Browse our ULK1 Proteins (ULK1)

Full name:
Unc-51 Like Kinase 1 (C. Elegans) Proteins (ULK1)
On www.antibodies-online.com are 15 Unc-51 Like Kinase 1 (C. Elegans) (ULK1) Proteins from 7 different suppliers available. Additionally we are shipping ULK1 Antibodies (260) and ULK1 Kits (4) and many more products for this protein. A total of 289 ULK1 products are currently listed.
Synonyms:
ATG1, ATG1A, AU041434, hATG1, mKIAA0722, si:dkey-11o18.7, ulk1, UNC51, Unc51.1
list all proteins Gene Name GeneID UniProt
ULK1 8408 O75385
Rat ULK1 ULK1 360827  
Mouse ULK1 ULK1 22241 O70405

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ULK1 Proteins (ULK1) by Origin

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Human Unc-51 Like Kinase 1 (C. Elegans) (ULK1) interaction partners

  1. ULK1/2 function as a bifurcate-signaling node that sustains glucose metabolic fluxes besides initiation of autophagy in response to nutritional deprivation.

  2. these results demonstrate the effective anti-autophagic of NRAGE (show MAGED1 Proteins) in non-small-cell lung cancer cells through AMPK (show PRKAA1 Proteins)/Ulk1/Atg13 (show ATG13 Proteins) autophagy signaling pathways. Therefore, NRAGE (show MAGED1 Proteins) could be used as a potential therapeutic target for lung cancer.

  3. results from western blotting assays and immunoprecipitation assays displayed that sirtuin 6 (show SIRT6 Proteins) specifically interacted with ULK1 and positively regulated its activity by inhibiting its upstream factor mammalian target of rapamycin (show FRAP1 Proteins) activity.

  4. As a Rab1a (show RAB1A Proteins) effector, C9orf72 (show C9ORF72 Proteins) controls initiation of autophagy by regulating the Rab1a (show RAB1A Proteins)-dependent trafficking of the ULK1 autophagy initiation complex to the phagophore.

  5. Ulk1 promoted the degradation of Hsp90 (show HSP90 Proteins)-Cdc37 (show CDC37 Proteins) client kinases, resulting in increased cellular sensitivity to Hsp90 (show HSP90 Proteins) inhibitors. Thus, our study provides evidence for an anti-proliferative role of Ulk1 in response to Hsp90 (show HSP90 Proteins) inhibition in cancer cells

  6. Here, the authors demonstrate that S100A10 (show S100A10 Proteins) is required for ULK1 localization to autophagosome formation sites. Silencing of S100A10 (show S100A10 Proteins) reduces IFN-gamma-induced (show SAMHD1 Proteins) autophagosome formation.

  7. A strong association of rs12297124, a noncoding ULK1 SNP, with LTBI and a role for ULK1 regulation of TNF (show TNF Proteins) secretion.

  8. High expression of ULK1 concomitant with high expression of LRPPRC (show LRPPRC Proteins) may serve as useful markers for shorter biochemical progression (BCP (show OPN1SW Proteins))-free survival and overall survival in patients with metastatic prostate cancer (PCa (show FLVCR1 Proteins)) after androgen deprivation therapy (ADT).

  9. These results thus place NEDD4L (show NEDD4L Proteins) and ULK1 in a key position to control oscillatory activation of autophagy during prolonged stress to keep the levels of this process under a safe and physiological threshold.

  10. These results demonstrate a novel mechanism by which STAT1 (show STAT1 Proteins) negatively regulates ULK1 expression and autophagy.

Mouse (Murine) Unc-51 Like Kinase 1 (C. Elegans) (ULK1) interaction partners

  1. ULK1 is a novel substrate of Caspase-3 (show CASP3 Proteins) and upregulation of ULK1 drives autophagy initiation in leukemia cells.

  2. Findings indicate that the PPM1D (show PPM1D Proteins)-Ulk1 axis plays a pivotal role in genotoxic stress-induced autophagy.

  3. Regulation of endoplasmic reticulum-to-Golgi trafficking by ULK1/2 is essential for cellular homeostasis.

  4. Ulk1-mediated autophagy plays an essential role in mitochondrial remodeling and functional regeneration of skeletal muscle.

  5. ULK1/2 function as a bifurcate-signaling node that sustains glucose metabolic fluxes besides initiation of autophagy in response to nutritional deprivation.

  6. These results demonstrate a novel mechanism by which STAT1 (show STAT1 Proteins) negatively regulates ULK1 expression and autophagy.

  7. These results define a key molecular event for the starvation-induced activation of the ATG14-containing PtdIns3K complex by ULK1.

  8. By enhancing PARP1 (show PARP1 Proteins) activity, ULK1 contributes to ATP depletion and death of H2O2-treated cells.

  9. MUL1 (show MUL1 Proteins) ubiquitinates ULK1 and regulates selenite-induced mitophagy

  10. autophagy can be executed by mechanisms that are dependent or independent of the ULK1/2-ATG13 (show ATG13 Proteins) interaction.

ULK1 Protein Profile

Protein Summary

predicted to have similarity to C. elegans serine/threonine kinase UNC-51

Alternative names and synonyms associated with ULK1

  • unc-51-like kinase 1 (C. elegans) (ULK1)
  • unc-51-like kinase 1b (C. elegans) (ulk1b)
  • unc-51 like autophagy activating kinase 1 (ULK1)
  • unc-51 like autophagy activating kinase 1 (Ulk1)
  • unc-51 like kinase 1 (Ulk1)
  • ATG1 protein
  • ATG1A protein
  • AU041434 protein
  • hATG1 protein
  • mKIAA0722 protein
  • si:dkey-11o18.7 protein
  • ulk1 protein
  • UNC51 protein
  • Unc51.1 protein

Protein level used designations for ULK1

unc-51-like kinase 1 (C. elegans) , serine/threonine-protein kinase ULK1 , unc-51-like kinase 1 , ATG1 autophagy related 1 homolog , autophagy-related protein 1 homolog , serine/threonine-protein kinase Unc51.1

GENE ID SPECIES
416800 Gallus gallus
477437 Canis lupus familiaris
526310 Bos taurus
558848 Danio rerio
744289 Pan troglodytes
100062311 Equus caballus
8408 Homo sapiens
360827 Rattus norvegicus
22241 Mus musculus
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