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Browse our anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies

Full name:
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies (ABCB4)
On www.antibodies-online.com are 67 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies from 15 different suppliers available. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Proteins (17) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Kits (7) and many more products for this protein. A total of 96 ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 products are currently listed.
Synonyms:
ABC20, ABC21, ABCB1, Abcb4, ABCB4a, CMDR1, Evi32, GBD1, GP170, ICP3, mdr-2, mdr-3, MDR1, Mdr1a, Mdr2, MDR2/3, MDR3, P-gp, PFIC-3, Pgp, PGP2, PGP3, Pgy-2, Pgy-3, PGY1, Pgy2, Pgy3, zgc:172149
list all antibodies Gene Name GeneID UniProt
ABCB4 18671 P21447
ABCB4 5244 P21439
ABCB4 24891 Q08201

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Most Popular Reactivities for anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antibodies

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All available anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies

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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Antibodies

  1. Human Polyclonal ABCB4 Primary Antibody for IHC (p), WB - ABIN390060 : Ruetz, Gros: Phosphatidylcholine translocase: a physiological role for the mdr2 gene. in Cell 1994 (PubMed)
    Show all 2 references for ABIN390060

  2. Human Monoclonal ABCB4 Primary Antibody for IHC (fro), IF - ABIN1105159 : Peng, Yanagida, Chen, Han: Ellipsoidal TiO2 hierarchitectures with enhanced photovoltaic performance. in Chemistry (Weinheim an der Bergstrasse, Germany) 2012 (PubMed)
    Show all 2 references for ABIN1105159

  3. Cow (Bovine) Polyclonal ABCB4 Primary Antibody for WB - ABIN2776966 : Floreani, Carderi, Paternoster, Soardo, Azzaroli, Esposito, Montagnani, Marchesoni, Variola, Rosa Rizzotto, Braghin, Mazzella: Hepatobiliary phospholipid transporter ABCB4, MDR3 gene variants in a large cohort of Italian women with intrahepatic cholestasis of pregnancy. in Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2008 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 Interaction Partners

Zebrafish ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. Zebrafish Abcb4 plays crucial roles in cellular efflux of microcystin-LR and is a potential molecular marker for the monitoring of cyanobacteria contamination in the aquatic environment.

Rabbit ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. In the rabbit cornea, the expression and activity of MDR1 transporter was confirmed, whereas human cell culture models and porcine corneas did not show MDR1 expression

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. Chrysosplenetin inhibited P-gp activity and reverse the up-regulated P-gp and MDR1 levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp gene expression and activity in an enantiomer-specific way.

  3. These results indicate that nilotinib reverses P-gp- mediated MDR by blocking the efflux function and potentiates DOX-induced cardiotoxicity.

  4. Results indicate that Abeta (show APP Antibodies) accumulates to a greater degree in brains of mice lacking MDR1A

  5. [(18)F]Mefway is modulated by P-gp, and not by Bcrp (show ABCG2 Antibodies) in rodents.

  6. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  7. Analysis regulator effects analysis, showed that curcumin's antiinflammatory activity in Mdr1a(-/-) mouse colon may be mediated by activation of alpha-catenin (show CTNNA1 Antibodies), which has not previously been reported

  8. mdr1a-siRNA mediated inhibition of Mdr1a expression markedly elevates serum levels and increases the hepatic exposure to triptolide.

  9. Data suggest that activities of human ABCB1 (show ABCB1 Antibodies) and mouse Abcb1a/Mdr1a are unaltered (that is, efflux of fluorescent dyes is unaltered) in chimeric forms created by exchange of homologous transmembrane/nucleotide-binding domains of ABCB1 (show ABCB1 Antibodies) and Abcb1a/Mdr1a.

  10. Findings imply a close link between Mdr2 (-/-) -associated tumorigenesis and perturbation of these biological processes and suggest potential extrahepatic functions of Mdr2.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) interaction partners

  1. Negative immunoreaction of MDR3 was found in the majority of the progressive familial intrahepatic cholestasis (PFIC (show ATP8B1 Antibodies)) group. Nonetheless, the negative immunoreaction was demonstrated in a considerable number of the non-PFIC (show ATP8B1 Antibodies) group. Negative MDR3 immunoreaction was more frequently associated with PFIC3 compared to non-PFIC (show ATP8B1 Antibodies) group.

  2. Exons 6, 8 and 9 mutations of ABCB4 gene are not common among Egyptian children with Progressive Familial Intrahepatic Cholestasis type 3.

  3. Case Report: novel ABCB4 mutation in mother and daughter with progressive familial intrahepatic cholestasis 3.

  4. ABCB4 mutation causing progressive familial intrahepatic cholestasis 3 in two brothers, and intrahepatic cholestasis of pregnancy in their mother is described.

  5. A mutant ABCB4 genotype is related to the clinical expression of cholestatic liver disease.

  6. There are varying effects of ABCB4 missense mutations but even a modest reduction in MDR3 activity may contribute or predispose to the onset of Cholestatic liver disease in the pediatric age.

  7. A mutation of ABCB4 protein as a cause of liver disease

  8. most severe phenotypes appreciated by the duration of transplant-free survival were caused by ABCB4 variants that were markedly retained in the endoplasmic reticulum and expressed in a homozygous status

  9. Report highly specific expression of BSEP (show ABCB11 Antibodies) and MDR3 in hepatocellular carcinoma.

  10. Interaction of ABCB4 with EBP50 (show SLC9A3R1 Antibodies) through its PDZ (show INADL Antibodies)-like motif plays a critical role in the regulation of ABCB4 expression and stability at the canalicular plasma membrane.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4) Antigen Profile

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined\; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

Alternative names and synonyms associated with ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)

  • ATP-binding cassette, sub-family B (MDR/TAP), member 5 (abcb5) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1-like B (ABCB1LB) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1-like A (ABCB1LA) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (abcb4) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (Abcb4) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 4 (Abcb4) antibody
  • ABC20 antibody
  • ABC21 antibody
  • ABCB1 antibody
  • Abcb4 antibody
  • ABCB4a antibody
  • CMDR1 antibody
  • Evi32 antibody
  • GBD1 antibody
  • GP170 antibody
  • ICP3 antibody
  • mdr-2 antibody
  • mdr-3 antibody
  • MDR1 antibody
  • Mdr1a antibody
  • Mdr2 antibody
  • MDR2/3 antibody
  • MDR3 antibody
  • P-gp antibody
  • PFIC-3 antibody
  • Pgp antibody
  • PGP2 antibody
  • PGP3 antibody
  • Pgy-2 antibody
  • Pgy-3 antibody
  • PGY1 antibody
  • Pgy2 antibody
  • Pgy3 antibody
  • zgc:172149 antibody

Protein level used designations for ABCB4

ATP-binding cassette, sub-family B (MDR/TAP), member 4 , ATP-binding cassette, subfamily B, member 4 , ABC transporter protein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B, member 1 , member 1 , member 4 , multidrug resistance protein 1 , sub-family B (MDR/TAP) , subfamily B , P glycoprotein 3/ multiple drug resistance 3 , ABC efflux transporter 4 , abcb1b , multidrug resistance protein 3-like , multidrug resistance protein 3 , ATP-binding cassette transporter protein , multi-drug resistance P-glycoprotein 1 , ATP-binding cassette sub-family B member 1A , ATP-binding cassette, subfamily B, member 1A , P glycoprotein 3 , P-glycoprotein 3 , ecotropic viral integration site 32 , multi-drug resistance 3 , multidrug resistance protein 1A , multiple drug resistant 1a , P-glycoprotein 2 , multidrug resistance protein 2 , ATP-binding cassette sub-family B member 4 , P glycoprotein 3/multiple drug resistance 3 , P-glycoprotein-3/multiple drug resistance-3 , multiple drug resistance 3 , P glycoprotein 2 , multidrug resistance 3 , p-glycoprotein isoform III , ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2 , ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2) , ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein 3/ multidrug resistance 2) , P-glycoprotein 3/ multidrug resistance 2

GENE ID SPECIES
394865 Xenopus (Silurana) tropicalis
395712 Gallus gallus
420534 Gallus gallus
748364 Pan troglodytes
756756 Strongylocentrotus purpuratus
783154 Bos taurus
100136865 Danio rerio
100354947 Oryctolagus cuniculus
100398854 Callithrix jacchus
100455534 Pongo abelii
100462975 Monodelphis domestica
100475375 Ailuropoda melanoleuca
100008914 Oryctolagus cuniculus
18671 Mus musculus
100682537 Cricetulus griseus
5244 Homo sapiens
18670 Mus musculus
482284 Canis lupus familiaris
100144586 Sus scrofa
100336338 Bos taurus
100682535 Cricetulus griseus
24891 Rattus norvegicus
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