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anti-Mouse (Murine) SIX4 Antibodies:
anti-Human SIX4 Antibodies:
anti-Rat (Rattus) SIX4 Antibodies:
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Human Monoclonal SIX4 Primary Antibody for IF, ELISA - ABIN565685
Qamar, Deitsch, Patrick, Post, Spillman, Iwanaga, Thorburn, Ford, Behbakht: Specificity and prognostic validation of a polyclonal antibody to detect Six1 homeoprotein in ovarian cancer. in Gynecologic oncology 2012
significant co-localization of binding sites for MyoD (show MYOD1 Antibodies) and Six proteins on over a thousand mouse genomic DNA regions, were found.
The results indicated that low Six4 and Six5 gene dosage improved dystrophic phenotypes of Dmd(mdx (show DMD Antibodies)) /Y mice by enhancing muscle regeneration, and suggested that SIX4 and SIX5 are potentially useful de novo targets in therapeutic applications against muscle disorders, including DMD (show DMD Antibodies).
results reveal a role for Six4 during adult muscle regeneration and suggest a widespread mechanism of cooperation between Six4 and MyoD (show MYOD1 Antibodies).
the transcription factors Six1 (show SIX1 Antibodies) and Six4 are required for male gonadal differentiation.
Direct molecular regulation of the myogenic determination gene Myf5 (show MYF5 Antibodies) by Pax3 (show PAX3 Antibodies), with modulation by Six1 (show SIX1 Antibodies)/4 factors, is exemplified by the -111 kb-Myf5 (show MYF5 Antibodies) enhancer
Data show that absence of Six1 (show SIX1 Antibodies) and Six4 leads to the development of dorsal myofibers lacking expression of fast-type muscle genes, and mainly expressing a slow-type muscle program.
These results suggest that Six1 (show SIX1 Antibodies) and Six4 genes are expressed in the taste bud cells, in newly formed or surviving type-II cells.
Six4 and Six5 repressed, while Six1 (show SIX1 Antibodies) activated myogenin (show MYOG Antibodies) expression, suggesting that the differential regulation of myogenin (show MYOG Antibodies) expression is responsible for the differential effects of Six genes
Six1 (show SIX1 Antibodies) and Six4 expression is required to specifically activate fast-type muscle genes
Data show that Six4 is transcriptional regulatory element X (TrexBF) in skeletal myocytes and transactivates the muscle creatine kinase (show CKM Antibodies) enhancer.
This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells.
homeobox protein SIX4
, sine oculis homeobox homolog 4
, sine oculis-related homeobox 4 homolog
, skeletal muscle-specific ARE-binding protein AREC3