Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human WWTR1 Antibodies:
anti-Mouse (Murine) WWTR1 Antibodies:
anti-Rat (Rattus) WWTR1 Antibodies:
Go to our pre-filtered search.
Human Polyclonal WWTR1 Primary Antibody for WB - ABIN153163
Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. in Cancer research 2008
Show all 8 Pubmed References
Human Polyclonal WWTR1 Primary Antibody for ChIP, ICC - ABIN258561
Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. in Biology of reproduction 2010
Show all 6 Pubmed References
Human Polyclonal WWTR1 Primary Antibody for ICC, IF - ABIN4357944
Bhat, Salazar, Balasubramaniyan, Wani, Heathcock, Hollingsworth, James, Gumin, Diefes, Kim, Turski, Azodi, Yang, Doucette, Colman, Sulman, Lang, Rao, Copray, Vaillant, Aldape: The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. in Genes & development 2011
Show all 3 Pubmed References
Human Polyclonal WWTR1 Primary Antibody for ICC, IF - ABIN4357945
Pathak, Meng, Zhang, Gnosa, Nandy, Adell, Holmlund, Sun: Tafazzin protein expression is associated with tumorigenesis and radiation response in rectal cancer: a study of Swedish clinical trial on preoperative radiotherapy. in PLoS ONE 2014
Yap (show YAP1 Antibodies)/Taz (show TAZ Antibodies)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.
Taz (show TAZ Antibodies) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.
Taz (show TAZ Antibodies)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles
When transcriptional coactivators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.
TAZ (show TAZ Antibodies) has a critical role in osteoblast differentiation in vivo
adult human and mouse hearts had more Taz (show TAZ Antibodies) than Yap1 (show YAP1 Antibodies) by mRNA and protein expression and their increases in diseased hearts were proportional and did not change Yap1 (show YAP1 Antibodies)/Taz (show TAZ Antibodies) ratio. Yap1 (show YAP1 Antibodies), Taz (show TAZ Antibodies), and Tead1 (show TEAD1 Antibodies) were accumulated in the nuclear fraction and cardiomyocyte nuclei of diseased hearts
CytoD modified MKL1, a coactivator of serum response factor (SRF) regulating CTGF induction, and promoted its nuclear localization.
WIP (show WIPF1 Antibodies) controls tumor growth by boosting signals that stabilize the YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) complex via a mechanism mediated by the endocytic/endosomal system.
TAZ (show TAZ Antibodies) is a critical factor for SRC kinase (show CSK Antibodies)-mediated intestinal tumor formation and regeneration.
YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) plays multifaceted roles for endothelial cell behaviors, proliferation, junction assembly, and metabolism in sprouting angiogenesis and barrier formation
Activation of GPR81 (show GPR81 Antibodies) decreases intracellular cAMP levels and inhibits PKA activity, leading to activation of TAZ (show TAZ Antibodies) and upregulation of PD-L1 (show CD274 Antibodies). This study reveals a critical role for lactate in the immune checkpoint pathway and an unexpected function of TAZ (show TAZ Antibodies) in tumor evasion of the T-cell-mediated immune response.
results provide evidence that TAZ (show TAZ Antibodies) and miR (show MLXIP Antibodies)-135b engage in a positive feedback loop to regulate epithelial-mesenchymal transition and metastasis in osteosarcoma, and suggest that both factors can be therapeutic targets for osteosarcoma treatment.
extracellular matrix stiffening sustains vascular cell growth and migration through YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies)-dependent glutaminolysis and anaplerosis
a stiffness-dependent YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies)-mediated positive feedback loop that drives remodeling phenotypes in pulmonary artery smooth muscle cells via reduced COX-2 (show COX2 Antibodies) and prostaglandin activity.
ETAR (show EDNRA Antibodies) stimulation acted via downstream G-protein Galphaq (show GNAQ Antibodies)/11 and Rho GTPase (show RACGAP1 Antibodies) to suppress the Hippo pathway, thus leading to YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activation, which was required for ETAR (show EDNRA Antibodies)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) axis in ETAR (show EDNRA Antibodies) signaling
Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) leads to impaired epicardial epithelial-to-mesenchymal transition (EMT (show ITK Antibodies)) and a reduction in epicardial cell proliferation and differentiation into coronary endothelial cells.
This study identifies YAP/TAZ as central mediators of VEGF signaling
TAZ (show TAZ Antibodies) is required for TGFbeta (show TGFB1 Antibodies) induction of smooth muscle genes and is also required for the differentiated VSMC phenotype; synergy between TAZ (show TAZ Antibodies) and SRF, and TAZ (show TAZ Antibodies) and Myocardin (show MYOCD Antibodies) (MyoC856), in regulating smooth muscle gene activation was observed in primary aortic vascular smooth muscle cells.
Results demonstrate a pivotal role for TAZ (show TAZ Antibodies) in regulating the differentiation of Treg cells and TH17 cells.
ABL (show ABL1 Antibodies) potentiated the assembly and activation of the RUNX2 (show RUNX2 Antibodies)-TAZ (show TAZ Antibodies) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (show PPARG Antibodies)-mediated adipogenesis.
the transcription regulators YAP (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.
These results suggest that vinculin (show VCL Antibodies) promotes the nuclear localization of transcription factor TAZ (show TAZ Antibodies) to inhibit the adipocyte differentiation on rigid extracellular matrix.
TAZ (show TAZ Antibodies) represents a previously unrecognized factor that contributes to the critical process of steatosis-to-Nonalcoholic Steatohepatitis progression.
This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.
WW domain containing transcription regulator 1
, WW domain-containing transcription regulator protein 1
, WW domain-containing transcription regulator protein 1-like
, transcriptional co-activator with PDZ-binding motif
, transcriptional coactivator with PDZ-binding motif
, transcriptional coactivator with PDZ binding motif
, transcriptional co-activator with PDZ-binding motif (TA)Z
, transcriptional co-activator with PDZ-binding motif (TAZ)