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Browse our anti-Metabotropic Glutamate Receptor 5 (GRM5) Antibodies

Full name:
anti-Glutamate Receptor, Metabotropic 5 Antibodies (GRM5)
On www.antibodies-online.com are 152 Glutamate Receptor, Metabotropic 5 (GRM5) Antibodies from 23 different suppliers available. Additionally we are shipping Metabotropic Glutamate Receptor 5 Kits (18) and Metabotropic Glutamate Receptor 5 Proteins (7) and many more products for this protein. A total of 184 Metabotropic Glutamate Receptor 5 products are currently listed.
Synonyms:
6430542K11Rik, AI850523, Glu5R, Gprc1e, mGlu5, mGlur5, mGluR5b

Most Popular Reactivities for anti-Metabotropic Glutamate Receptor 5 (GRM5) Antibodies

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anti-Human Metabotropic Glutamate Receptor 5 Antibodies:

anti-Rat (Rattus) Metabotropic Glutamate Receptor 5 Antibodies:

anti-Mouse (Murine) Metabotropic Glutamate Receptor 5 Antibodies:

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Top referenced anti-Metabotropic Glutamate Receptor 5 Antibodies

  1. Human Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for EIA, WB - ABIN358930 : Pacheco, Ciruela, Casadó, Mallol, Gallart, Lluis, Franco: Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358930

  2. Human Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for WB - ABIN390320 : Corti, Clarkson, Crepaldi, Sala, Xuereb, Ferraguti: Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN390320

  3. Dog (Canine) Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for IHC (fro), IF - ABIN783986 : Francesconi, Kumari, Zukin: Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 2 references for ABIN783986

  4. Mouse (Murine) Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for IHC (fro), IHC - ABIN152473 : Spanagel, Pendyala, Abarca, Zghoul, Sanchis-Segura, Magnone, Lascorz, Depner, Holzberg, Soyka, Schreiber, Matsuda, Lathrop, Schumann, Albrecht: The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. in Nature medicine 2005 (PubMed)
    Show all 2 references for ABIN152473

  5. Mouse (Murine) Polyclonal Metabotropic Glutamate Receptor 5 Primary Antibody for ICC, IHC - ABIN1742080 : Ferraguti, Shigemoto: Metabotropic glutamate receptors. in Cell and tissue research 2006 (PubMed)

  6. Human Monoclonal Metabotropic Glutamate Receptor 5 Primary Antibody for ICC, IF - ABIN1027721 : Keinänen, Wisden, Sommer, Werner, Herb, Verdoorn, Sakmann, Seeburg: A family of AMPA-selective glutamate receptors. in Science (New York, N.Y.) 1990 (PubMed)

More Antibodies against Metabotropic Glutamate Receptor 5 Interaction Partners

Human Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. Overall, these data posit mGluR5 in key paralimbic areas as a strong determinant of the temperament trait novelty seeking. These data add to our understanding of how brain neurochemistry accounts for the variation in human behavior and strongly support further research on mGluR5 as a potential therapeutic target in neuropsychiatric disorders associated with abnormal novelty-seeking behaviors.

  2. Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P (show TAC1 Antibodies) immunoreactivity in Huntington's disease

  3. The metabotropic glutamate (show GRIN1 Antibodies) receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders.

  4. The interaction between GRM5 and cellular prion protein (show PRNP Antibodies) has a central role in transgenic mouse model of Alzheimer's disease pathogenesis.

  5. Data suggest that metabotropic glutamate receptors recycling is completely dependent on the activity of PP2A whereas, PP2B has partial effect on this process.

  6. findings provide evidence for decreased expression of metabotropic glutamate receptor 5 and its signaling components representing a key pathophysiological hallmark in autism spectrum disorder.

  7. Study provided evidence that protein expression of mGluR5 is significantly higher (total: 42%; monomer: 25%; dimer: 52%) in the hippocampal CA1 (show CA1 Antibodies) region of schizophrenia subjects relative to healthy controls

  8. Results provide compelling evidence that mGluR5 regulation is altered in schizophrenia, likely contributing to the altered glutamatergic signaling that is associated with the disorder

  9. This review supports altered mGluR5 functioning as a convergent point in ASD (show ARSD Antibodies) pathogenesis and indicates more research is warranted into mGluR5 as a potential therapeutic target.

  10. both an increased and reduced mGlu5 functioning seem to be associated with Intellectual Disability and autism spectrum disorders.

Mouse (Murine) Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. The present results showed that ER knockout alpha and beta male mice had lower striatal mGlu5 receptor binding and protein measured by Western blot.

  2. These results suggest that PrP(C (show PRNP Antibodies))-mGluR5 form a functional response unit by which multiple ligands can trigger signaling. We propose that trafficking of PrP(C (show PRNP Antibodies))-mGluR5 may modulate signaling intensity by different PrP(C (show PRNP Antibodies)) ligands.

  3. GluD1 (show GLUD1 Antibodies) interacts with mGlu5, and loss of GluD1 (show GLUD1 Antibodies) impairs normal mGlu5 signaling potentially by dysregulating coupling to its effector.

  4. This study further distinguishes two separate Abetao-dependent signaling cascades, one dependent on extracellular Ca(2 (show CA2 Antibodies)+) and Fyn (show FYN Antibodies) kinase activation and the other dependent on the release of Ca(2 (show CA2 Antibodies)+) from intracellular stores. Thus, Abetao triggers multiple distinct PrP(C (show PRNP Antibodies))-mGluR5-dependent events implicated in neurodegeneration and dementia.

  5. mGluR5 may mediate amyloid beta synaptotoxicity and it is a novel therapeutic targets for AD and other cognitive syndromes.

  6. Dysregulation of fragile X mental retardation protein (show NUFIP2 Antibodies)-metabotropic glutamate receptor 5 signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  7. Our findings suggest a fundamental role for mGluR5 in the development of Pv(+) neurons and show that alterations in this system can produce broad-spectrum alterations in brain network activity

  8. This work provides strong evidence that Homer (show HOMER1 Antibodies)-mGlu5 binding contributes to symptoms associated with neurodevelopmental disorders

  9. This study identify highly specialized roles of lateral septal mGluR5 and Oxtr (show OXTR Antibodies) in the the regulation of discrete social behaviors, and suggest that deficits in social interactions.

  10. Results offer the first evidence that changes in the striatal expression of mGlu4 (show GRM4 Antibodies) and mGlu5 receptors occur in acute models of parkinsonisms

Metabotropic Glutamate Receptor 5 (GRM5) Antigen Profile

Antigen Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Metabotropic Glutamate Receptor 5 (GRM5)

  • glutamate receptor, metabotropic 5 (GRM5) antibody
  • glutamate receptor, metabotropic 5 (Grm5) antibody
  • 6430542K11Rik antibody
  • AI850523 antibody
  • Glu5R antibody
  • Gprc1e antibody
  • mGlu5 antibody
  • mGlur5 antibody
  • mGluR5b antibody

Protein level used designations for GRM5

metabotropic glutamate receptor 5 , metabotropic glutamate receptor 5 variant F , metabotropic glutamate receptor 5 variant G , metabotropic glutamate receptor 5 variant H , metabotropic glutamate receptor (mGluR5) , metabotropic glutamate receptor 5b , G protein coupled receptor, family C, group 1, member E , G protein-coupled receptor GRM5 , G protein-coupled receptor, family C, group 1, member E , metabotropic glutamate receptor subtype 5b , metabotropic glutamate receptor type 5

GENE ID SPECIES
373933 Gallus gallus
2915 Homo sapiens
24418 Rattus norvegicus
108071 Mus musculus
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