Browse our LTA Proteins (LTA)

Full name:
Lymphotoxin-alpha Proteins (LTA)
On www.antibodies-online.com are 74 Lymphotoxin-alpha (LTA) Proteins from 22 different suppliers available. Additionally we are shipping LTA Antibodies (231) and LTA Kits (97) and many more products for this protein. A total of 411 LTA products are currently listed.
Synonyms:
hlb382, LT, LT-alpha, LT-[a], LTalpha, Ltx, LT[a], TNF-beta, TNFB, TNFSF1, Tnfsf1b
list all proteins Gene Name GeneID UniProt
LTA 16992 P09225
LTA 4049 P01374
LTA 25008 Q06332

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LTA Proteins (LTA) by Origin

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Top referenced LTA Proteins

  1. Chemical LTA Protein expressed in Escherichia coli (E. coli) - ABIN2002479 : Williams-Abbott, Walter, Cheung, Goh, Porter, Ware: The lymphotoxin-alpha (LTalpha) subunit is essential for the assembly, but not for the receptor specificity, of the membrane-anchored LTalpha1beta2 heterotrimeric ligand. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for 2002479

  2. Human LTA Protein expressed in Escherichia coli (E. coli) - ABIN667775 : Messer, Spengler, Jung, Honold, Blömer, Pape, Riethmüller, Weiss et al.: Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced ... in The Journal of experimental medicine 1991 (PubMed)
    Show all 2 references for 667775

  3. Chemical LTA Protein expressed in HEK-293 Cells - ABIN2181836 : Gray, Aggarwal, Benton, Bringman, Henzel, Jarrett, Leung, Moffat, Ng, Svedersky: Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity. in Nature 1985 (PubMed)
    Show all 2 references for 2181836

  4. Human LTA Protein expressed in Escherichia coli (E. coli) - ABIN1305059 : Paul, Ruddle: Lymphotoxin. in Annual review of immunology 1988 (PubMed)

More Proteins for LTA Interaction Partners

Mouse (Murine) Lymphotoxin-alpha (LTA) interaction partners

  1. Expression of LT alpha and beta on acinar cells in mice led to chronic pancreatitis and sufficed to reproduce key features of human autoimmune pancreatitis including the development of autoimmunity and AIP (show AIP Proteins) associated secondary extra pancreatic pathologies.

  2. These data demonstrate that lymphotoxin (show LTB Proteins)-expressing cells, such as Th1 (show HAND1 Proteins) cells, mediate stromal keratitis.

  3. TNFalpha (show TNF Proteins) and LTalpha mediate post-myocardial infarction cardiac dysfunction via TNFR1 (show TNFRSF1A Proteins) stimulation, whereas TNFR2 (show TNFRSF1B Proteins) activation is cardioprotective against ischemic injury.

  4. findings show that soluble lymphotoxin alpha (sLTalpha3) produced by RORgammat(+) innate lymphoid cells controls T cell-dependent IgA induction in the lamina propria via regulation of T cell homing to the gut (show GUSB Proteins)

  5. Data suggest that among many cytokines increased after myocardial ischemia/reperfusion (MI/R), lymphotoxin-alpha (Lta) is the only cytokine remaining elevated 24-72 h after reperfusion; LTa appears to suppress adiponectin expression following MI/R.

  6. study reports that mice deficient in lymphotoxin (show LTB Proteins), a key molecule in gut (show GUSB Proteins) immunity, were resistant to diet-induced obesity

  7. Data from lymphotoxin-alpha knockout mice suggest that lymphotoxin-alpha contributes to diet-induced weight gain and adiposity (leading to obesity) and is required to modulate accumulation of immune cells in adipose tissue (as in obesity).

  8. Grafts deficient in lymphotoxin-alpha have an attenuated capacity to induce graft-versus-host disease.

  9. Our findings suggest a contribution of lymphotoxin alpha in the control of chronic M. tuberculosis infection.

  10. The organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin alpha; however, the organization and recruitment of lymphocytes within NALT are dependent on LT alpha.

Human Lymphotoxin-alpha (LTA) interaction partners

  1. Fequencies of polymorphic allele and genotypes for the lymphotoxin-alpha gene, position +252 (rs909253), in Brazilian women with preeclampsia

  2. The allelic frequencies of LTA SNPs were found to be significantly associated with the risk of oral cancer and precancerous lesions

  3. rs909253 in LTA was identified to be significantly associated with ankylosing spondylitis susceptibility in this study population, but no significant association was found between ankylosing spondylitis risk and LTA rs2239704 or rs2229094

  4. study showed that heterozygous variant (AG) genotype of TNF-beta was associated with persistent primary immune thrombocytopenia, when compared with controls

  5. a positive correlation of HLA-DRB1 (show HLA-DRB1 Proteins)*12 and a negative correlation of HLA-DRB1 (show HLA-DRB1 Proteins)*13 with younger patientsTNFb4 allele's negative association with older patients displaying higher PSA (show PLAG1 Proteins) levels, higher GS and positive surrounding tissue involvement; positive association of TNFb5 allele for both older and younger patients

  6. the present study suggests LTa +252G as a risk alleles for disease susceptibility associated with higher serum levels of LTa and concomitant discrete clinical features among Indian systemic lupus erythematosus patients in India

  7. this study shows that TNF (show TNF Proteins)-b is elevated in wound exudates of patients with hidradenitis suppurativa

  8. LTA -804C/A gene polymorphism is not found to be associated with the susceptibility of ischemic stroke in both Asian as well as in Caucasian population.

  9. After multivariable analysis TNF-alpha (show TNF Proteins) polymorphism showed no consistent association with leukemia. CONCLUSIONS: This meta-analysis suggests that the LT-alpha +252 AA polymorphism is associated with the risk of leukemia

  10. Tumor Necrosis Factor (show TNF Proteins) and Lymphotoxin (show LTB Proteins) in Regulation of Intestinal Inflammation.

LTA Protein Profile

Protein Summary

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with LTA

  • lymphotoxin A (Lta)
  • lymphotoxin alpha (LTA)
  • lymphotoxin alpha (Lta)
  • lymphotoxin alpha (TNF superfamily, member 1) (LTA)
  • hlb382 protein
  • LT protein
  • LT-alpha protein
  • LT-[a] protein
  • LTalpha protein
  • Ltx protein
  • LT[a] protein
  • TNF-beta protein
  • TNFB protein
  • TNFSF1 protein
  • Tnfsf1b protein

Protein level used designations for Lymphotoxin-alpha Proteins (LTA)

TNF beta , lymphotoxin alpha , lymphotoxin-alpha , tumor necrosis factor ligand superfamily member 1 , LT-alpha , TNF superfamily, member 1 , TNF-beta , tumor necrosis factor beta , lymphotoxin A , lymphotoxin alpha (TNF superfamily, member 1) , Lymphotoxin-alpha , tumour necrosis factor beta , ATP-binding cassette, sub-family F (GCN20), member 1

GENE ID SPECIES
16992 Mus musculus
4049 Homo sapiens
25008 Rattus norvegicus
607183 Canis lupus familiaris
280845 Bos taurus
407742 Sus scrofa
100328931 Oryctolagus cuniculus
101123078 Ovis aries
494185 Pan troglodytes
715425 Macaca mulatta
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