Browse our CD45 (PTPRC) ELISA Kits

Full name:
Protein tyrosine Phosphatase, Receptor Type, C ELISA Kits (PTPRC)
On www.antibodies-online.com are 17 Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) ELISA Kits from 6 different suppliers available. Additionally we are shipping CD45 Antibodies (2355) and CD45 Proteins (33) and many more products for this protein. A total of 2414 CD45 products are currently listed.
Synonyms:
B220, cd45, CD45R, GP180, L-CA, Lca, loc, Ly-5, LY5, Lyt-4, PTPRC, RT7, si:dkeyp-47c5.1, T200
list all ELISA KIts Gene Name GeneID UniProt
PTPRC 5788 P08575
PTPRC 19264  
PTPRC 24699 P04157

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More ELISA Kits for CD45 Interaction Partners

Human Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) interaction partners

  1. Our findings suggest that CD45 is a key regulator of BCR (show BCR ELISA Kits)-signaling thresholds mediated by T-cell help

  2. we demonstrate for the first time the physiological existence of ct-CD45 in human plasma and show that it may be an extrinsic factor contributing to the maintenance of human T-cell quiescence.

  3. Our findings suggest that if w/h ratio on SSC (show CYP11A1 ELISA Kits) versus CD45 plot is less than 1.6, AML (show RUNX1 ELISA Kits) may be considered, and if it is more than 1.6, ALL may be diagnosed. Using morphometric analysis of the blast cluster on SSC (show CYP11A1 ELISA Kits) versus CD45, it was possible to distinguish between ALL and AML (show RUNX1 ELISA Kits), and their subtypes.

  4. Use of the common leukocyte marker CD45 increases the sensitivity of the diagnosis of lymphocytic myocarditis.

  5. Review/Meta-analysis: Rheumatoid arthritis patients with PTPRC rs10919563 A allele show a poor response to anti-TNF (show TNF ELISA Kits) therapy.

  6. Data suggest that CD41 and CD45 expression marked the onset of haemangioblastoma (HB) neovascularisation and the stepwise development of the angioformative period, and also the underlying therapeutic targets of anti-vascular treatment.

  7. PTPRC has become the most replicated genetic biomarker of response to TNF (show TNF ELISA Kits) inhibitors

  8. CD45RO+ memory T-cells produce IL-17 (show IL17A ELISA Kits) in patients with atherosclerosis.

  9. Data show the structural basis for, and the potent signaling effects of, local CD45 antigen and kinase segregation.

  10. a CD45+/CD19 (show CD19 ELISA Kits) - cell population in bone marrow aspirates correlated with the clinical outcome of patients with mantle cell lymphoma.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) interaction partners

  1. Both the number of lung CD31 (show PECAM1 ELISA Kits)-CD45-Sca-1 (show Ly6a ELISA Kits)+ cells and the expression levels of the Shh (show SHH ELISA Kits) signaling pathway were downregulated in the lung tissues of mice with pulmonary emphysema. These cells and Shh (show SHH ELISA Kits) signaling pathway are reactivated during acute adenovirus infection.

  2. the transient upregulation of IL-1beta (show IL1B ELISA Kits) and PTPRC/CD45 during the early phase as well as the increased expression of collagen type I at later stages of repair and validate the differential expression of miR (show MLXIP ELISA Kits)-204, miR (show MLXIP ELISA Kits)-205, and miR (show MLXIP ELISA Kits)-31 in skin wounds.

  3. Increased numbers of CD4 (show CD4 ELISA Kits)(+)CD45RA(-)FoxP3 (show FOXP3 ELISA Kits)(low) cells may cause an imbalance between Treg and Th17 cells that is mainly localized to the colon.

  4. Use of the common leukocyte marker CD45 increases the sensitivity of the diagnosis of lymphocytic myocarditis.

  5. Aging induces loss of stemness with concomitant gain of myogenic properties of a pure population of CD34 (show CD34 ELISA Kits)+/CD45- muscle derived stem cells.

  6. deletion of Pten in CD45-expressing cells induces development of T-cell acute lymphoblastic leukemia and lymphoma, but not other hematologic malignancies

  7. A noncatalytic role for CD45 in regulating tonic, but not antigen-mediated, B-cell antigen receptor (BCR (show BCR ELISA Kits)) signaling through modulation of the function of the inhibitory coreceptor CD22 (show CD22 ELISA Kits), was identified.

  8. CD45 ligation specifically reduced Treg motility in an integrin-dependent manner, resulting in enhanced interactions between Tregs and DCs in vivo.

  9. Data (including data from genome-wide mutagenesis studies) suggest that nonsense mutation in Ptprc is a susceptibility trait for herpes simplex encephalitis due to Herpesvirus 1; this effect appears to be mediated by Th1 (show HAND1 ELISA Kits) cells and the brain stem.

  10. These findings demonstrate a novel role for CD45 on innate immune cells in promoting lymphopenia-induced T cell proliferation and suggest that innate immune cells may communicate with stromal cells to regulate IL-7 (show IL7 ELISA Kits) production.

CD45 (PTPRC) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

Alternative names and synonyms associated with CD45 (PTPRC)

  • protein tyrosine phosphatase, receptor type, C (PTPRC) Elisa Kit
  • protein tyrosine phosphatase, receptor type, C (ptprc) Elisa Kit
  • protein tyrosine phosphatase, receptor type, C (Ptprc) Elisa Kit
  • B220 Elisa Kit
  • cd45 Elisa Kit
  • CD45R Elisa Kit
  • GP180 Elisa Kit
  • L-CA Elisa Kit
  • Lca Elisa Kit
  • loc Elisa Kit
  • Ly-5 Elisa Kit
  • LY5 Elisa Kit
  • Lyt-4 Elisa Kit
  • PTPRC Elisa Kit
  • RT7 Elisa Kit
  • si:dkeyp-47c5.1 Elisa Kit
  • T200 Elisa Kit

Protein level used designations for PTPRC

receptor-type tyrosine-protein phosphatase C , leukocyte common antigen, CD45 , protein tyrosine phosphatase, receptor type, C , CD45 antigen , leukocyte common antigen , receptor-type tyrosine-protein phosphatase C-like , T200 glycoprotein , T200 leukocyte common antigen , protein tyrosine phosphatase, receptor type, c polypeptide , lymphocyte antigen 5 , lymphocyte common antigen , Protein tyrosine phosphatase, receptor-type, c polypeptide , leucocyte common antigen , leukocyte common antigen A , leukocyte common antigen B , membrane tyrosine phosphatase

GENE ID SPECIES
386580 Gallus gallus
457607 Pan troglodytes
490255 Canis lupus familiaris
559154 Danio rerio
100026890 Monodelphis domestica
100061950 Equus caballus
100074271 Ornithorhynchus anatinus
100358807 Oryctolagus cuniculus
100446144 Pongo abelii
100474611 Ailuropoda melanoleuca
100522631 Sus scrofa
100546661 Meleagris gallopavo
5788 Homo sapiens
19264 Mus musculus
24699 Rattus norvegicus
407152 Bos taurus
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