Browse our anti-WWTR1 (WWTR1) Antibodies

Full name:
anti-WW Domain Containing Transcription Regulator 1 Antibodies (WWTR1)
On www.antibodies-online.com are 53 WW Domain Containing Transcription Regulator 1 (WWTR1) Antibodies from 14 different suppliers available. Additionally we are shipping WWTR1 Proteins (5) and WWTR1 Kits (2) and many more products for this protein. A total of 64 WWTR1 products are currently listed.
Synonyms:
2310058J06Rik, 2610021I22Rik, C78399, Taz, WWTR1
list all antibodies Gene Name GeneID UniProt
WWTR1 25937 Q9GZV5
WWTR1 97064 Q9EPK5
WWTR1 295062  

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anti-Human WWTR1 Antibodies:

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Top referenced anti-WWTR1 Antibodies

  1. Human Polyclonal WWTR1 Primary Antibody for WB - ABIN153163 : Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. in Cancer research 2008 (PubMed)
    Show all 8 references for 153163

  2. Human Polyclonal WWTR1 Primary Antibody for ChIP, ICC - ABIN258561 : Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. in Biology of reproduction 2010 (PubMed)
    Show all 6 references for 258561

  3. Human Polyclonal WWTR1 Primary Antibody for EIA, WB - ABIN955592 : Remue, Meerschaert, Oka, Boucherie, Vandekerckhove, Sudol, Gettemans: TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. in FEBS letters 2010 (PubMed)
    Show all 5 references for 955592

  4. Human Polyclonal WWTR1 Primary Antibody for ICC, IF - ABIN4357944 : Bhat, Salazar, Balasubramaniyan, Wani, Heathcock, Hollingsworth, James, Gumin, Diefes, Kim, Turski, Azodi, Yang, Doucette, Colman, Sulman, Lang, Rao, Copray, Vaillant, Aldape: The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. in Genes & development 2011 (PubMed)
    Show all 3 references for 4357944

  5. Cow (Bovine) Polyclonal WWTR1 Primary Antibody for WB - ABIN2779708 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. in Science (New York, N.Y.) 2005 (PubMed)

More Antibodies against WWTR1 Interaction Partners

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (show YAP1 Antibodies)/Taz (show TAZ Antibodies)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (show TAZ Antibodies) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (show TAZ Antibodies)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (show TAZ Antibodies) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. results provide evidence that TAZ (show TAZ Antibodies) and miR (show MLXIP Antibodies)-135b engage in a positive feedback loop to regulate epithelial-mesenchymal transition and metastasis in osteosarcoma, and suggest that both factors can be therapeutic targets for osteosarcoma treatment.

  2. extracellular matrix stiffening sustains vascular cell growth and migration through YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies)-dependent glutaminolysis and anaplerosis

  3. a stiffness-dependent YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies)-mediated positive feedback loop that drives remodeling phenotypes in pulmonary artery smooth muscle cells via reduced COX-2 (show COX2 Antibodies) and prostaglandin activity.

  4. ETAR (show EDNRA Antibodies) stimulation acted via downstream G-protein Galphaq (show GNAQ Antibodies)/11 and Rho GTPase (show RACGAP1 Antibodies) to suppress the Hippo pathway, thus leading to YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activation, which was required for ETAR (show EDNRA Antibodies)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) axis in ETAR (show EDNRA Antibodies) signaling

  5. Various studies show that in human cancers, the Hippo pathway is frequently deregulated allowing YAP1 (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) to escape the inhibition by the Hippo pathway. The upregulation of YAP1 (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) induces epithelial-mesenchymal transition and increases drug resistance in cancer cells. TAZ (show TAZ Antibodies) is implicated in cancer stemness.[review]

  6. Results demonstrate a pivotal role for TAZ (show TAZ Antibodies) in regulating the differentiation of Treg cells and TH17 cells.

  7. the transcription regulators YAP (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  8. In colorectal carcinoma TIAM1 (show TIAM1 Antibodies) suppresses tumor progression by regulating YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activity.

  9. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP (show YAP1 Antibodies) and TAZ (show TAZ Antibodies), promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. [review]

  10. SGK1 (show SGK1 Antibodies) promotes YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) transcriptional activity. SGK1 (show SGK1 Antibodies) enhances YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) activity by upregulating YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies). SGK1 (show SGK1 Antibodies) is a transcriptional target of YAP (show YAP1 Antibodies). SGK1 (show SGK1 Antibodies) stabilizes TAZ (show TAZ Antibodies) by inhibiting GSK3beta (show GSK3b Antibodies).

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) leads to impaired epicardial epithelial-to-mesenchymal transition (EMT (show ITK Antibodies)) and a reduction in epicardial cell proliferation and differentiation into coronary endothelial cells.

  2. This study identifies YAP/TAZ as central mediators of VEGF signaling

  3. TAZ (show TAZ Antibodies) is required for TGFbeta (show TGFB1 Antibodies) induction of smooth muscle genes and is also required for the differentiated VSMC phenotype; synergy between TAZ (show TAZ Antibodies) and SRF, and TAZ (show TAZ Antibodies) and Myocardin (show MYOCD Antibodies) (MyoC856), in regulating smooth muscle gene activation was observed in primary aortic vascular smooth muscle cells.

  4. Results demonstrate a pivotal role for TAZ (show TAZ Antibodies) in regulating the differentiation of Treg cells and TH17 cells.

  5. ABL (show ABL1 Antibodies) potentiated the assembly and activation of the RUNX2 (show RUNX2 Antibodies)-TAZ (show TAZ Antibodies) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (show PPARG Antibodies)-mediated adipogenesis.

  6. the transcription regulators YAP (show YAP1 Antibodies) and TAZ (show TAZ Antibodies) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  7. These results suggest that vinculin (show VCL Antibodies) promotes the nuclear localization of transcription factor TAZ (show TAZ Antibodies) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  8. TAZ (show TAZ Antibodies) represents a previously unrecognized factor that contributes to the critical process of steatosis-to-Nonalcoholic Steatohepatitis progression.

  9. both Snail (show SNAI1 Antibodies) and Slug (show SNAI2 Antibodies) are able to form binary complexes with either YAP (show YAP1 Antibodies) or TAZ (show TAZ Antibodies) that, together, control YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) transcriptional activity and function throughout mouse development.

  10. results demonstrate that skeletal stem/stromal cell mobilize Snail (show SNAI1 Antibodies)/Slug (show SNAI2 Antibodies)-YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) complexes to control stem cell function

WWTR1 Antigen Profile

Antigen Summary

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) antibody
  • WW domain containing transcription regulator 1 (WWTR1) antibody
  • WW domain containing transcription regulator 1 (Wwtr1) antibody
  • 2310058J06Rik antibody
  • 2610021I22Rik antibody
  • C78399 antibody
  • Taz antibody
  • WWTR1 antibody

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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