Browse our anti-HDAC4 (HDAC4) Antibodies

Full name:
anti-Histone Deacetylase 4 Antibodies (HDAC4)
On are 328 Histone Deacetylase 4 (HDAC4) Antibodies from 37 different suppliers available. Additionally we are shipping HDAC4 Kits (17) and HDAC4 Proteins (16) and many more products for this protein. A total of 381 HDAC4 products are currently listed.
4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701
list all antibodies Gene Name GeneID UniProt
HDAC4 9759 P56524
HDAC4 208727 Q6NZM9
HDAC4 363287 Q99P99

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anti-Human HDAC4 Antibodies:

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Top referenced anti-HDAC4 Antibodies

  1. Human Polyclonal HDAC4 Primary Antibody for ICC, IF - ABIN269450 : Geng, Cuneo, Fu, Tu, Atadja, Hallahan: Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer. in Cancer research 2006 (PubMed)
    Show all 5 references for 269450

  2. Human Polyclonal HDAC4 Primary Antibody for EIA, WB - ABIN493047 : Bolden, Peart, Johnstone: Anticancer activities of histone deacetylase inhibitors. in Nature reviews. Drug discovery 2006 (PubMed)
    Show all 5 references for 493047

  3. Human Polyclonal HDAC4 Primary Antibody for EIA, WB - ABIN356644 : Chan, Sun, Yang, Zhu, Wu: Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for 356644

  4. Human Polyclonal HDAC4 Primary Antibody for WB - ABIN196930 : Wang, Kruhlak, Wu, Bertos, Vezmar, Posner, Bazett-Jones, Yang: Regulation of histone deacetylase 4 by binding of 14-3-3 proteins. in Molecular and cellular biology 2000 (PubMed)
    Show all 2 references for 196930

  5. Human Polyclonal HDAC4 Primary Antibody for IF, WB - ABIN197338 : Grozinger, Schreiber: Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 2 references for 197338

  6. Human Polyclonal HDAC4 Primary Antibody for WB - ABIN387951 : Kao, McKenna, Guenther, Muschel, Lazar, Yen: Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. in The Journal of cell biology 2003 (PubMed)
    Show all 2 references for 387951

  7. Cow (Bovine) Polyclonal HDAC4 Primary Antibody for WB - ABIN2778341 : Lee, Lin, Luo, Lee, Lee, Aird, Hwang, Yang et al.: Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and ... in Molecular pharmacology 2008 (PubMed)

  8. Human Polyclonal HDAC4 Primary Antibody for IHC, WB - ABIN223298 : Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity. in The Journal of biological chemistry 2013 (PubMed)

More Antibodies against HDAC4 Interaction Partners

Fruit Fly (Drosophila melanogaster) Histone Deacetylase 4 (HDAC4) interaction partners

  1. We also demonstrate that HDAC4 and Ubc9 (show UBE2I Antibodies) interact genetically during memory formation, opening new avenues for investigating the mechanisms through which HDAC4 regulates memory formation and other neurological processes.

  2. RNAi-mediated knockdown of HDAC4 in Drosophila dampens circadian function.

  3. HDAC4 is not only a repressor of long-term memory, but also modulates normal memory formation

  4. dHDAC4, is a novel, catalytically active class II Drosophila histone deacetylase (show HDAC1 Antibodies) and is involved in the segmentation regulatory pathway and suggested complex transcriptional regulation as a potential mechanism that controls its expression

Human Histone Deacetylase 4 (HDAC4) interaction partners

  1. TGF-beta1 (show TGFB1 Antibodies) increases NADPH oxidase 4 (NOX4 (show NOX4 Antibodies)) mRNA and protein expression in normal human lung fibroblasts (NHLFs) and causes nuclear export of HDAC4.

  2. elevated HO-1 (show HMOX1 Antibodies) produced less reactive oxygen species, resulting in nuclear localization of HDAC4 and miR (show MLXIP Antibodies)-206 repression.

  3. Results show that HDAC4 is a direct target of miR (show MLXIP Antibodies)-29b in multiple myeloma cells and its high mRNA expression inversely correlates with miR (show MLXIP Antibodies)-29b levels in multiple myeloma samples.

  4. in leiomyosarcomas (LMS), this two-faced trait of MEF2 (show MEF2A Antibodies) is relevant for tumor aggressiveness. Class IIa HDACs are overexpressed in 22% of LMS, where high levels of MEF2 (show MEF2A Antibodies), HDAC4 and HDAC9 (show HDAC9 Antibodies) inversely correlate with overall survival. The knock out of HDAC9 (show HDAC9 Antibodies) suppresses the transformed phenotype of LMS cells, by restoring the transcriptional proficiency of some MEF2 (show MEF2A Antibodies)-target loci

  5. Collectively, we suggest that VSV treatment will be a useful therapeutic strategy for HCV-infected hepatocellular carcinoma cells because HCV core protein suppresses the anti-viral threshold by down-regulation of the STAT1 (show STAT1 Antibodies)-HDAC4 signaling axis.

  6. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13 (show MMP13 Antibodies), ADAMTS-5 (show ADAMTS5 Antibodies), and HDAC-4, and modulates the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway activation.

  7. HDAC4 is a target gene of miR (show MLXIP Antibodies)-140 and is involved in miR (show MLXIP Antibodies)-140-mediated suppression of osteosarcoma cells.

  8. HDAC4 increases endogenous SIRT1 (show SIRT1 Antibodies) expression by enhancing its sumoylation modification levels

  9. we demonstrate that nuclear HDAC4 is a key regulator promoting the progressive epithelial ovarian cancer on fibrillar collagen matrices

  10. HDAC4 destabilizes MAP1S (show MAP1S Antibodies), suppresses autophagy flux and promotes the accumulation of mHTT aggregates.

Mouse (Murine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. Nuclear HDAC4 (show HDAC5 Antibodies) binds to chromatin as well as to MEF2A (show MEF2A Antibodies) transcription factor, leading to histone deacetylation and altered neuronal gene expression. By using a Cdkl5 (show CDKL5 Antibodies) knockout (Cdkl5 (show CDKL5 Antibodies) -/Y) mouse model, we found that hypophosphorylated HDAC4 (show HDAC5 Antibodies) translocates to the nucleus of neural precursor cells, thereby reducing histone 3 acetylation.

  2. Data (including data from studies using knockout mice) suggest that S100A1 (show S100A1 Antibodies) (S-100 calcium-binding protein (show GUCA1B Antibodies) A1 (show BCL2A1 Antibodies), alpha chain (show FCGRT Antibodies)) is involved in protein kinase A- (RIIalpha and RIIbeta (show PRKAR2B Antibodies))-dependent signaling resulting in nuclear redistribution/influx of HDAC4 (histone deacetylase 4 (show HDAC5 Antibodies)) in skeletal muscle fibers.

  3. results are the first to demonstrate that the protective effects of irisin (show FNDC5 Antibodies) in cardiomyoblasts exposed to hypoxia/reoxygenation might be associated with HDAC4 (show HDAC5 Antibodies) degradation.

  4. PC3/Tis21 (show BTG2 Antibodies) associates with HDAC1 (show HDAC1 Antibodies), HDAC4 (show HDAC5 Antibodies), and HDAC9 (show HDAC9 Antibodies) in vivo, in fibroblast cells.

  5. HDAC4 (show HDAC5 Antibodies) increases endogenous SIRT1 (show SIRT1 Antibodies) expression by enhancing its sumoylation modification levels

  6. postmitotic expression SOD1G93A mutant gene promotes a FAPS phenotype in C2C12 cells, by upregulating HDAC4 (show HDAC5 Antibodies) protein and preventing the BAF60C (show SMARCD3 Antibodies)-SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complex myogenic commitment

  7. miR (show MLXIP Antibodies)-29a was involved in the regulation of HDAC4 (show HDAC5 Antibodies) and modulation of the profibrogenic phenotype in hepatic stellate cells.

  8. This study demonstrated that hdac4 (show HDAC5 Antibodies) increase in skeletal muscle in muscle atrophy.

  9. These results demonstrate that miR (show MLXIP Antibodies)-140 ensures the robustness of the PTHrP (show PTHLH Antibodies)/HDAC4 (show HDAC5 Antibodies) regulatory system by suppressing MEF2C (show MEF2C Antibodies)-inducing stimuli.

  10. The data of this study demonstrated pronounced and distinctively different changes in the expression of class IV HDAC (show HDAC3 Antibodies) in subfields of the hippocampus after an acute status epilepticus, during epileptogenesis and in chronic TLE.

Zebrafish Histone Deacetylase 4 (HDAC4) interaction partners

  1. Results demonstrate that Hdac4 is a regulator of cranial neural crest-derived palatal skeletal precursors during early embryogenesis.

Cow (Bovine) Histone Deacetylase 4 (HDAC4) interaction partners

  1. our results revealed the mechanism in which miR-1 and miR (show MYLIP Antibodies)-206 positively regulate bovine skeletal muscle satellite cell myogenic differentiation via Pax7 (show PAX7 Antibodies) and HDAC4 downregulation.

HDAC4 Antigen Profile

Antigen Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Alternative names and synonyms associated with HDAC4

  • histone deacetylase 4 (PTRG_03699) antibody
  • histone deacetylase 4 (PGTG_15512) antibody
  • CG1770 gene product from transcript CG1770-RG (HDAC4) antibody
  • DanaGF18710-PA (DanaHDAC4) antibody
  • histone deacetylase 4 (HDAC4) antibody
  • histone deacetylase 4 (Hdac4) antibody
  • histone deacetylase 4 (hdac4) antibody
  • 4932408F19Rik antibody
  • AHO3 antibody
  • AI047285 antibody
  • BDMR antibody
  • CG1770 antibody
  • DanaGF18710 antibody
  • dana_GLEANR_19966 antibody
  • dHDAC4 antibody
  • Dmel\\CG1770 antibody
  • dmHDA405 antibody
  • GC1770 antibody
  • GF18710 antibody
  • HA6116 antibody
  • HD4 antibody
  • HDAC antibody
  • HDAC-4 antibody
  • HDAC-A antibody
  • HDAC4 antibody
  • HDAC4a antibody
  • HDACA antibody
  • wu:fa96d08 antibody
  • wu:fc56f08 antibody
  • zgc:152701 antibody

Protein level used designations for HDAC4

histone deacetylase 4 , CG1770-PB , CG1770-PD , CG1770-PE , CG1770-PF , CG1770-PG , CG1770-PH , CG1770-PI , CG1770-PJ , HDAC4-PB , HDAC4-PD , HDAC4-PE , HDAC4-PF , HDAC4-PG , HDAC4-PH , HDAC4-PI , HDAC4-PJ , DanaGF18710-PA , DanaHDAC4-PA , GF18710-PA , HDAC4 , HDAC4-PA , histone deacetylase A , HD4

6341931 Pyrenophora tritici-repentis Pt-1C-BFP
10547054 Puccinia graminis f. sp. tritici CRL 75-36-700-3
32278 Drosophila melanogaster
6507946 Drosophila ananassae
9759 Homo sapiens
208727 Mus musculus
363287 Rattus norvegicus
374207 Gallus gallus
568877 Danio rerio
607662 Canis lupus familiaris
517559 Bos taurus
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