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Sequences at the 9p21.3 risk locus disrupt TEAD factor binding and TEAD3-dependent TGF-beta induction of p16 in HAoSMCs. TEAD3 overexpression induced p16 in HAoSMCs homozygous for the nonrisk coronary disease allele, but not for the risk allele.
TAZ (show TAZ Proteins) negatively regulate transcription of DeltaNp63 through TEAD1,2,3 and 4 transcription factors.
Data indicate that knockdown of TEAD1 (show TEAD1 Proteins)/3/4 induces an almost identical cellular senescent phenotype as YAP (show YAP1 Proteins) silencing.
Transcription enhancer factor-5 and the GATA-like protein act in a coordinate manner to determine the placental-specific expression of the human 3beta-hydroxysteroid dehydrogenase/isomerase I enzyme
The paper described that the translation initiation codon for the TEF-5 protein was a non-AUG (AUA) codon.
The paper described that the translation initiation codon for the TEF-5 protein was a non-AUG (ATA) codon.
Experimental evidence for non-AUG translation initiation of human TEF-5. This non-AUG start site, AUA, is conserved in mouse.
DTEF-1 is a target for alpha(1)-adrenergic activation of the skeletal muscle alpha-actin (show ACTA2 Proteins) gene in cardiac myocytes
vgl (show HDLBP Proteins)-2b is expressed transiently in nascent notochord and in muscle fibres during somitogenesis.(vgl (show HDLBP Proteins)-2b) Muscle cells also express a TEAD-3 homologue, a possible partner of Vgl (show HDLBP Proteins)-2b, during myoblast differentiation and early fibre assembly.
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon.
TEA domain family member 3
, cardiac-enriched TEA domain transcription factor 1
, transcriptional enhancer factor TEF-5
, TEA domain family member 5
, transcriptional enhancer factor 5
, transcriptional enhancer factor TEF-5 (DTEF-1)
, ETF-related factor 1