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Browse our anti-Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Antibodies

Full name:
anti-Sterol Regulatory Element Binding Transcription Factor 2 Antibodies (SREBF2)
On www.antibodies-online.com are 88 Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Antibodies from 22 different suppliers available. Additionally we are shipping Sterol Regulatory Element Binding Transcription Factor 2 Proteins (10) and Sterol Regulatory Element Binding Transcription Factor 2 Kits (7) and many more products for this protein. A total of 111 Sterol Regulatory Element Binding Transcription Factor 2 products are currently listed.
Synonyms:
AI608257, bHLHd2, lop13, nuc, SREBF2, Srebf2_retired, SREBP-2, SREBP2, SREBP2gc, zgc:158371
list all antibodies Gene Name GeneID UniProt
SREBF2 20788 Q3U1N2
SREBF2 6721 Q12772
SREBF2 300095 Q3T1I5

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All available anti-Sterol Regulatory Element Binding Transcription Factor 2 Antibodies

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Top referenced anti-Sterol Regulatory Element Binding Transcription Factor 2 Antibodies

  1. Chicken Monoclonal SREBF2 Primary Antibody for ELISA, GS - ABIN4355936 : Janowski, Shan, Russell: The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols. in The Journal of biological chemistry 2001 (PubMed)
    Show all 14 references for ABIN4355936

  2. Human Polyclonal SREBF2 Primary Antibody for ICC, IF - ABIN261631 : Huster, Purnat, Burkhead, Ralle, Fiehn, Stuckert, Olson, Teupser, Lutsenko: High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease. in The Journal of biological chemistry 2007 (PubMed)
    Show all 6 references for ABIN261631

  3. Human Polyclonal SREBF2 Primary Antibody for EIA, IF - ABIN954950 : Gerin, Clerbaux, Haumont, Lanthier, Das, Burant, Leclercq, MacDougald, Bommer: Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN954950

  4. Human Monoclonal SREBF2 Primary Antibody for IP, WB - ABIN967564 : Hua, Sakai, Ho, Goldstein, Brown: Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN967564

  5. Human Polyclonal SREBF2 Primary Antibody for IF, IHC (p) - ABIN654630 : Marquart, Allen, Ory, Baldán: miR-33 links SREBP-2 induction to repression of sterol transporters. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for ABIN654630

  6. Human Monoclonal SREBF2 Primary Antibody for ChIP, WB - ABIN2668815 : Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment. in PLoS ONE 2014 (PubMed)

  7. Human Polyclonal SREBF2 Primary Antibody for IP, WB - ABIN4355938 : Karanth, Tran, Kuberan, Schlegel: Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice. in Disease models & mechanisms 2013 (PubMed)

  8. Chicken Polyclonal SREBF2 Primary Antibody for WB - ABIN2792226 : Zeng, Liao, Liu, Lee, Zhu, Wang, Stemerman, Zhu, Shyy: Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against Sterol Regulatory Element Binding Transcription Factor 2 Interaction Partners

Mouse (Murine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. SIRT1 (show SIRT1 Antibodies) gene knock-out may aggravate cartilage degeneration in osteoarthritis by activating the SREBP2 protein-mediated PI3K/AKT (show AKT1 Antibodies) signalling pathway, suggesting that SIRT1 (show SIRT1 Antibodies) gene may play a protective role against osteoarthritis.

  2. SREBP-2 is critical for survival and limb patterning during development

  3. Identify a novel signaling pathway in hepatocytes triggered by ligand-activated p75NTR (show NGFR Antibodies) that via p38 MAPK (show MAPK14 Antibodies) and caspase-3 (show CASP3 Antibodies) mediate the activation of SREBP2. This pathway may regulate LDLRs and lipid uptake particularly after injury or during tissue inflammation accompanied by an increased production of growth factors, including NGF (show NGFB Antibodies) and pro-NGF (show NGFB Antibodies).

  4. This study reveals SHP (show LAMC1 Antibodies) as a global transcriptional partner of SREBP-2 in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (show FGF19 Antibodies).

  5. activation of the sterol regulatory element binding protein-2 (SREBP2) was found to be downstream of ER stress, and this activation was affirmed to account for the intracellular accumulation of cholesterol using RNAi technique

  6. ITCH modulates SIRT6 (show SIRT6 Antibodies) and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE (show APOE Antibodies) null mice

  7. SREBP2-induced miR (show MLXIP Antibodies)-92a targets key molecules in endothelial homeostasis, including sirtuin 1 (show SIRT1 Antibodies), Kruppel-like factor 2, and Kruppel-like factor 4 (show KLF4 Antibodies), leading to NOD-like receptor family pyrin domain-containing 3 inflammasome activation and endothelial nitric oxide synthase (show NOS3 Antibodies) inhibition.

  8. The cholesterol-lowering effects of FGF21 (show FGF21 Antibodies) are abrogated by hepatic expression of sterol regulatory element-binding protein-2.

  9. Data indicate that Leishmania exploits macrophage cholesterol-dependent sterol regulatory element binding factor 2 (SREBP2) circuit to facilitate its entry and survival within the host.

  10. Demonstrate that the activation of FXR (show NR1H4 Antibodies) uncouples the expression of nuclear SREBP-2 and miR (show MLXIP Antibodies)-33, and the regulation of their respective target genes.

Human Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. mechanistic investigation provides clinical insights into protective roles of the epithelial cholesterol deficiency against excessive inflammatory responses via the SREBP2-HuR (show ELAVL1 Antibodies) circuit, although the deficiency triggers transient pro-inflammatory signals.

  2. Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells.

  3. Identify a novel signaling pathway in hepatocytes triggered by ligand-activated p75NTR (show NGFR Antibodies) that via p38 MAPK (show MAPK14 Antibodies) and caspase-3 (show CASP3 Antibodies) mediate the activation of SREBP2. This pathway may regulate LDLRs and lipid uptake particularly after injury or during tissue inflammation accompanied by an increased production of growth factors, including NGF (show NGFB Antibodies) and pro-NGF (show NGFB Antibodies).

  4. Data show that mutant p53 protein (show TP53 Antibodies) activates the sterol regulatory element-binding proteins SREBP-1 (show SREBF1 Antibodies) and SREBP-2-mediated signaling pathways in prostate cancer (PCa (show FLVCR1 Antibodies)) cells.

  5. The connections of EGFR (show EGFR Antibodies) and ERBB4 (show ERBB4 Antibodies) signaling with SREBP-2-regulated cholesterol metabolism are likely to be important in ERBB (show EGFR Antibodies)-regulated developmental processes and may contribute to metabolic remodeling in ERBB (show EGFR Antibodies)-driven cancers.

  6. Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies) activated both SREBP-1 (show SREBF1 Antibodies) and SREBP-2, whereas Akt3 (show AKT3 Antibodies) upregulated SREBP-1 (show SREBF1 Antibodies) to enhance hepatitis C virus translation.

  7. knockdown of endogenous SREBP2 in HepG2 cells lowered ACSL1 (show Acsl1 Antibodies) mRNA and protein levels.

  8. Data suggest that Hepacivirus (HCV) activates hepatocyte NLRP3 (show NLRP3 Antibodies) inflammasomes, induces lipogenic enzymes/lipid droplet formation, and up-regulates transport of SREBF1 (show SREBF1 Antibodies)/SREBF2/SCAP (show SH2D2A Antibodies) from ER to Golgi where SREBPs undergo proteolytic activation by S1P (show MBTPS1 Antibodies)/S2P (show MBTPS2 Antibodies).

  9. Data suggest lysophosphatidylcholine (LPC (show PCSK7 Antibodies)) up-regulates SREBP-2 and cholesterol efflux in vascular endothelium; 25-hydroxycholesterol (25-HC) inhibits these effects of LPC (show PCSK7 Antibodies); both LPC (show PCSK7 Antibodies) and 25-HC up-regulate release of interleukin-6 (show IL6 Antibodies) and interleukin-8 (show IL8 Antibodies).

  10. the results of the present study showed that luteolin modulates HMGCR (show HMGCR Antibodies) transcription by decreasing the expression and nuclear translocation of SREBP-2.

Pig (Porcine) Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) interaction partners

  1. dysregulation of SIRT1 (show SIRT1 Antibodies)-AMPK (show PRKAA1 Antibodies)-SREBP and stimulation of NLRP3 (show NLRP3 Antibodies) inflammasome may contribute to vascular lipid deposition and inflammation in atherosclerosis

  2. KLF13 (show KLF13 Antibodies) and SREBP-Sp1 (show SP1 Antibodies) activation interact to regulate low density lipoprotein receptor (show LDLR Antibodies) promoter function

Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2) Antigen Profile

Antigen Summary

This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.

Alternative names and synonyms associated with Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2)

  • sterol regulatory element binding transcription factor 2 (SREBF2) antibody
  • sterol regulatory element binding transcription factor 2 (srebf2) antibody
  • sterol regulatory element binding protein 2 (SREBP2) antibody
  • sterol regulatory element binding factor 2 (Srebf2) antibody
  • sterol regulatory element binding protein-2 (SREBP-2) antibody
  • sterol regulatory element binding transcription factor 2 (Srebf2) antibody
  • AI608257 antibody
  • bHLHd2 antibody
  • lop13 antibody
  • nuc antibody
  • SREBF2 antibody
  • Srebf2_retired antibody
  • SREBP-2 antibody
  • SREBP2 antibody
  • SREBP2gc antibody
  • zgc:158371 antibody

Protein level used designations for SREBF2

sterol regulatory element binding transcription factor 2 , sterol regulatory element-binding protein 2-like , sterol regulatory element binding protein 2 , SREBP-2 , sterol regulatory element-binding protein 2 , sterol regulatory element-binding transcription factor 2 , class D basic helix-loop-helix protein 2 , sterol regulatory element binding factor 2

GENE ID SPECIES
712307 Macaca mulatta
100070704 Equus caballus
100144677 Xenopus (Silurana) tropicalis
100480211 Ailuropoda melanoleuca
100552463 Anolis carolinensis
100124292 Monodelphis domestica
507102 Bos taurus
100037309 Danio rerio
100502557 Salmo salar
20788 Mus musculus
100008783 Oryctolagus cuniculus
443980 Xenopus laevis
395304 Gallus gallus
6721 Homo sapiens
481228 Canis lupus familiaris
396675 Sus scrofa
300095 Rattus norvegicus
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