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Copy number variations of HLA-I and activation of NKp30 pathway determine the sensitivity of gastric cancer cells to the cytotoxicity of natural killer cells
Data suggest that NK cells and NKp30 could play a role in Antisynthetase syndrome pathogenesis.
the stalk domains of NKp30 and NKp46 (show NCR1 ELISA Kits), another NCR employing CD3zeta (show CD247 ELISA Kits) for signaling, were not exchangeable without drastic deficiencies in folding, plasma membrane targeting, and/or ligand-induced receptor signaling.
Age and CMV serostatus influence the expression of NKp30, NKp46 (show NCR1 ELISA Kits) and DNAM-1 (show CD226 ELISA Kits) activating receptors on resting and IL-2 (show IL2 ELISA Kits) activated natural killer cells.
NKp30-B7-H6 (show NCR3LG1 ELISA Kits) interaction is a novel cell contact mechanism that mediates activation of Group 2 innate lymphoid cells and identifies a potential target for the development of novel therapeutics for atopic dermatitis and other atopic diseases.
Our results suggest that NKP30-B7-H6 (show NCR3LG1 ELISA Kits) interaction can aggravate hepatocyte damage, probably through up-regulation of IL-32 (show IL32 ELISA Kits) expression in hepatitis B virus-related acute-on-chronic liver failure
the interaction between NKp30 and B7-H6 (show NCR3LG1 ELISA Kits) may contribute to the fate of neuroblastoma (show ARHGEF16 ELISA Kits) patients
Suggest role for NKp30 isoforms in influencing liver damage and ensuing fibrosis in chronic hepatitis C infection.
show that in addition to NKG2D (show KLRK1 ELISA Kits), human CEACAM1 (show CEACAM1 ELISA Kits) can inhibit NK-cell activation via NKp30 or 2B4 (show CD244 ELISA Kits)
Up-regulation of DNAM-1 (show CD226 ELISA Kits) and NKp30, associated with improvement of NK cells activation after long-term culture of mononuclear cells from patients with ovarian neoplasms.
phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 ELISA Kits), NKp30 NKp80 (show KLRF1 ELISA Kits), and NKG2D (show KLRK1 ELISA Kits); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 (show KLRF1 ELISA Kits) and particularly NKp30
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
natural cytotoxicity triggering receptor 3
, activating NK-A1 receptor
, activating natural killer receptor p30
, lymphocyte antigen 117
, natural killer cell p30-related protein
, NK receptor 1c7
, natural killer cell p30-related