Browse our anti-Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM) Antibodies

Full name:
anti-Acyl-Coenzyme A Dehydrogenase, Medium Chain Antibodies (ACADM)
On www.antibodies-online.com are 2 Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM) Antibodies from 2 different suppliers available. A total of 2 Acyl-Coenzyme A Dehydrogenase, Medium Chain products are currently listed.
Synonyms:
ACAD1, AU018656, MCAD, MCADH
list all antibodies Gene Name GeneID UniProt
ACADM 34 P11310
ACADM 24158 P08503
ACADM 11364 P45952

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More Antibodies against Acyl-Coenzyme A Dehydrogenase, Medium Chain Interaction Partners

Human Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM) interaction partners

  1. Exclusively breastfed neonates with MCAD are at risk for early metabolic decompensation. As breastfeeding rates increase, close management of feeding difficulties is essential for all neonates awaiting newborn screening results

  2. The in silico structural changes in medium-chain acyl-CoA dehydrogenase (hMCAD) p.K329E variant protein affect the disturbed oligomeric profile, thermal stability, and conformational flexibility, with respect to the wild-type.

  3. LCHAD (show HADHA Antibodies) and MCAD are differentially expressed in maternal and fetal tissues during normal late pregnancy, which may represent a metabolic adaptation in response to physiological maternal dyslipidemia during late pregnancy.

  4. Study determined three mutations (p.R53C, p.R281S and p.G362E) in MCAD protein predisposing for MCAD deficiency which seems to be unique to Japanese population.

  5. our study demonstrates that not all mutations identified in children with abnormal NBS (show NBN Antibodies) profiles suggestive of MCAD deficiency result in a total loss in MCAD activity and function

  6. mutations in the ACADM gene lower the temperature threshold at which medium-chain acyl-CoA dehydrogenase deficiency loss-of-function occurs.

  7. Segregation studies in the Gypsy families showed that 93/123 relatives were carriers of the acyl-coenzyme A (show SOAT2 Antibodies) dehydrogenase G985 allele, suggesting its high prevalence in this ethnic group.

  8. Identify an ACADM founder mutation for MCADD in Saudi Arabian population.

  9. This supports that c.1161A>G is a functional SNP, which leads to higher MCAD expression, perhaps due to improved splicing. This study is a proof of principle that synonymous SNPs are not neutral.

  10. medium chain acyl-CoA dehydrogenase involve in the metabolism of phenylbutyrate.

Mouse (Murine) Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM) interaction partners

  1. the transcriptional regulatory circuits involved in the control of MCAD gene expression under hypoxic conditions are modulated by upstream factors that are sensitive to the levels of oxygen

  2. MCAD is reduced in liver, heart & kidney in lipopolysaccharide-induced acute phase response; binding liver nuclear extracts to ERRalpha (show ESRRA Antibodies) response element found in promoter region of MCAD was decreased during APR (show PMAIP1 Antibodies), suggesting less transcription of MCAD

  3. The MCAD-/- mice developed an organic aciduria and fatty liver, and showed profound cold intolerance at 4 degrees C with prior fasting.

  4. MCAD deficiency in mice leads to specific changes in hepatic carbohydrate management on exposure to metabolic stress.

  5. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes (MCAD/citrate synthase (show CS Antibodies)) without affecting development of heart failure with pressure overload.

Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM) Antigen Profile

Antigen Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Acyl-Coenzyme A Dehydrogenase, Medium Chain (ACADM)

  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (Acadm) antibody
  • acyl-Coenzyme A dehydrogenase, medium chain (Acadm) antibody
  • ACAD1 antibody
  • AU018656 antibody
  • MCAD antibody
  • MCADH antibody

Protein level used designations for ACADM

acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain , medium-chain specific acyl-CoA dehydrogenase, mitochondrial , Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain , Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain , acyl-Coenzyme A dehydrogenase, medium chain , medium-chain acyl-CoA dehydrogenase

GENE ID SPECIES
34 Homo sapiens
24158 Rattus norvegicus
11364 Mus musculus
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