Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Our findings provide evidence that during renal allograft rejection HLA-E along with high numbers of mismatched HLA-class I (show MICA ELISA Kits) leader peptides might represent additional targets for immune-activating responses.
The results suggest that HLA-E allelic variants may play a role in the modulation of immune responses in the context of the inability of natural conception and establishment of a viable pregnancy.
The prognostic benefit of natural killer cells, but not T-cells, is influenced by HLA-E expression in endometrial cancer.
This data reinforces the presence of only two main full-length HLA-E molecules encoded by the many HLA-E alleles detected in our population sample. In addition, this data does indicate that the distal HLA-E promoter is by far the most variable segment.
HLA-E alleles and sHLA-E levels may represent novel biomarkers for early disease progression in patients with chronic lymphocytic leukemia
In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 ELISA Kits), TLR3 (show TLR3 ELISA Kits), OAS1 (show OAS1 ELISA Kits), EIF2AK2 (show EIF2AK2 ELISA Kits), HLA-E, IFI6 (show IFI6 ELISA Kits), and STAT1 (show STAT1 ELISA Kits), showed higher expression in the islet core compared with the peri (show PLIN1 ELISA Kits)-islet area containing the surrounding immune cells
soluble HLA-Ib molecules HLA-G and HLA-E are present in BM plasma samples in physiological and pathological conditions, and their concentration correlated with stage disease in NB patients.
this study shows the high expression of HLA-E in actinic chelitis and in lip squamous cell carcinoma, which reflects the capacity that these pathologies have for evasion and progression
Our study reveals that HLA-E polymorphism is associated with nasopharyngeal cancer.
High expression of HLA-E is associated with non-small cell lung carcinoma.
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
HLA class I histocompatibility antigen, E alpha chain
, HLA class I histocompatibility antigen, alpha chain E
, MHC HLA-E alpha-1
, MHC HLA-E alpha-2.1
, MHC class I antigen E
, lymphocyte antigen