Browse our Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins (SEMA3A)

Full name:
Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins (SEMA3A)
On www.antibodies-online.com are 18 Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) Proteins from 8 different suppliers available. Additionally we are shipping Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Antibodies (68) and Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Kits (44) and many more products for this protein. A total of 133 Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A products are currently listed.
Synonyms:
COLL-1, COLL1, Dsema3a, fj37c11, HH16, Hsema-I, Hsema-III, SEMA1, Sema3A, Semad, SEMAIII, SEMAL, SemD, si:ch211-120m13.2, wu:fj37c11
list all proteins Gene Name GeneID UniProt
SEMA3A 10371 Q14563
SEMA3A 20346 O08665
SEMA3A 29751 Q63548

Show all synonyms

Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins (SEMA3A) by Origin

Select your origin of interest

Top referenced Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins

  1. Mouse (Murine) SEMA3A Protein expressed in Human Cells - ABIN2008081 : Chadborn, Ahmed, Holt, Prinjha, Dunn, Jones, Eickholt: PTEN couples Sema3A signalling to growth cone collapse. in Journal of cell science 2006 (PubMed)
    Show all 3 references for 2008081

  2. Human SEMA3A Protein expressed in Human Cells - ABIN2003354 : Schmidt, Strittmatter: The CRMP family of proteins and their role in Sema3A signaling. in Advances in experimental medicine and biology 2007 (PubMed)
    Show all 2 references for 2003354

More Proteins for Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) interaction partners

  1. EV-delivered Sema3A orchestrates loss of barrier integrity in glioblastoma

  2. IL6 (show IL6 Proteins) underexpression is associated with Breast Cancer.

  3. We also demonstrate that the effects of RET (show RET Proteins) and NRG1 (show NRG1 Proteins) are universal across European and Asian ancestries. In contrast, we detected a European-specific association of a low-frequency variant, rs80227144, in SEMA3. Conditional analyses on the lead SNPs revealed a secondary association signal, corresponding to an Asian-specific, low-frequency missense variant encoding RET (show RET Proteins) p.Asp489Asn

  4. Semaphorin3A serum concentrations were similar in ankylosing spondylitis patients and controls and were not altered on treatment in anti-TNF (show TNF Proteins) agents.

  5. The self-renewal ability abolished by Sema3a knockdown could not be recovered by exogenous addition of recombinant SEMA3A. In addition, the activity of mammalian target of rapamycin (show FRAP1 Proteins) complex 1 (mTORC1) and the expression of its substrate p70S6K1 (show RPS6KB1 Proteins) were also decreased. These results demonstrate that Sema3a is a potential therapeutic target in eradication of CSCs.

  6. Study shows a significant reduction of the serum Sema3A level and its mRNA expression in peripheral blood mononuclear cells in patients with relapsing-remitting multiple sclerosis compared with normal individuals.

  7. Sema3A expression on T and B regulatory lymphocytes is low in familial Mediterranean fever (show MEFV Proteins) patients during attack and in smoldering disease compared to the expression in remission and healthy controls.

  8. Tumor cells decrease Sema3a mRNA expression in osteoblasts in an mTORC1-dependent manner.

  9. Semaphorin-3a, neuropilin-1 (show NRP1 Proteins) and plexin-A1 (show PLXNA1 Proteins) are axonal guidance molecules that have been recently implicated in regulating bone metabolism.

  10. Sema3A and sema7A (show SEMA7A Proteins) expression correlated with the inflammatory activity of the multiple sclerosis (MS) lesions, suggesting their involvement in the immunological process that takes place in MS.

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) interaction partners

  1. We show that PTP-3, a LAR (show PTPRF Proteins) homolog in Caenorhabditis elegans, participates in Sema2A-regulated axon guidance. PTPdelta, a member of vertebrate LAR (show PTPRF Proteins) class PTPs (show PTS Proteins), is involved in Sema3A-regulated cortical dendritic growth. In Sema3A signaling, PTPdelta activates Fyn (show FYN Proteins) and Src (show SRC Proteins) kinases by dephosphorylating their C-terminal Tyr (show TYR Proteins) residues.

  2. Investigated the effects of BotoxA-induced paralysis on the sprouting capacity of neuromuscular junctions (NMJs) in the K108N-SEMA3A mutant, and observed no change in the differential neuronal plasticity found at NMJs on fast-fatigable or slow muscle fibers due to the presence of the SEMA3A mutant protein.

  3. The aim was to elucidate whether ectopic muscles are a result of misguidance of myoblast precursors due to the loss of Sema3A-Npn-1 (show NRP1 Proteins) signaling.

  4. These findings suggest that by interacting with PlexA4 (show PLXNA4 Proteins), TrkA (show NTRK1 Proteins) plays a crucial role in redirecting local Sema3A signaling to retrograde axonal transport, thereby regulating dendritic GluA2 (show GRIA2 Proteins) localization and patterning.

  5. Findings indicate that Rho and ROCK knockout may improve the behavior of mice and prevent MPTP (show PTPN2 Proteins)-induced dopaminergic neurons damage by regulating Sema3A, PlexinA and NRP-1 (show NRP1 Proteins) in a mouse model of Parkinson's disease.

  6. Sema3A signaling exerts its oncogenic effect by promoting an mTORC1-mediated metabolic shift from oxidative phosphorylation to aerobic glycolysis.

  7. Semaphorin 3A (Sema3A) is a protein secreted during the development of the nervous system that acts as a cue for axon induction .

  8. this paper shows that Nav1.7 (show SCN9A Proteins), by coupling with CRMP1 (show CRMP1 Proteins), mediates the axonal retrograde signaling of Sema3A in axonal guidance

  9. miR (show MLXIP Proteins)-30c and sema3A regulate adult neurogenesis by controlling proliferation and differentiation of stem cells in the subventricular zone.

  10. These findings indicate that endothelial cell-derived Sema3A exerts repelling functions on VEGF-A (show VEGFA Proteins)-induced tip cell filopodia and that a lack of this signaling cannot be rescued by paracrine sources of Sema3A.

Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) Protein Profile

Protein Summary

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Alternative names and synonyms associated with Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A)

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (SEMA3E)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (sema3e)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (LOC100230255)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (SEMA3A)
  • Sema-3a (Sema-3a)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (Sema3a)
  • semaphorin-3A-like (LOC100357227)
  • COLL-1 protein
  • COLL1 protein
  • Dsema3a protein
  • fj37c11 protein
  • HH16 protein
  • Hsema-I protein
  • Hsema-III protein
  • SEMA1 protein
  • Sema3A protein
  • Semad protein
  • SEMAIII protein
  • SEMAL protein
  • SemD protein
  • si:ch211-120m13.2 protein
  • wu:fj37c11 protein

Protein level used designations for SEMA3A

semaphorin 3E , semaphorin-3E , sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A , semaphorin 3A , semaphorin-3A-like , collapsin 1 , semaphorin D , semaphorin III , semaphorin L , semaphorin-3A , collapsin-1 , sema D , sema III , semaphorin-D , Semaphorin 3a , sema domain, immunoglobulin domain (Ig), short basic domain, sec , collapsin

GENE ID SPECIES
472429 Pan troglodytes
565658 Danio rerio
100230255 Taeniopygia guttata
483386 Canis lupus familiaris
745878 Pan troglodytes
5657999 Drosophila melanogaster
100458068 Pongo abelii
100587973 Nomascus leucogenys
10371 Homo sapiens
20346 Mus musculus
29751 Rattus norvegicus
395825 Gallus gallus
100731288 Cavia porcellus
100357227 Oryctolagus cuniculus
Selected quality suppliers for Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins (SEMA3A)
Did you look for something else?