Browse our anti-Regulator of Calcineurin 1 (RCAN1) Antibodies

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anti-Regulator of Calcineurin 1 Antibodies (RCAN1)
On are 171 Regulator of Calcineurin 1 (RCAN1) Antibodies from 22 different suppliers available. Additionally we are shipping Regulator of Calcineurin 1 Proteins (16) and Regulator of Calcineurin 1 Kits (7) and many more products for this protein. A total of 205 Regulator of Calcineurin 1 products are currently listed.
2410048A02Rik, AA408855, Adapt78, AI429645, AL024459, AV028423, CALP1L, CDHF1, CSP1, DG2/DG3, DSC1, Dscr1, Mcip1, MGC53636, MGC69428, rcan1, RCN1, wu:fr92c05
list all antibodies Gene Name GeneID UniProt
RCAN1 1823 Q08554
RCAN1 54720 Q9JHG6
RCAN1 266766 Q6IN33

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Top referenced anti-Regulator of Calcineurin 1 Antibodies

  1. Human Polyclonal RCAN1 Primary Antibody for WB - ABIN390298 : Hirakawa, Nary, Medh: Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis. in Journal of molecular signaling 2009 (PubMed)
    Show all 6 references for 390298

  2. Human Polyclonal RCAN1 Primary Antibody for EIA, WB - ABIN358860 : Minami, Horiuchi, Miura, Abid, Takabe, Noguchi, Kohro, Ge, Aburatani, Hamakubo, Kodama, Aird: Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for 358860

  3. Cow (Bovine) Polyclonal RCAN1 Primary Antibody for WB - ABIN2780590 : Riper, Jayakumar, Latchana, Bhoiwala, Mitchell, Valenti, Crawford: Regulation of vascular function by RCAN1 (ADAPT78). in Archives of biochemistry and biophysics 2008 (PubMed)
    Show all 2 references for 2780590

  4. Mouse (Murine) Polyclonal RCAN1 Primary Antibody for ELISA, WB - ABIN4349720 : Lee, Garvey, Baras, Lemmon, Gomez, Schoppee Bortz, Daum, LeBoeuf, Wamhoff: Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. in Human molecular genetics 2009 (PubMed)

  5. Human Polyclonal RCAN1 Primary Antibody for EIA, WB - ABIN358861 : Yang, Chen, Edgar, Li, Molkentin, Berman, Lin: Rcan1 negatively regulates Fc epsilonRI-mediated signaling and mast cell function. in The Journal of experimental medicine 2009 (PubMed)

  6. Human Polyclonal RCAN1 Primary Antibody for ELISA, WB - ABIN1451085 : Fuentes, Pritchard, Estivill: Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene. in Genomics 1997 (PubMed)

More Antibodies against Regulator of Calcineurin 1 Interaction Partners

Xenopus laevis Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. RCAN1-regulated vascular branching which may play a role in the patterning of morphologically different vasculature.

Human Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. elucidated a novel function of regulator of calcineurin 1 isoform 1 in mitochondria and provides a molecular basis for the regulator of calcineurin 1 isoform over-expression-induced mitochondrial dysfunctions and neuronal apoptosis

  2. our research revealed that RCAN1 was involved in the development of small cell lung cancer, and it might be a cancer-inhibiting gene for the formation of bone metastases in small cell lung cancer

  3. The results of the study indicate that RCAN1 is suppressed in endothelial cells of chronically inflamed periodontal tissues. During an acute infection, however, rcan1 seems to be upregulated in endothelial cells, indicating a modulating role in immune homeostasis of periodontal tissues.

  4. mRNA expression levels of DSCR1 and VEGF-C (show VEGFC Antibodies), and microvessel density are increased in cancerous tissues, compared with paracancerous tissue in hypopharyngeal cancer.

  5. DSC1 expression is significantly downregulated in human masticatory mucosa during wound healing

  6. Increased expression of DSC1 can promote the occurrence of head and neck squamous cell carcinoma (HNSCC) and is associated with tumor. The increased expression of DSC1 also indicates a poor prognosis of the patients with HNSCC.

  7. The objective of this study was aimed to detect the association of Down syndrome critical region 1 (DSCR1) gene polymorphisms (rs149048873 and rs143081213) and congenital heart disease (CHD (show CHDH Antibodies)) susceptibility.

  8. Results support overexpression of RCAN1 and particularly the RCAN1.1S isoform during aging as a pathogenic mechanism in both Down syndrome-related and sporadic Alzheimer's disease

  9. RCAN1 can interact with IkappaBalpha (show NFKBIA Antibodies) and affect the phosphorylation of IkappaBalpha (show NFKBIA Antibodies) at tyrosine 42.

  10. The sequence variations in RCAN1 promoter are not major genetic factors involved in sporadic CHD (show CHDH Antibodies), at least in the current research population.

Mouse (Murine) Regulator of Calcineurin 1 (RCAN1) interaction partners

  1. The present study demonstrates that RCAN1 deficiency protects against Salmonella intestinal infection by enhancing proinflammatory JNK (show MAPK8 Antibodies) signaling.

  2. DSCR1 as a key protein that couples axon growth.

  3. from amongst the myriad of gene expression changes occurring in Type 2 diabetes (T2D) b-cells where we had little knowledge of which changes cause b-cell dysfunction, we applied a trisomy 21 screening approach which linked RCAN1 to b (show TDO2 Antibodies)-cell mitochondrial dysfunction in T2D.

  4. These results uncover a critical link between calcineurin (show PPP3CA Antibodies) signalling, impaired neurotrophin (show BDNF Antibodies) trafficking and neurodevelopmental deficits in the peripheral nervous system in Down syndrome.

  5. Data suggest that expression of Dscr1 in hippocampus can be regulated by dietary factors; supplementation of maternal diet and offspring diet with fish oil down-regulates Dscr1 in hippocampus of offspring; Dscr1 is a presumed target in Down syndrome.

  6. inhibition of the calcineurin (show PPP3CA Antibodies)-nuclear factor of activated T cells pathway enhances the proliferation of granulocyte-monocyte progenitors both in vitro and in vivo

  7. PACAP (show ADCYAP1 Antibodies) targets RCAN1 to control neuronal differentiation.

  8. We also confirmed that overexpression of RCAN1-1L could inhibit the transcriptional activation of an NFAT (show NFATC1 Antibodies)-dependent promoter in response to PMA and ionomycin by inhibiting Calcineurin (show PPP3CA Antibodies) activity in HEK293T cells

  9. found that RCAN1/3 interact with RAF (show RAF1 Antibodies) kinases and CN in a non-exclusive manner. Our data suggests that the balance of RCAN interactions with CN and/or RAF (show RAF1 Antibodies) kinases may influence T cell positive selection

  10. Calcineurin (show PPP3CA Antibodies) and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

Regulator of Calcineurin 1 (RCAN1) Antigen Profile

Antigen Summary

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Alternative names and synonyms associated with Regulator of Calcineurin 1 (RCAN1)

  • regulator of calcineurin 1 (RCAN1) antibody
  • regulator of calcineurin 1b (rcan1b) antibody
  • Down syndrome critical region gene 1 (dscr1) antibody
  • regulator of calcineurin 1 (rcan1) antibody
  • desmocollin 1 (DSC1) antibody
  • DSCR1-like protein (LOC443255) antibody
  • regulator of calcineurin 1 (Rcan1) antibody
  • 2410048A02Rik antibody
  • AA408855 antibody
  • Adapt78 antibody
  • AI429645 antibody
  • AL024459 antibody
  • AV028423 antibody
  • CALP1L antibody
  • CDHF1 antibody
  • CSP1 antibody
  • DG2/DG3 antibody
  • DSC1 antibody
  • Dscr1 antibody
  • Mcip1 antibody
  • MGC53636 antibody
  • MGC69428 antibody
  • rcan1 antibody
  • RCN1 antibody
  • wu:fr92c05 antibody

Protein level used designations for RCAN1

regulator of calcineurin 1 , Down syndrome critical region gene 1 , cadherin family member 1 , desmocollin-1 , desmosomal glycoprotein 2/3 , calcipressin-1 , down syndrome critical region protein 1 , Down syndrome candidate region 1 , calcium and oxidant-inducible mRNA , modulatory calcineurin-interacting protein 1 , myocyte-enriched calcineurin-interacting protein 1 , near DSCR proline-rich protein , Down syndrome critical region homolog 1 , calcineurin inhibitor , calcipressin 1 , down syndrome critical region protein 1 homolog , myocyte-enriched calcineurin interactin protein 1 , Down syndrome critical region protein 1 homolog , Oxidative-induced protein Adapt78

697108 Macaca mulatta
336348 Danio rerio
380353 Xenopus laevis
448016 Xenopus (Silurana) tropicalis
1823 Homo sapiens
443255 Ovis aries
1827 Homo sapiens
54720 Mus musculus
379550 Xenopus laevis
418510 Gallus gallus
607887 Canis lupus familiaris
539640 Bos taurus
266766 Rattus norvegicus
100171642 Pongo abelii
100689474 Cricetulus griseus
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