Browse our HLA Class I Histocompatibility Antigen, alpha Chain E Proteins (HLAE)

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HLA Class I Histocompatibility Antigen, alpha Chain E Proteins (HLAE)
On www.antibodies-online.com are 10 HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) Proteins from 6 different suppliers available. Additionally we are shipping HLA Class I Histocompatibility Antigen, alpha Chain E Antibodies (138) and HLA Class I Histocompatibility Antigen, alpha Chain E Kits (11) and many more products for this protein. A total of 165 HLA Class I Histocompatibility Antigen, alpha Chain E products are currently listed.
Synonyms:
EA1.2, EA2.1, HLA-6.2, MHC, QA1
list all proteins Gene Name GeneID UniProt
HLAE 3133 P13747

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Human HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) interaction partners

  1. HLA-E alleles and sHLA-E levels may represent novel biomarkers for early disease progression in patients with chronic lymphocytic leukemia

  2. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (show GBP1 Proteins), TLR3 (show TLR3 Proteins), OAS1 (show OAS1 Proteins), EIF2AK2 (show EIF2AK2 Proteins), HLA-E, IFI6 (show IFI6 Proteins), and STAT1 (show STAT1 Proteins), showed higher expression in the islet core compared with the peri (show PLIN1 Proteins)-islet area containing the surrounding immune cells

  3. soluble HLA-Ib molecules HLA-G and HLA-E are present in BM plasma samples in physiological and pathological conditions, and their concentration correlated with stage disease in NB patients.

  4. this study shows the high expression of HLA-E in actinic chelitis and in lip squamous cell carcinoma, which reflects the capacity that these pathologies have for evasion and progression

  5. Our study reveals that HLA-E polymorphism is associated with nasopharyngeal cancer.

  6. High expression of HLA-E is associated with non-small cell lung carcinoma.

  7. The positive correlation has been found between the HLA-E*01:01/01:03 A>G polymorphism, plasma HLA-E level, and advanced fibrosis stages in chronic hepatitis B patients.

  8. the promoter region of the HLA-E gene presents few and rare variable sites in Brazilian population sample.

  9. HLA-E regulates NKG2C (show KLRC2 Proteins)+ natural killer cell function through presentation of a restricted peptide repertoire

  10. HLA-E is capable of presenting a highly conserved peptide from HIV-1 capsid (AISPRTLNA) that is not recognized by NKG2A (show KLRC1 Proteins)/CD94 (show KLRD1 Proteins).

HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) Protein Profile

Protein Summary

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Alternative names and synonyms associated with HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE)

  • major histocompatibility complex, class I, E (HLA-E)
  • EA1.2 protein
  • EA2.1 protein
  • HLA-6.2 protein
  • MHC protein
  • QA1 protein

Protein level used designations for HLAE

HLA class I histocompatibility antigen, E alpha chain , HLA class I histocompatibility antigen, alpha chain E , MHC HLA-E alpha-1 , MHC HLA-E alpha-2.1 , MHC class I antigen E , lymphocyte antigen

GENE ID SPECIES
3133 Homo sapiens
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