Browse our anti-Nucleoside Phosphorylase (NP) Antibodies

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anti-Nucleoside Phosphorylase Antibodies (NP)
On are 54 Nucleoside Phosphorylase (NP) Antibodies from 13 different suppliers available. Additionally we are shipping Nucleoside Phosphorylase Proteins (13) and Nucleoside Phosphorylase Kits (2) and many more products for this protein. A total of 72 Nucleoside Phosphorylase products are currently listed.
AL024301, AU015798, fc27g06, NP, Np-1, Np-2, Pnp1, PRO1837, PUNP, wu:fc27g06, wu:fd51h11, zgc:77008
list all antibodies Gene Name GeneID UniProt
NP 290029  
NP 4860 P00491
NP 18950 P23492

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Most Popular Reactivities for anti-Nucleoside Phosphorylase (NP) Antibodies

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Top referenced anti-Nucleoside Phosphorylase Antibodies

  1. Human Polyclonal NP Primary Antibody for IHC, IHC (p) - ABIN4348699 : Kojima, Chiyomaru, Kawakami, Yoshino, Enokida, Nohata, Fuse, Ichikawa, Naya, Nakagawa, Seki: Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. in British journal of cancer 2012 (PubMed)

More Antibodies against Nucleoside Phosphorylase Interaction Partners

Cow (Bovine) Nucleoside Phosphorylase (NP) interaction partners

  1. the biological role of packing of the PNP monomers into a trimeric structure

  2. crystal structure complexed with analogs of the inhibitor 2-diaminopurine aglycone (purine nucleoside phosphorylase)

  3. PNP purine nucleoside phosphorylase was crystallized in space group P2(1)2(1)2(1) in the presence of (S)-PMPDAP and phosphate, and the resulting structure of the binary PNP/(S)-PMPDAP complex was refined at 2.05A resolution.

  4. alf (show GTF2A1L Antibodies) spleen enzyme is a homotrimer and previous suggestions for dissociation of this enzyme into more active monomers, upon dilution of the enzyme or addition of phosphate, are incorrect.

  5. PCR amplification of the calf phosphorylase from the calf spleen library, cloning, overexpression of the recombinant PNP, its enzymatic activity and interactions with typical ligands of mammalian wild type PNP are described.

  6. The transition-state structure of triple mutant PNP is altered as a consequence of the amino acids in the second sphere from the catalytic site.

Human Nucleoside Phosphorylase (NP) interaction partners

  1. Data show that the mutations in purine nucleoside phosphorylase (PNP) alters the enthalpy-entropy balance with little effect on the catalytic rates.

  2. Data (including data from empirical valence bond/molecular dynamic simulations) suggest that PNP substrate specificity for inosine and guanosine is a direct result of electrostatic preorganization energy along the reaction coordinate.

  3. the binding mechanism of a transition state analogue (DADMe-immucillin-H) to the purine nucleoside phosphorylase (PNP) enzyme, is reported.

  4. Data show that [15N, 2H]His8-purine nucleoside phosphorylase (PNP) had reduced catalytic site chemistry larger than proportional to the enzymatic mass difference.

  5. Study of genetic heterogeneity in systemic lupus erythematosus, the top associations in European ancestry were protein kinase (show CDK7 Antibodies), cyclic GMP (show NT5C2 Antibodies)-dependent, type I (PRKG1 (show PRKG1 Antibodies)) rs7897633 (P(Meta) = 2.75 x 10(-8)) and purine nucleoside phosphorylase (PNP) rs1049564 (P(Meta) = 1.24 x 10(-7)).

  6. Human small intestine is a key site for ribavirin phosphorolysis and that PNP is primarily involved in the metabolism.

  7. Complete lack of PNP triggers accumulation of deoxyguanosine, thereby disrupting B-cell development, the consequence of which is more profound with time, as was found in the older sister.

  8. Biochemical and genetic data on a cohort of seven patients from six families identified as PNPase (show PNPT1 Antibodies) deficient, is reported.

  9. This study for the first time describes elevated levels of alpha synuclein (show SNCA Antibodies) in pancreatic adenocarcinoma as well as highlights the potential of evaluating NP protein expression.

  10. investigation of catalytic mechanisms involved in catalysis by PNP: transition states in arsenolysis and phosphorolysis

Mouse (Murine) Nucleoside Phosphorylase (NP) interaction partners

  1. PNP deficiency causes cerebellar abnormalities, including Purkinje cell damage and progressive motor deficits.

  2. PNP is important for the survival of DP thymocytes. Accumulation of dGuo in cases of PNP deficiency leads to mitochondria-initiated apoptosis of DP thymocytes, which can be prevented by restoring PNP activity in the cells.

Nucleoside Phosphorylase (NP) Antigen Profile

Antigen Summary

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Alternative names and synonyms associated with Nucleoside Phosphorylase (NP)

  • purine nucleoside phosphorylase 5a (pnp5a) antibody
  • diacylglycerol kinase, eta (DGKH) antibody
  • purine nucleoside phosphorylase (Pnp) antibody
  • purine nucleoside phosphorylase (PNP) antibody
  • purine-nucleoside phosphorylase (Pnp) antibody
  • AL024301 antibody
  • AU015798 antibody
  • fc27g06 antibody
  • NP antibody
  • Np-1 antibody
  • Np-2 antibody
  • Pnp1 antibody
  • PRO1837 antibody
  • PUNP antibody
  • wu:fc27g06 antibody
  • wu:fd51h11 antibody
  • zgc:77008 antibody

Protein level used designations for NP

inosine phosphorylase , inosine-guanosine phosphorylase , nucleoside phosphorylase , purine-nucleoside:orthophosphate ribosyltransferase , purine nucleoside phosphorylase , purine-nucleoside phosphorylase 1

791647 Danio rerio
537533 Bos taurus
290029 Rattus norvegicus
4860 Homo sapiens
493724 Bos taurus
475393 Canis lupus familiaris
769958 Gallus gallus
100718329 Cavia porcellus
100157138 Sus scrofa
18950 Mus musculus
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