Browse our anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies

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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies (ABCB4)
On www.antibodies-online.com are 54 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies from 16 different suppliers available. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Proteins (16) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Kits (9) and many more products for this protein. A total of 84 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 products are currently listed.
Synonyms:
ABC20, ABC21, ABCB1, Abcb4, ABCB4a, CMDR1, Evi32, GBD1, GP170, ICP3, mdr-2, mdr-3, MDR1, Mdr1a, Mdr2, MDR2/3, MDR3, P-gp, PFIC-3, Pgp, PGP2, PGP3, Pgy-2, Pgy-3, PGY1, Pgy2, Pgy3, zgc:172149
list all antibodies Gene Name GeneID UniProt
ABCB4 18671 P21447
ABCB4 5244 P21439
ABCB4 24891 Q08201

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Most Popular Reactivities for anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies

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anti-Rat (Rattus) Antibodies:

All available anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies

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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies

  1. Human Polyclonal ABCB4 Primary Antibody for IHC (p), WB - ABIN390060 : Ruetz, Gros: Phosphatidylcholine translocase: a physiological role for the mdr2 gene. in Cell 1994 (PubMed)
    Show all 2 references for 390060

  2. Human Monoclonal ABCB4 Primary Antibody for IHC (fro), IF - ABIN1105159 : Peng, Yanagida, Chen, Han: Ellipsoidal TiO2 hierarchitectures with enhanced photovoltaic performance. in Chemistry (Weinheim an der Bergstrasse, Germany) 2012 (PubMed)
    Show all 2 references for 1105159

  3. Cow (Bovine) Polyclonal ABCB4 Primary Antibody for WB - ABIN2776967 : Floreani, Carderi, Paternoster, Soardo, Azzaroli, Esposito, Montagnani, Marchesoni, Variola, Rosa Rizzotto, Braghin, Mazzella: Hepatobiliary phospholipid transporter ABCB4, MDR3 gene variants in a large cohort of Italian women with intrahepatic cholestasis of pregnancy. in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2008 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Interaction Partners

Zebrafish ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. Zebrafish Abcb4 plays crucial roles in cellular efflux of microcystin-LR and is a potential molecular marker for the monitoring of cyanobacteria contamination in the aquatic environment.

Rabbit ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. In the rabbit cornea, the expression and activity of MDR1 transporter was confirmed, whereas human cell culture models and porcine corneas did not show MDR1 expression

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. multiple pathways, including MMP9 (show MMP9 Antibodies) cleavage and ubiquitinylation, mediated P-gp downmodulation.

  2. Data suggest that MDR3 isoforms, both human and mouse isoforms, exhibit different affinities for fluorescent dyes and drugs; thus, ligands likely occupy partially overlapping but distinct binding sites.

  3. using double electron-electron resonance and molecular dynamics simulations to describe the ATP- and substrate-coupled conformational cycle of the mouse ABC (show ABCB6 Antibodies) efflux transporter P-glycoprotein (Pgp; also known as ABCB1 (show ABCB1 Antibodies))

  4. Mdr1a deficiency significantly enhanced the analgesic effect of aconitine and exacerbated its toxicity in the brain.

  5. Chrysosplenetin inhibited P-gp activity and reverse the up-regulated P-gp and MDR1 levels induced by artemisinin.

  6. Tamsulosin and tolterodine with P-gp gene expression and activity in an enantiomer-specific way.

  7. These results indicate that nilotinib reverses P-gp- mediated MDR by blocking the efflux function and potentiates DOX-induced cardiotoxicity.

  8. Results indicate that Abeta (show APP Antibodies) accumulates to a greater degree in brains of mice lacking MDR1A

  9. [(18)F]Mefway is modulated by P-gp, and not by Bcrp (show ABCG2 Antibodies) in rodents.

  10. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. results are suggestive of a potential downstream molecular effect for the described polymorphisms on the expression pattern of the ABCB4 underlining the importance of synonymous variants

  2. the first characterisation at the protein level of six ABCB4 variants (D243A, K435T, G535D, I490T, R545C, and S978P) previously found in patients with inflammatory liver diseases or liver cancer, is reported.

  3. Ivacaftor is a potential therapy for selected patients with cystic fibrosis (show S100A8 Antibodies) with mutations of ABCB4.

  4. Data show that patients with low multidrug resistance protein 3 (MDR3) expression were significantly associated with a better outcome than patients with high MDR3 expression.

  5. In patients with intrahepatic cholestasis of pregnancy, ABCB4 gene mutation was not associated with response to ursodeoxycholic acid treatment.

  6. Data suggest that MDR3 isoforms, both human and mouse isoforms, exhibit different affinities for fluorescent dyes and drugs; thus, ligands likely occupy partially overlapping but distinct binding sites.

  7. Single-nucleotide polymorphism in ABCB4 gene is associated with gallbladder cancer.

  8. the cholestatic potential of certain drugs may be aggravated by simultaneous inhibition of BSEP (show ABCB11 Antibodies) and MDR3.

  9. Negative immunoreaction of MDR3 was found in the majority of the progressive familial intrahepatic cholestasis (PFIC (show ATP8B1 Antibodies)) group. Nonetheless, the negative immunoreaction was demonstrated in a considerable number of the non-PFIC (show ATP8B1 Antibodies) group. Negative MDR3 immunoreaction was more frequently associated with PFIC3 compared to non-PFIC (show ATP8B1 Antibodies) group.

  10. Exons 6, 8 and 9 mutations of ABCB4 gene are not common among Egyptian children with Progressive Familial Intrahepatic Cholestasis type 3.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antigen Profile

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined\; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

Alternative names and synonyms associated with ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)

  • ATP-binding cassette, sub-family B (MDR/TAP), member 5 (abcb5) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1-like B (ABCB1LB) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1-like A (ABCB1LA) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (abcb4) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (Abcb4) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 4 (Abcb4) antibody
  • ABC20 antibody
  • ABC21 antibody
  • ABCB1 antibody
  • Abcb4 antibody
  • ABCB4a antibody
  • CMDR1 antibody
  • Evi32 antibody
  • GBD1 antibody
  • GP170 antibody
  • ICP3 antibody
  • mdr-2 antibody
  • mdr-3 antibody
  • MDR1 antibody
  • Mdr1a antibody
  • Mdr2 antibody
  • MDR2/3 antibody
  • MDR3 antibody
  • P-gp antibody
  • PFIC-3 antibody
  • Pgp antibody
  • PGP2 antibody
  • PGP3 antibody
  • Pgy-2 antibody
  • Pgy-3 antibody
  • PGY1 antibody
  • Pgy2 antibody
  • Pgy3 antibody
  • zgc:172149 antibody

Protein level used designations for ABCB4

ATP-binding cassette, sub-family B (MDR/TAP), member 4 , ATP-binding cassette, subfamily B, member 4 , ABC transporter protein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B, member 1 , member 1 , member 4 , multidrug resistance protein 1 , sub-family B (MDR/TAP) , subfamily B , P glycoprotein 3/ multiple drug resistance 3 , ABC efflux transporter 4 , abcb1b , multidrug resistance protein 3-like , multidrug resistance protein 3 , ATP-binding cassette transporter protein , multi-drug resistance P-glycoprotein 1 , ATP-binding cassette sub-family B member 1A , ATP-binding cassette, subfamily B, member 1A , P glycoprotein 3 , P-glycoprotein 3 , ecotropic viral integration site 32 , multi-drug resistance 3 , multidrug resistance protein 1A , multiple drug resistant 1a , P-glycoprotein 2 , multidrug resistance protein 2 , ATP-binding cassette sub-family B member 4 , P glycoprotein 3/multiple drug resistance 3 , P-glycoprotein-3/multiple drug resistance-3 , multiple drug resistance 3 , P glycoprotein 2 , multidrug resistance 3 , p-glycoprotein isoform III , ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2 , ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2) , ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein 3/ multidrug resistance 2) , P-glycoprotein 3/ multidrug resistance 2

GENE ID SPECIES
394865 Xenopus (Silurana) tropicalis
395712 Gallus gallus
420534 Gallus gallus
748364 Pan troglodytes
756756 Strongylocentrotus purpuratus
783154 Bos taurus
100136865 Danio rerio
100354947 Oryctolagus cuniculus
100398854 Callithrix jacchus
100455534 Pongo abelii
100462975 Monodelphis domestica
100475375 Ailuropoda melanoleuca
100008914 Oryctolagus cuniculus
18671 Mus musculus
100682537 Cricetulus griseus
5244 Homo sapiens
18670 Mus musculus
482284 Canis lupus familiaris
100144586 Sus scrofa
100336338 Bos taurus
100682535 Cricetulus griseus
24891 Rattus norvegicus
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