, Kurosaki, Ohara, Nakayama, Yamashita: The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. in Nature communications 2014 (PubMed)

  6. Human Polyclonal Osteopontin Primary Antibody for FACS, IHC (p) - ABIN390469 : Agnihotri, Crawford, Haro, Matrisian, Havrda, Liaw: Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). in The Journal of biological chemistry 2001 (PubMed)

  7. Dog (Canine) Polyclonal Osteopontin Primary Antibody for WB - ABIN2774903 : Emani, Zhang, Guo, Guo, Kuo: RNA stability regulates differential expression of the metastasis protein, osteopontin, in hepatocellular cancer. in Surgery 2008 (PubMed)

  8. Cow (Bovine) Polyclonal Osteopontin Primary Antibody for IHC, WB - ABIN2774904 : Iwata, Awaya, Graf, Kahl, Torok-Storb: Human marrow stromal cells activate monocytes to secrete osteopontin, which down-regulates Notch1 gene expression in CD34+ cells. in Blood 2004 (PubMed)

  9. Human Polyclonal Osteopontin Primary Antibody for ELISA, WB - ABIN185425 : Kolb, Kleeff, Guweidhi, Esposito, Giese, Adwan, Giese, Büchler, Berger, Friess: Osteopontin influences the invasiveness of pancreatic cancer cells and is increased in neoplastic and inflammatory conditions. in Cancer biology & therapy 2005 (PubMed)

More Antibodies against Osteopontin Interaction Partners

Human Secreted phosphoprotein 1 (SPP1) interaction partners

  1. Higher levels of OPN in cervical cancer patients compared to healthy subjects.OPN fragments with an intact thrombin (show F2 Antibodies)-sensitive site circulate in cervical cancer patients.

  2. Study characterized SPP1 in the human central nervous system by investigating its expression in the primary somatosensory cortex and spinal cord, in addition to primary motor cortex. Results suggest that SPP1 has a role in the specialization of motor projection neurons and suggest that its reduced expression may be implicated in the neurodegeneration seen in ALS.

  3. Study extended understanding of the effect of phosphorylation on the recombinant human-like osteopontin rOPN; showed that phosphorylation can thus selectively change the dynamic behavior of even a highly disordered protein such as osteopontin. Through such an effect on rOPN, phosphorylation can direct allosteric mechanisms, interactions with substrates, cofactors and, in this case, amorphous or crystalline biom

  4. OPN promotes chemo-resistance of hepatocellular carcinoma via autophagy pathway.

  5. OPN-a may represent a bone metastatic factor in human lung cancer, as well as a potential therapy target

  6. Data show that secreted phosphoprotein 1 (SPP1) is overexpressed in glioma initiating cells.

  7. a versatile humanized model was developed to study the action of OPN in vivo and to develop strategies that target human OPN in a variety of pathologies.

  8. Osteopontin is a key mediator released by senescent pulmonary artery smooth muscle cells and contributes to pulmonary hypertension progression.

  9. The 6007C>T polymorphism of BMP-4 (show BMP4 Antibodies), -66T>G polymorphism of OPN, and VDR (show CYP27B1 Antibodies)-FokI polymorphism are the susceptible factors of spinal TB and indicators of the clinical severity. These three genes may collaborate in the development of spinal TB.

  10. OPN is involved in HCT116 cell progression and is capable of inhibiting cell autophagy possibly by activating the p38 MAPK (show MAPK14 Antibodies) signaling pathway

Pig (Porcine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. These data suggested that methylation in the OPN promoter plays a crucial role in the regulation of OPN expression that we found in cloned pigs genome.

  2. The striking breed differences between hyperprolific Large White and Meishanin pigs of secreted phospoprotein 1 expression in endometrium suggest that SPP1 may be associated with placental efficiency.

  3. Microglia incubated in vitro with different concentrations (0.1 fM-1 nM) of recombinant osteopontin showed increased proliferation at 10 fM.

  4. results of this study reveal faster growth rate and differences in pig productivity according to genotypes of the SPP1 gene

  5. Osteopontin could play an important role in the development of neointimal hyperplasia in venous conduits after coronary artery bypass grafting.

  6. A different MSSCP pattern was shown in osteopontin which indicates that mutation is located in promotor region; the A --> G transitions was identified in two positions -617 and -608

  7. The 3' terminal end of the first intron of porcine SPP1 harbors a C/EBPbeta (show CEBPB Antibodies) binding site and this binding site is negatively affected by the mutant G allele.

  8. in pregnant pigs SPP1 is induced by conceptus estrogen in uterine luminal epithelium and is regulated in a manner coincident with placental progesterone production

  9. osteopontin promotes pathologic mineralization via calcium pyrophosphate dihydrate crystal formation in articular cartilage.

  10. Osteopontin is detected in the majority of germ cells and is involved in spermatogenesis in boar testis.

Mouse (Murine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. OPN secreted by follicular CD153 (show TNFSF8 Antibodies)(+) senescence-associated T cells in germinal centers (GCs (show UGCG Antibodies)) promotes a continuous supply of intracellular autoantigens via apoptotic cells, thus playing a key role in the progression of the autoreactive GC reaction and leading to pathogenic autoantibody production in lupus-prone mice.

  2. study demonstrated an anti-tumorigenic role of OPN in transgenic adenocarcinoma of the mouse prostate (TRAMP (show DPT Antibodies)) development and also suggests that the contribution of OPN to tumor development depends on the type of tumor as well as the source and isoform of OPN

  3. These data suggest a critical role for reduced stroma-derived osteopontin for hematopoietic stem cell aging.

  4. Osteopontin is a key mediator released by senescent pulmonary artery smooth muscle cells and contributes to pulmonary hypertension progression.

  5. Osteopontin (OPN) plays an anti-inflammatory role in acute gastrointestinal acute graft-versus-host disease (GVHD).

  6. Circulating OPN levels are upregulated in human and murine acute schistosomiasis.

  7. this study shows that neutrophil accumulation at the site of infection with a mixture of endodontic pathogens is significantly reduced in OPN-deficient mice, and is accompanied by an increase in bacterial load

  8. OPN ablation skews macrophage polarization toward a pro-regenerative phenotype.

  9. OPN induces oxidative stress via the involvement of mitochondria and NOX-4 (show NOX4 Antibodies). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK (show BIK Antibodies).

  10. Endogenous osteopontin plays a critical role in the prevention of phosphate-induced nephrocalcinosis and vascular calcification in response to high phosphate load.

Cow (Bovine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. This implies that a majority of the acidic residues within OPN must be engaged in calcium interaction under physiological conditions.

  2. Genetic variations in the SPP1 promoter affect gene expression and the level of osteopontin secretion into bovine milk.

  3. Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.

  4. osteopontin (OPN) can serve as a process-directing agent for the intrafibrillar mineralization of collagen.

  5. Results suggest a mechanism of the interaction of UO2(2+) with bone metabolism and a new role for osteopontin (OPN) as a metal transporter.

  6. Upon induction of luteolysis, SPP1 serves as a signaling molecule to recruit or activate immune cells to facilitate luteal regression and tissue degradation.

  7. OPN strongly reduces the amount of biofilm formed in a well-defined laboratory model of acidogenic dental biofilm.

  8. This study demonstrates that adhesion of isolated neonatal rat osteoclasts in vitro was augmented on bovine milk osteopontin (bmOPN) with post-translational modifications (PTMs (show PTMS Antibodies)) compared to human Escherichia-coli-derived recombinant OPN without PTMs (show PTMS Antibodies).

  9. topographical distribution of both the in vivo and in vitro phosphorylation sites of bone sialoprotein (show CRISP1 Antibodies)

  10. the bovine osteopontin gene has two functionally distinct clusters of haplotypes within the QTL region on chromosome 6

Rabbit Secreted phosphoprotein 1 (SPP1) interaction partners

  1. Infection of urinary tract by Escherichia coli caused higher than normal expression of promoter protein osteopontin and mucosal damage at renal tubular cells.

Osteopontin (SPP1) Antigen Profile

Antigen Summary

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000

Alternative names and synonyms associated with Osteopontin (SPP1)

  • secreted phosphoprotein 1 (spp1) antibody
  • secreted phosphoprotein 1 (SPP1) antibody
  • secreted phosphoprotein 1 (Spp1) antibody
  • sphingosine-1-phosphate phosphatase 1 (Sgpp1) antibody
  • sphingosine-1-phosphate phosphatase 1 (SGPP1) antibody
  • 2AR antibody
  • AI463453 antibody
  • Apl-1 antibody
  • BNSP antibody
  • Bsp antibody
  • BSPI antibody
  • Eta antibody
  • ETA-1 antibody
  • OP antibody
  • Opn antibody
  • Opnl antibody
  • OSP antibody
  • Ric antibody
  • SPP antibody
  • Spp-1 antibody
  • SPP1 antibody
  • SPPase1 antibody
  • Spph1 antibody
  • zgc:111821 antibody

Protein level used designations for SPP1

spp1 protein , osteopontin , SPP1/CALPHA1 fusion , early T-lymphocyte activation 1 , nephropontin , osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein , secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) , urinary stone protein , uropontin , SPP-1 , bone sialoprotein 1 , 44 kDa bone phosphoprotein , calcium oxalate crystal growth inhibitor protein , early T-lymphocyte activation 1 protein , minopontin , osteopontin-like protein , Sialoprotein (osteopontin) , bone sialoprotein I , osteopontin-K , OC-1 , secreted phosphoprotein-1 , SPPase1 , sphingosine-1-phosphatase 1 , hSPP1 , hSPPase1 , spp1

GENE ID SPECIES
432385 Danio rerio
6696 Homo sapiens
478471 Canis lupus familiaris
397087 Sus scrofa
20750 Mus musculus
25353 Rattus norvegicus
281499 Bos taurus
100008982 Oryctolagus cuniculus
395210 Gallus gallus
443058 Ovis aries
100860805 Capra hircus
81535 Mus musculus
81537 Homo sapiens
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