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Browse our SPAG9 Proteins (SPAG9)

Full name:
Sperm Associated Antigen 9 Proteins (SPAG9)
On www.antibodies-online.com are 4 Sperm Associated Antigen 9 (SPAG9) Proteins from 3 different suppliers available. Additionally we are shipping SPAG9 Antibodies (57) and SPAG9 Kits (4) and many more products for this protein. A total of 69 SPAG9 products are currently listed.
Synonyms:
3110018C07Rik, 4733401I23Rik, 4831406C20Rik, AW552012, CT89, HLC-6, HLC4, JIP-4, Jip4, JLP, JSAP2, JSAP2a, Mapk8ip4, PHET, PIG6, syd1
list all proteins Gene Name GeneID UniProt
SPAG9 9043 O60271
SPAG9 70834 Q58A65
Rat SPAG9 SPAG9 360600  

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SPAG9 Proteins (SPAG9) by Origin

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Human Sperm Associated Antigen 9 (SPAG9) interaction partners

  1. SPAG9 mRNA and protein overexpression in lung cancer tissue, and the presence of SPAG9 IgG antibody in peripheral blood of lung cancer patients indicates that it has potential as a biomarker for lung cancer diagnosis.

  2. SPAG9-elevated expression contributes to malignant behavior and poor prognosis of breast cancer and may support a potential indicator in treatment selection.

  3. Study suggest that suppression of miR (show MLXIP Proteins)-141 may cause an aberrant overexpression of SPAG9 promoting growth and metastasis of hepatocellular carcinoma cells.

  4. expression of SPAG9 in ECC cells with TGF-beta1 (show TGFB1 Proteins) treatment and spheroids formation was increased

  5. PLK1 binding to JIP4 was found in G2 phase and mitosis, and PLK1 binding was self-primed by PLK1 phosphorylation of JIP4.

  6. Based on in vitro assays, we found miR (show MLXIP Proteins)-200a-3p significantly inhibit cancer cell proliferation by inducing apoptosis.

  7. FOXK1 protein levels and activity are regulated by associating with JLP and PLK1

  8. SPAG9 overexpression in gastric cancer correlates with poor prognosis and contributes to gastric cancer cell proliferation

  9. SPAG9 was upregulated in nonmelanoma skin cancer when compared with normal skin.

  10. SPAG9 expression is significantly increased in prostate cancer and it may be involved in the process of prostate cancer cell motility, migration and angiogenesis.

Mouse (Murine) Sperm Associated Antigen 9 (SPAG9) interaction partners

  1. data establish JSAP1 and JLP as positive regulators of kinesin-1-dependent axonal transport, which prevents neuronal degeneration.

  2. JSAP1 and JLP play critical roles in kinesin-1-dependent axonal transport

  3. JSAP1 and JLP, which might be paralogous to each other, are critical and functionally redundant in cytokinesis and control ARF6 (show ARF6 Proteins) localization to the midbody by forming a tripartite complex of JSAP1/JLP, active ARF6 (show ARF6 Proteins), and kinesin-1.

  4. JLP in skin basal keratinocytes plays an important role in UVB-induced apoptosis by modulating p38 MAPK (show MAPK14 Proteins) signaling pathways.

  5. Data indicate a role of a scaffolding protein JLP in the regulation of surface CD40 (show CD40 Proteins) expression and fine-tuning of dendritic cell (DC) function.

  6. A functional role for JLP in the gep (show GRN Proteins) oncogene (show RAB1A Proteins)-regulated neoplastic signaling pathway.

  7. describe a protein, JLP, which acts as a scaffolding protein to bring mitogen-activated protein kinases and their target transcription factors together for the execution of specific signaling pathways

  8. The JIP4 scaffold protein (show HOMER1 Proteins) therefore appears to be a new component of the p38 MAP kinase (show MAPK14 Proteins) signaling pathway

  9. analysis of a novel protein-protein interaction between KLC1 and JLP that involves leucine zipper-like domains

  10. Ablation of the scaffold protein (show HOMER1 Proteins) JLP causes reduced fertility in male mice.

SPAG9 Protein Profile

Protein Summary

This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with SPAG9

  • JNK-associated leucine-zipper protein (Bm1_41390)
  • sperm associated antigen 9 (SPAG9)
  • sperm associated antigen 9 (spag9)
  • sperm associated antigen 9 (Spag9)
  • 3110018C07Rik protein
  • 4733401I23Rik protein
  • 4831406C20Rik protein
  • AW552012 protein
  • CT89 protein
  • HLC-6 protein
  • HLC4 protein
  • JIP-4 protein
  • Jip4 protein
  • JLP protein
  • JSAP2 protein
  • JSAP2a protein
  • Mapk8ip4 protein
  • PHET protein
  • PIG6 protein
  • syd1 protein

Protein level used designations for SPAG9

JNK-associated leucine-zipper protein , sperm associated antigen 9 , C-Jun-amino-terminal kinase-interacting protein 4 , C-Jun-amino-terminal kinase-interacting protein 4-like , c-Jun-amino-terminal kinase-interacting protein 4-like , JNK interacting protein , JNK/SAPK-associated protein , Max-binding protein , c-Jun NH2-terminal kinase-associated leucine zipper protein , cancer/testis antigen 89 , human lung cancer oncogene 6 protein , lung cancer oncogene 4 , mitogen-activated protein kinase 8-interacting protein 4 , proliferation-inducing gene 6 , protein highly expressed in testis , sperm surface protein , sunday driver 1 , JIP-4 , JNK-interacting leucine zipper , JNK-interacting protein 4 , JNK/SAPK-associated protein 2 , sperm-associated antigen 9

GENE ID SPECIES
6103159 Brugia malayi
422095 Gallus gallus
455131 Pan troglodytes
480557 Canis lupus familiaris
540689 Bos taurus
707613 Macaca mulatta
100012908 Monodelphis domestica
100070202 Equus caballus
100088678 Ornithorhynchus anatinus
100186844 Ciona intestinalis
100221658 Taeniopygia guttata
100406944 Callithrix jacchus
100465355 Ailuropoda melanoleuca
9043 Homo sapiens
70834 Mus musculus
360600 Rattus norvegicus
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