anti-Rat (Rattus) Integrin beta 3 antibody for Mass Cytometry

Recommended Integrin beta 3 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 3 (ITGB3) Antibodies
  • CD61
  • GP3A
  • INGRB3
  • BDPLT16
  • BDPLT2
  • GPIIIa
  • GT
  • INTB3
  • integrin
  • GPIIIA
  • integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
  • integrin beta 3
  • integrin, beta 3
  • ITGB3
  • Itgb3
Reactivity
Mouse (Murine), Rat (Rattus)
585
239
202
28
27
25
24
19
16
13
6
5
4
4
4
3
2
2
2
2
2
2
1
1
1
1
Host
Hamster
369
231
51
29
19
2
1
Clonality
Monoclonal
Conjugate
This Integrin beta 3 antibody is conjugated to PE
78
52
26
20
16
13
12
11
11
10
9
7
7
7
7
6
6
6
6
6
6
5
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Mass Cytometry (CyTOF)
418
274
163
136
112
91
80
75
64
27
13
13
8
6
6
5
5
4
2
2
2
1
1
1
1
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Catalog No. ABIN2663541
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2663542 FACS CyTOF PE Hamster IgG Log in to see 2C9-G2 (HMbeta3-1) 9

Top referenced anti-Integrin beta 3 antibody for Mass Cytometry

Similar anti-Integrin beta 3 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Blocking Reagent (BR) 4 Antibodies 2 Antibodies
ELISA 22 Antibodies
Flow Cytometry (FACS) 119 Antibodies
Functional Studies (Func) 6 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 21 Antibodies
Immunofluorescence (IF) 22 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 14 Antibodies
Immunohistochemistry (IHC) 59 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 48 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 21 Antibodies
Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)) 2 Antibodies
Immunoprecipitation (IP) 41 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Western Blotting (WB) 68 Antibodies

General

Antigen Integrin beta 3 (ITGB3) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(585), (239), (202), (28), (27), (25), (24), (19), (16), (13), (6), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Host Hamster
(369), (231), (51), (29), (19), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 3 antibody is conjugated to PE
(78), (52), (26), (20), (16), (13), (12), (11), (11), (10), (9), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (5), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Mass Cytometry (CyTOF)
(418), (274), (163), (136), (112), (91), (80), (75), (64), (27), (13), (13), (8), (6), (6), (5), (5), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-Integrin beta 3 Antibody

Target Details Integrin beta 3 Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541) Images
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 2C9-G2 (HMbeta3-1)
Isotype IgG

Target Details Integrin beta 3

Product Details anti-Integrin beta 3 Antibody Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541) Images back to top
Antigen
Alternative Name CD61 (ITGB3 Antibody Abstract)
Background CD61 is a 110 kD integrin β chain also known as β3 integrin or gpIIIa. It associates with the integrin αv chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin αIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of αv/β3 integrin or vitronectin receptor to CD31 (PECAM-1).
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex

Application Details

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541)

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling Images back to top
Background publications

Yamaji, Na, Feuermann, Pechhold, Chen, Robinson, Hennighausen: "Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A." in: Genes & development, Vol. 23, Issue 20, pp. 2382-7, 2009

Carlson, Hu, Braren, Kim, Wang: "Cell-autonomous requirement for beta1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice." in: Development (Cambridge, England), Vol. 135, Issue 12, pp. 2193-202, 2008

Ashkar, Weber, Panoutsakopoulou, Sanchirico, Jansson, Zawaideh, Rittling, Denhardt, Glimcher, Cantor: "Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity." in: Science (New York, N.Y.), Vol. 287, Issue 5454, pp. 860-4, 2000

Piali, Hammel, Uherek, Bachmann, Gisler, Dunon, Imhof: "CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endothelium." in: The Journal of cell biology, Vol. 130, Issue 2, pp. 451-60, 1995

Schultz, Armant: "Beta 1- and beta 3-class integrins mediate fibronectin binding activity at the surface of developing mouse peri-implantation blastocysts. Regulation by ligand-induced mobilization of stored receptor." in: The Journal of biological chemistry, Vol. 270, Issue 19, pp. 11522-31, 1995

Felding-Habermann, Cheresh: "Vitronectin and its receptors." in: Current opinion in cell biology, Vol. 5, Issue 5, pp. 864-8, 1993

Phillips, Charo, Scarborough: "GPIIb-IIIa: the responsive integrin." in: Cell, Vol. 65, Issue 3, pp. 359-62, 1991

Kieffer, Phillips: "Platelet membrane glycoproteins: functions in cellular interactions." in: Annual review of cell biology, Vol. 6, pp. 329-57, 1991

Moulder, Roberts, Shevach, Coligan: "The mouse vitronectin receptor is a T cell activation antigen." in: The Journal of experimental medicine, Vol. 173, Issue 2, pp. 343-7, 1991

Images

Product Details anti-Integrin beta 3 Antibody Target Details Integrin beta 3 Application Details Handling ProductDetails: References for anti-Integrin beta 3 antibody (ABIN2663541) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin beta 3 antibody (ITGB3)  (PE) (ABIN2663541) anti-Integrin beta 3 (ITGB3) antibody (PE)