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High nuclear CD24 expression in stromal cells is associated with bladder cancer.
While no obvious role was found for CD24 in the normal development and maintenance of the dopaminergic nigrostriatal system in mice, it may have a role in mediating the neuroprotective aspects of GDNF in this system.
Expression of CDH1 (show CDH1 ELISA Kits) and CD24 was transcriptionally upregulated by direct binding of HOXA5 (show HOXA5 ELISA Kits) to their promoter sequences as demonstrated by luciferase and ChIP analyses
CD24 is a highly sensitive and specific marker of ovarian carcinoma in the differential diagnosis from malignant mesothelioma and reactive mesothelium in effusions.
These data suggest a significant association of CD24 genetic variants with prostate cancer onset and progression, which provides new insight into molecular genetics of prostate cancer.
CD24 cell surface expression may serve as a valuable biomarker in order to identify mammary tumors that will positively respond to targeted IGF1R (show IGF1R ELISA Kits) therapies.
co-expression of CD90 (show THY1 ELISA Kits) and CD24 may have an important role in the development and progression of pancreatic intraepithelial neoplasia.
CD24 expression level directly affects cisplatin sensitivity and affects the expression of critical apoptotic, stem and drug resistance genes.
CD44 (show CD44 ELISA Kits)+/24- and ALDH1 (show ALDH1A1 ELISA Kits)-positive rates in primary tumors differed according to intrinsic subtype. ER-positive patients with CD44 (show CD44 ELISA Kits)+/24- tumors had significantly longer disease-free-survival than all other ER-positive patients
CD44 (show CD44 ELISA Kits)+/CD24- cells were present in all tumor tissues. The percentage of CD44 (show CD44 ELISA Kits)+/CD24- cells was higher in early-stage disease, but without statistical significance.
mice negative or positive for CD24 did not differ in terms of tumor initiation and burden in 3 mammary and prostate tumor models tested, except for Apc1572T/+ mice, in which lack of CD24 reduced the mammary tumor burden slightly but significantly.
Loss of CD24 in Mice Leads to Metabolic Dysfunctions and a Reduction in White Adipocyte Tissue.
CD24 controls breast cancer radiation response. Loss of CD24 expression leads to radiation resistance.
Delayed wound-healing in the absence of HSA/CD24 suggests that CD24 plays an important role in this process
Findings indicate that CD24(+) antigen cells play a role in tumor migration and metastasis and support Janus kinase 2 (show JAK2 ELISA Kits) protein (JAK2 (show JAK2 ELISA Kits)) as a therapeutic target in ovarian cancer.
CD24 is a conserved marker for tracking divergent states in both reprogramming and standard pluripotent culture.
CD24 in non-immune cells might be crucialfor the guidance and recruitment of leukocytes.
CD24 expression negatively regulates the NF-kappaB (show NFKB1 ELISA Kits) pathway following experimental traumatic brain injury.
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and in many B cells. The encoded protein is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface.
CD24 antigen (small cell lung carcinoma cluster 4 antigen)
, signal transducer CD24
, CD24 antigen
, heat-stable antigen
, nectadrin heat stable antigen
, M1/69-J11D heat stable antigen
, X62 heat stable antigen
, cluster of differentiation 24
, heat stable antigen
, lymphocyte antigen 52