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Human Polyclonal GRHL1 Primary Antibody for ICC, IF - ABIN4316149
Gao, Vockley, Pauli, Newberry, Xue, Randell, Reddy, Hogan: Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium.[corrected]. in Proceedings of the National Academy of Sciences of the United States of America 2013
Human Polyclonal GRHL1 Primary Antibody for ICC, IF - ABIN4316148
Tran, Kennedy, Leon Carrion, Bodreddigari, Goodwin, Sutter, Sutter: EGFR regulation of epidermal barrier function. in Physiological genomics 2012
BMP4 (show BMP4 Antibodies)-dependent expression of Xenopus Grainyhead-like 1 has a critical role in epidermal differentiation
All of these processes involve epithelial-mesencyhmal transition (EMT (show ITK Antibodies)), MET or a sequence of both, suggesting that the GRHL (show GHRL Antibodies) factors((GRHL1, GRHL2 (show GRHL2 Antibodies) and GRHL3 (show GRHL3 Antibodies)), could potentially affect tumor initiation and progression via EMT (show ITK Antibodies)
it was observed that ER stimulated gene expression by interacting with MEIS1 (show MEIS1 Antibodies) and FOXP3 (show FOXP3 Antibodies), and ER inhibited gene expression by interacting with THRB (show THRB Antibodies) and GRHL1.
Grhl1 deficiency affects inner ear development in zebrafish.
GRHL1, GRHL2 (show GRHL2 Antibodies), and GRHL3 (show GRHL3 Antibodies) have roles in cellular proliferation, differentiation, adhesion, and polarity and may promote cancer or be tumor suppressors [review]
Downregulation of miR122 by grainyhead-like 2 (show GRHL2 Antibodies) restricts the hepatocytic differentiation potential of adult liver progenitor cells.
A significant role for HDAC3 (show HDAC3 Antibodies) in the MYCN (show MYCN Antibodies)-mediated repression of GRHL1.
Our findings reveal important pathophysiological differences between human pulmonary fibrosis and specific mouse models of fibrosis and support a crucial role of GRHL2 (show GRHL2 Antibodies) in epithelial activation in lung fibrosis and perhaps also in epithelial plasticity.
LBP-1b (show UBP1 Antibodies) and LBP-9 (show TFCP2L1 Antibodies) both stimulate LBP-32/MGR promoter activity.
Includes a comparison to TFCP2L2, the GRHL1 protein.
Significant changes in blood pressure were observed in mice lacking the GRHl1 gene following high and low sodium diet.
No involvement of Grhl1 in blood pressure regulation, but Grhl1 expression influences the regulation of heart rate.
Grainyhead like 1 is a transcriptional regulator that may perform important functions in epithelial tissues of mammals and is epidermally expressed
Grhl (show GHRL Antibodies) genes are highly expressed in the developing epidermis.
Important regulator of the desmoglein 1 (show DSG1 Antibodies) genes in the context of hair anchorage and epidermal differentiation.
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein can exist as a homodimer or can form heterodimers with sister-of-mammalian grainyhead or brother-of-mammalian grainyhead. This protein functions as a transcription factor during development.
, grainyhead-like protein 1 homolog
, grainyhead-like-1 protein
, transcription factor CP2-like 2
, LBP protein 32
, mammalian grainyhead
, transcription factor LBP-32
, grainyhead like 1
, p61 MGR
, p70 MGR
, DNA methyltransferase 3A