Browse our WWTR1 (WWTR1) ELISA Kits

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WW Domain Containing Transcription Regulator 1 ELISA Kits (WWTR1)
On www.antibodies-online.com are 3 WW Domain Containing Transcription Regulator 1 (WWTR1) ELISA Kits from 3 different suppliers available. Additionally we are shipping WWTR1 Antibodies (53) and WWTR1 Proteins (5) and many more products for this protein. A total of 65 WWTR1 products are currently listed.
Synonyms:
2310058J06Rik, 2610021I22Rik, C78399, Taz, WWTR1
list all ELISA KIts Gene Name GeneID UniProt
WWTR1 25937 Q9GZV5
Mouse WWTR1 WWTR1 97064 Q9EPK5
Rat WWTR1 WWTR1 295062  

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WWTR1 (WWTR1) ELISA Kits by Reactivity

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More ELISA Kits for WWTR1 Interaction Partners

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (show YAP1 ELISA Kits)/Taz (show TAZ ELISA Kits)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (show TAZ ELISA Kits) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (show TAZ ELISA Kits)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (show YAP1 ELISA Kits) and Taz (show TAZ ELISA Kits) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (show TAZ ELISA Kits) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. ETAR (show EDNRA ELISA Kits) stimulation acted via downstream G-protein Galphaq (show GNAQ ELISA Kits)/11 and Rho GTPase (show RACGAP1 ELISA Kits) to suppress the Hippo pathway, thus leading to YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) activation, which was required for ETAR (show EDNRA ELISA Kits)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) axis in ETAR (show EDNRA ELISA Kits) signaling

  2. Various studies show that in human cancers, the Hippo pathway is frequently deregulated allowing YAP1 (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) to escape the inhibition by the Hippo pathway. The upregulation of YAP1 (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) induces epithelial-mesenchymal transition and increases drug resistance in cancer cells. TAZ (show TAZ ELISA Kits) is implicated in cancer stemness.[review]

  3. Results demonstrate a pivotal role for TAZ (show TAZ ELISA Kits) in regulating the differentiation of Treg cells and TH17 cells.

  4. the transcription regulators YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  5. In colorectal carcinoma TIAM1 suppresses tumor progression by regulating YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) activity.

  6. Growing evidence suggests that transcriptional effectors of the Hippo pathway, YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits), promote resistance to various anti-cancer therapies, including cytotoxic chemotherapy, molecular targeted therapy, and radiation therapy. [review]

  7. SGK1 (show SGK1 ELISA Kits) promotes YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) transcriptional activity. SGK1 (show SGK1 ELISA Kits) enhances YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) activity by upregulating YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits). SGK1 (show SGK1 ELISA Kits) is a transcriptional target of YAP (show YAP1 ELISA Kits). SGK1 (show SGK1 ELISA Kits) stabilizes TAZ (show TAZ ELISA Kits) by inhibiting GSK3beta (show GSK3b ELISA Kits).

  8. YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits), which are inhibited by the HIPPO tumor suppressor pathway, modify PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) pathway signaling in endometrial cancer.

  9. These results suggest that vinculin (show VCL ELISA Kits) promotes the nuclear localization of transcription factor TAZ (show TAZ ELISA Kits) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  10. TAZ (show TAZ ELISA Kits) regulates cell proliferation and sensitivity to vitamin D3 in intrahepatic cholangiocarcinoma by regulating tp53 (show TP53 ELISA Kits)/CYP24A1 (show CYP24A1 ELISA Kits) pathway.

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Results demonstrate a pivotal role for TAZ (show TAZ ELISA Kits) in regulating the differentiation of Treg cells and TH17 cells.

  2. ABL (show ABL1 ELISA Kits) potentiated the assembly and activation of the RUNX2 (show RUNX2 ELISA Kits)-TAZ (show TAZ ELISA Kits) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (show PPARG ELISA Kits)-mediated adipogenesis.

  3. the transcription regulators YAP (show YAP1 ELISA Kits) and TAZ (show TAZ ELISA Kits) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  4. These results suggest that vinculin (show VCL ELISA Kits) promotes the nuclear localization of transcription factor TAZ (show TAZ ELISA Kits) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  5. TAZ (show TAZ ELISA Kits) represents a previously unrecognized factor that contributes to the critical process of steatosis-to-Nonalcoholic Steatohepatitis progression.

  6. both Snail (show SNAI1 ELISA Kits) and Slug (show SNAI2 ELISA Kits) are able to form binary complexes with either YAP (show YAP1 ELISA Kits) or TAZ (show TAZ ELISA Kits) that, together, control YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) transcriptional activity and function throughout mouse development.

  7. results demonstrate that skeletal stem/stromal cell mobilize Snail (show SNAI1 ELISA Kits)/Slug (show SNAI2 ELISA Kits)-YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits) complexes to control stem cell function

  8. Results found that sclerostin (show SOST ELISA Kits) enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (show TAZ ELISA Kits)-responsive transcriptional activity and TAZ (show TAZ ELISA Kits)-responsive gene expression, indicating a role for TAZ (show TAZ ELISA Kits) as a regulator of adipogenesis by sclerostin (show SOST ELISA Kits).

  9. Expression of TAZ (show TAZ ELISA Kits) promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

  10. Tead2 transcription factors are crucial regulators of the cellular distribution of Yap (show YAP1 ELISA Kits) and Taz (show TAZ ELISA Kits), and together they control the expression of genes critical for EMT (show ITK ELISA Kits) and metastasis.

WWTR1 Antigen Profile

Antigen Summary

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) Elisa Kit
  • WW domain containing transcription regulator 1 (WWTR1) Elisa Kit
  • WW domain containing transcription regulator 1 (Wwtr1) Elisa Kit
  • 2310058J06Rik Elisa Kit
  • 2610021I22Rik Elisa Kit
  • C78399 Elisa Kit
  • Taz Elisa Kit
  • WWTR1 Elisa Kit

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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