Browse our anti-N-Cadherin (CDH2) Antibodies

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anti-Cadherin 2 Antibodies (CDH2)
On are 394 Cadherin 2 (CDH2) Antibodies from 33 different suppliers available. Additionally we are shipping N-Cadherin Kits (41) and N-Cadherin Proteins (15) and many more products for this protein. A total of 458 N-Cadherin products are currently listed.
Cadherin-2, CD325, CDH2, CDHN, CDw325, glo, lyr, N-cadherin, NCAD, pac, wu:fb47h04
list all antibodies Gene Name GeneID UniProt
CDH2 12558 P15116
Anti-Rat CDH2 CDH2 83501 Q9Z1Y3
CDH2 1000 P19022

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All available anti-N-Cadherin Antibodies

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Top referenced anti-N-Cadherin Antibodies

  1. Human Monoclonal N-Cadherin Primary Antibody for ICC, IF - ABIN4337604 : Makrigiannakis, Coukos, Christofidou-Solomidou, Gour, Radice, Blaschuk, Coutifaris: N-cadherin-mediated human granulosa cell adhesion prevents apoptosis: a role in follicular atresia and luteolysis? in The American journal of pathology 1999 (PubMed)
    Show all 21 references for 4337604

  2. Chicken Monoclonal N-Cadherin Primary Antibody for IF, IP - ABIN968249 : Cowin: Unraveling the cytoplasmic interactions of the cadherin superfamily. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 4 references for 968249

  3. Human Monoclonal N-Cadherin Primary Antibody for BI, FACS - ABIN967678 : Knudsen, Soler, Johnson, Wheelock: Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. in The Journal of cell biology 1995 (PubMed)
    Show all 3 references for 967678

  4. Chicken Monoclonal N-Cadherin Primary Antibody for IHC (fro), WB - ABIN1105630 : Walsh, Barton, Putt, Moore, Kelsell, Spurr, Goodfellow: N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene. in Journal of neurochemistry 1990 (PubMed)
    Show all 3 references for 1105630

  5. Human Monoclonal N-Cadherin Primary Antibody for ICC, FACS - ABIN969038 : Sharma, Henderson: IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli. in The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for 969038

  6. Human Polyclonal N-Cadherin Primary Antibody for IF (p), IHC (p) - ABIN738726 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Show all 2 references for 738726

  7. Human Polyclonal N-Cadherin Primary Antibody for FACS, ICC - ABIN4899286 : Windus, Kiss, Glover, Avery: In vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer. in Experimental cell research 2012 (PubMed)

  8. Human Polyclonal N-Cadherin Primary Antibody for FACS - ABIN4895858 : Tran, Choi, Wszolek, Navai, Lee, Nitti, Wen, Flores, Siefker-Radtke, Czerniak, Dinney, Barton, McConkey: The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205. in The Journal of biological chemistry 2013 (PubMed)

  9. Human Monoclonal N-Cadherin Primary Antibody for FACS, IHC - ABIN4899285 : Yuan, Chen, Ma, Cao, Liu: Reelin is involved in transforming growth factor-β1-induced cell migration in esophageal carcinoma cells. in PLoS ONE 2012 (PubMed)

More Antibodies against N-Cadherin Interaction Partners

Xenopus laevis Cadherin 2 (CDH2) interaction partners

  1. the switch from E- to N-cadherin during epithelial-mesenchymal transition is essential for acquisition of Contact inhibition of locomotion behavior.

Mouse (Murine) Cadherin 2 (CDH2) interaction partners

  1. N-cadherin-null enteric neural crest cells do not respond to C3a (show C3 Antibodies) co-attraction. C3a (show C3 Antibodies) regulates cell migration in a N-cadherin-dependent process.

  2. Study demonstrates a critical role of presynaptic cadherin/catenin/p140Cap (show SRCIN1 Antibodies) cell adhesion complexes in stabilizing functional synapses and spines in the developing neocortex.

  3. Knock-down of ZBED6 in insulin (show INS Antibodies)-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.

  4. Knockdown of N-cadherin in 3T3 fibroblasts did not impede gap closure in a soft tissue wound healing model.

  5. N-cadherin modulates Lrp6 (show LRP6 Antibodies)/PTHR1 (show PTH1R Antibodies) interaction, restraining the intensity of parathyroid hormone (show PTH Antibodies)-induced beta-catenin (show CTNNB1 Antibodies) signaling

  6. Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice.

  7. CRP (show CRP Antibodies) suppresses expression of N-cadherin (p < 0.01), a mesenchymal marker of EMT (show ITK Antibodies), and ZEB-1 (show ZEB1 Antibodies), an EMT (show ITK Antibodies)-related transcription factor (p < 0.01). These findings suggest that CRP (show CRP Antibodies) inhibits EMT (show ITK Antibodies) in a MCA (show RSPH1 Antibodies)-38 tumor-bearing mouse model.

  8. these studies suggest that N-cadherin may represent a viable therapeutic target to prevent the dissemination of MM PCs and delay MM disease progression.

  9. N-cadherin is required for the establishment and maintenance of anterior heart field -cardiac progenitor cells.

  10. delta-Catenin (show CTNND2 Antibodies) Regulates Spine Architecture via Cadherin and PDZ (show INADL Antibodies)-dependent Interactions.

Zebrafish Cadherin 2 (CDH2) interaction partners

  1. Newly synthesized N-cadherin molecules move from the lateral to the basal surface of cardiomyocytes during trabeculation. This localization requires Erbb2 (show ERBB2 Antibodies) signaling.

  2. Throughout somitogenesis, Cadherin2 promotes extracellular matrix (ECM (show MMRN1 Antibodies)) assembly along tissue boundaries and inhibits ECM (show MMRN1 Antibodies) assembly in the tissue mesenchyme.

  3. Cdon (show CDON Antibodies) is required to localize N-cadherin to the cell membrane in migratory neural crest cells for directed migration.

  4. shows that a dominant-negative nuclear localization mutant of Sox3 (show SOX3 Antibodies) can cause ectopic expression of organizer genes via a mechanism that activates all of these earlier factors, resulting in later axis duplication including major bifurcations of the CNS.

  5. Genetic suppression of N-cadherin function interferes with basal migration of retinal progenitors and subsequent regeneration of HuC (show ELAVL3 Antibodies)/D(+) inner retinal neurons.

  6. N-cadherin deficiency in Danio does not prevent the first tooth from starting to develop, but stops its development at the early cytodifferentiation stage and completely inhibits the development of the other first-generation teeth.

  7. N-cadherin regulates motor axon growth and branching without severely affecting the mechanisms that control axonal target selection.

  8. Slit-Robo signaling downregulates N-cadherin activity to allow apical retraction in newly generated retinal ganglion cells.

  9. demonstration of a novel mechanism of cell adhesion, mediated by a complex of Protocadherin-19 (Pcdh19 (show PCDH19 Antibodies)) and N-cadherin (Ncad)

  10. zebrafish N-cadherin restricts cell proliferation in the dorsal region of the neural tube by regulating cell-cycle length.

Human Cadherin 2 (CDH2) interaction partners

  1. fluorescent imaging to demonstrate Ncad-mediated single cell responses to developmental cues within hydrogels towards chondrogenesis.

  2. Our data demonstrate that N-Cadherin was markedly overexpressed and miR (show MLXIP Antibodies)-199b-5p was significantly downregulated in hepatocellular carcinoma (HCC (show FAM126A Antibodies)). MiR (show MLXIP Antibodies)-199b-5p exerts inhibitory effects on EMT (show ITK Antibodies), and directly targets N-cadherin in HCC (show FAM126A Antibodies), supporting the potential utility of miR (show MLXIP Antibodies)-199b-5p as a promising strategy to treat HCC (show FAM126A Antibodies)

  3. Study demonstrates a critical role of presynaptic cadherin/catenin/p140Cap (show SRCIN1 Antibodies) cell adhesion complexes in stabilizing functional synapses and spines in the developing neocortex.

  4. overexpression of SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies) increased E-cadherin (show CDH1 Antibodies) and decreased N-cadherin and vimentin (show VIM Antibodies) protein levels, indicating that SPRY4 (show SPRY4 Antibodies)-IT1 (show HAUS3 Antibodies) may regulate ovarian cancer cell metastasis through the inhibition of epithelial-mesenchymal transition.

  5. investigated the in vitro tumor/metastasis suppressor effects of plakoglobin in ovarian cancer cell lines with mutant p53 expression and different cadherin profiles

  6. These results uncover a new role for p120 catenin (show CTNND1 Antibodies) bound to the N-cadherin precursor ensuring its trafficking through the biosynthetic pathway towards the cell surface.

  7. Finding that the cells expressing N-cadherin gave rise to tumors with no expression of N-cadherin is in agreement with the classical view of epithelial to mesenchymal transition. Epithelial to mesenchymal transition and N-cadherin are associated with dissemination and not with the ability to establish new tumor growth.

  8. findings suggest that E-cadherin (show CDH1 Antibodies) and P-cadherin, but not N-cadherin staining, might be useful in diagnosing CIN (show PDXP Antibodies) and for predicting prognosis in patients with early-stage Cervical Squamous Cell Carcinoma.

  9. NKX6.1 (show NKX6-1 Antibodies) directly enhances the mRNA level of E-cadherin (show CDH1 Antibodies) by recruiting BAF155 (show SMARCC1 Antibodies) coactivator and represses that of vimentin (show VIM Antibodies) and N-cadherin by recruiting RBBP7 (retinoblastoma binding protein 7 (show RBBP7 Antibodies)) corepressor.

  10. Impairment of E-cadherin (show CDH1 Antibodies)/N-cadherin adhesion abrogates the ability of Cancer-associated fibroblasts to guide collective cell migration and blocks cancer cell invasion.

N-Cadherin (CDH2) Antigen Profile

Antigen Summary

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Alternative names and synonyms associated with N-Cadherin (CDH2)

  • cadherin 2, type 1, N-cadherin (neuronal) (cdh2) antibody
  • cadherin 2 (Cdh2) antibody
  • cadherin 2, neuronal (cdh2) antibody
  • cadherin 2, type 1, N-cadherin (neuronal) (CDH2) antibody
  • cadherin 2, type 1, N-cadherin (neuronal) (Cdh2) antibody
  • cadherin-2-like (LOC100411112) antibody
  • neural-cadherin-like (LOC427547) antibody
  • Cadherin-2 antibody
  • CD325 antibody
  • CDH2 antibody
  • CDHN antibody
  • CDw325 antibody
  • glo antibody
  • lyr antibody
  • N-cadherin antibody
  • NCAD antibody
  • pac antibody
  • wu:fb47h04 antibody

Protein level used designations for anti-Cadherin 2 (CDH2) Antibodies

cadherin 2, type 1, N-cadherin (neuronal) , cadherin-2 , neural cadherin , cadherin 2 type 1 N-cadherin (neuronal) , N-cadherin , Neural cadherin , glass onion , labyrinth , n-cadherin , parachute , N-cadherin 1 , cadherin 2, N-cadherin (neuronal) , calcium-dependent adhesion protein, neuronal , neural-cadherin , cadherin 2, type 1 preproprotein , cadherin-2-like

495284 Xenopus laevis
100151712 Xenopus (Silurana) tropicalis
12558 Mus musculus
83501 Rattus norvegicus
100689204 Cricetulus griseus
30291 Danio rerio
1000 Homo sapiens
414745 Gallus gallus
281062 Bos taurus
480169 Canis lupus familiaris
100286861 Sus scrofa
101082701 Felis catus
100065078 Equus caballus
100170321 Ovis aries
100328895 Oryctolagus cuniculus
100714783 Cavia porcellus
100411112 Callithrix jacchus
427547 Gallus gallus
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