anti-Mouse (Murine) Integrin beta 3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Integrin beta 3 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 3 (ITGB3) Antibodies
  • CD61
  • GP3A
  • INGRB3
  • BDPLT16
  • BDPLT2
  • GPIIIa
  • GT
  • INTB3
  • integrin
  • GPIIIA
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • integrin beta 3
  • integrin, beta 3
  • ITGB3
  • Itgb3
Epitope
AA 27-77
49
43
33
24
19
19
17
14
9
8
6
4
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
602
248
203
28
27
25
24
19
16
13
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
Host
Rabbit
378
237
52
29
28
4
1
Clonality
Polyclonal
Conjugate
This Integrin beta 3 antibody is un-conjugated
78
54
27
22
18
14
13
13
13
10
9
8
8
8
7
7
7
7
6
6
6
5
2
2
2
2
2
2
2
Application
ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
440
282
167
136
111
91
81
75
65
26
14
13
12
8
6
5
5
4
2
2
2
1
1
1
Options
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Catalog No. ABIN739029
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.972137 ABIN449350 IHC (p) IHC WB Rabbit Log in to see Polyclonal
1 ABIN3043262 IHC (p) WB Rabbit IgG AA 753-786, C-Term Log in to see Polyclonal
1 ABIN197246 IHC (p) WB Rabbit AA 771-775 Log in to see Polyclonal 3
1 ABIN196720 IHC (p) WB Rabbit pTyr773 Log in to see Polyclonal 3
1 ABIN4327087 Func IA IHC IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see BV4 6
1 ABIN2689353 IHC (fro) FACS IHC (p) Armenian Hamster IgG1, kappa Log in to see 2C9-G2 5
1 ABIN265480 EIA IHC (p) Rabbit Log in to see Polyclonal
1 ABIN2689352 BR IHC (fro) FACS IHC (p) Armenian Hamster IgG1, kappa Log in to see 2C9-G2 7
1 ABIN739038 ELISA IHC (p) WB HRP Rabbit IgG AA 27-77 Log in to see Polyclonal
1 ABIN739031 ELISA IHC (p) WB Biotin Rabbit IgG AA 27-77 Log in to see Polyclonal
1 ABIN2888445 IHC (p) ELISA WB Rabbit IgG pTyr773 Log in to see Polyclonal
1 ABIN318050 IHC (p) WB Rabbit pTyr773 Log in to see Polyclonal
1 ABIN408417 IHC (p) IHC WB Rabbit pTyr773 Log in to see Polyclonal
1 ABIN2624358 IHC (p) WB Rabbit IgG AA 752-770 Log in to see Polyclonal
1 ABIN596000 IHC (p) WB Rabbit IgG pTyr773 Log in to see Polyclonal
1 ABIN802287 IHC (p) WB HRP Rabbit IgG pTyr785 Log in to see Polyclonal
1 ABIN2891460 IHC (p) WB Rabbit pThr767 Log in to see Polyclonal
1 ABIN802280 IHC (p) WB Biotin Rabbit IgG pTyr785 Log in to see Polyclonal
1 ABIN802278 IF (p) IHC (p) WB Rabbit IgG pTyr785 Log in to see Polyclonal
1 ABIN802263 IF (p) IHC (p) WB Rabbit IgG pTyr773 Log in to see Polyclonal

General

Antigen Integrin beta 3 (ITGB3) Antibodies
Epitope AA 27-77
(49), (43), (33), (24), (19), (19), (17), (14), (9), (8), (6), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(602), (248), (203), (28), (27), (25), (24), (19), (16), (13), (6), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(378), (237), (52), (29), (28), (4), (1)
Clonality
Polyclonal
Conjugate This Integrin beta 3 antibody is un-conjugated
(78), (54), (27), (22), (18), (14), (13), (13), (13), (10), (9), (8), (8), (8), (7), (7), (7), (7), (6), (6), (6), (5), (2), (2), (2), (2), (2), (2), (2)
Application ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(440), (282), (167), (136), (111), (91), (81), (75), (65), (26), (14), (13), (12), (8), (6), (5), (5), (4), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Integrin beta 3 Antibody

Target Details Integrin beta 3 Application Details Handling References for anti-Integrin beta 3 antibody (ABIN739029) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human Integrin beta 3
Isotype IgG

Target Details Integrin beta 3

Product Details anti-Integrin beta 3 Antibody Application Details Handling References for anti-Integrin beta 3 antibody (ABIN739029) Images back to top
Antigen
Alternative Name Integrin beta 3 (ITGB3 Antibody Abstract)
Background

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Subcellular location: Extracellular

Synonyms: GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, Integrin beta-3, Platelet membrane glycoprotein IIIa, ITGB3

Molecular Weight 87kDa
Gene ID 3690
UniProt P05106
Research Area Cardiovascular, Atherosclerosis, Angiogenesis, Cell/Tissue Markers, Extracellular Matrix, Signaling
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex

Application Details

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Handling References for anti-Integrin beta 3 antibody (ABIN739029) Images back to top
Application Notes WB 1:100-1000
ELISA 1:500-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details References for anti-Integrin beta 3 antibody (ABIN739029) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-Integrin beta 3 antibody (ABIN739029)

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling Images back to top
Product cited in:

Zhou, Qu, Sun, Wu, Liu, Yang, Zhang: "Sophoricoside fails the embryo implantation by compromising the uterine endometrial receptivity at implantation "window" of pregnant mice." in: Chemico-biological interactions, Vol. 219C, pp. 57-63, 2014

Wang, Jiang, Peng, Guo, Shang, Chen, Wu, Chen: "Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates." in: Biomaterials, Vol. 34, Issue 15, pp. 3737-46, 2013

Li, Liu, Kan, Li, Liu, Lu: "Elevated expression of integrin αv and β5 subunit in laryngeal squamous-cell carcinoma associated with lymphatic metastasis and angiogenesis." in: Pathology, research and practice, Vol. 209, Issue 2, pp. 105-9, 2013

Images

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling References for anti-Integrin beta 3 antibody (ABIN739029) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Integrin beta 3 (ITGB3) (AA 27-77) antibody (ABIN739029) Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-Integri...
Western Blotting (WB) image for anti-Integrin beta 3 (ITGB3) (AA 27-77) antibody (ABIN739029) Mouse placenta lysates probed withAnti-Integrin beta 3 Polyclonal Antibody, Unconjuga...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin beta 3 (ITGB3) (AA 27-77) antibody (ABIN739029) Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-Integri...
Flow Cytometry (FACS) image for anti-Integrin beta 3 (ITGB3) (AA 27-77) antibody (ABIN739029) Human HL-60 cells probed with Integrin beta 3 Polyclonal Antibody, Unconjugated (gre...