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Human TNC ELISA Kit for Sandwich ELISA - ABIN415118
Celik, Gunebakmaz, Baran, Dogdu, Elcik, Kobat, Balin, Erdem, Aydin, Ozdogru, Topsakal: An investigation of tenascin-C levels in rheumatic mitral stenosis and their response to percutaneous mitral balloon valvuloplasty. in Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012
Show all 5 Pubmed References
Human TNC ELISA Kit for Sandwich ELISA - ABIN457079
Karata?, Baysal, Sap, Alt?n, Çiçekler: The role of tenascin-C and oxidative stress in rheumatic and congenital heart valve diseases: an observational study. in Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 2013
Show all 2 Pubmed References
Rat (Rattus) TNC ELISA Kit for Sandwich ELISA - ABIN431614
Salamanna, Frizziero, Pagani, Giavaresi, Curzi, Falcieri, Marini, Abruzzo, Martini, Fini: Metabolic and cytoprotective effects of in vivo peri-patellar hyaluronic acid injections in cultured tenocytes. in Connective tissue research 2015
Results suggest that sequence variants in TNC and COL5A1 (show COL5A1 ELISA Kits) genes are associated with superficial digital flexor tendinopathy in TB racehorses. In
Tenascin-C protein expression in this muscle was confined to arterioles and venules (80% of cases) and increased after training in A-allele carriers. Prior to training, volume densities of subsarcolemmal and myofibrillar mitochondria in m. vastus lateralis muscle were 49% and 18%, respectively, higher in A/A homozygotes relative to T-nucleotide carriers (A/T and T/T)
Study that recombinant TNC consisting of the epidermal growth factor (EGF (show EGF ELISA Kits)-like repeats induced cerebral arterial constriction via EGF receptor (show EGFR ELISA Kits) and activation of ERK1/2 (show MAPK1/3 ELISA Kits)
Tenascin-C was abundant in cortical white and gray matter in brain tissue from Alzheimer's Disease patients.
Overexpression of TNC, SMA (show SMN1 ELISA Kits), and vimentin (show VIM ELISA Kits) were significantly correlated with the lower overall survival in prostate cancer patients.
Gain- and loss-of-function xenograft manipulations demonstrated that a mutant IDH1 (show IDH1 ELISA Kits) restricts glioma aggression by reducing HIF1alpha (show HIF1A ELISA Kits)-dependent TNC expression to decrease extracellular matrix stiffness and mechanosignalling.
analysis of SNPs in tenascin-C (TNC) associated with degenerative rotator cuff tears
High TNC expression is associated with retinoblastoma.
prepartum and postpartum TN-C serum levels significantly higher in mild and severe preeclampsia than in healthy pregnancy
Tenascin-C overexpression in cancer cells and stromal fibroblasts was an independent poor prognostic factor for overall survival and disease-free survival esophageal squamous cell carcinoma patients.
Serum TNC levels are significantly raised and correlate with various clinical and laboratory variables of disease activity in children with enthesitis-related arthritis
Study suggests that tenascin-C (TnC) contributes to the regulation of structural plasticity in the cerebellum and that interactions between TnC and matrix metalloproteinase 9 (show MMP9 ELISA Kits) are likely to be important for these processes to occur.
the exact role of TNC in primary tumor growth
A deficiency of tenascin C interferes with Th1 (show HAND1 ELISA Kits) and Th17 cells, protecting animals from experimental autoimmune encephalomyelitis.
Tenascin-C may be an important mediator in the development of brain edema and blood-brain barrier disruption following subarachnoid hemorrhage, mechanisms for which may involve MAPK (show MAPK1 ELISA Kits)-mediated MMP-9 (show MMP9 ELISA Kits) induction and ZO-1 (show TJP1 ELISA Kits) degradation
TN-C aggravates autoimmune myocarditis by driving the dendritic cell activation and Th17 differentiation via toll-like receptor 4 (show TLR4 ELISA Kits).
TNC supports the stress-induced expression of extracellular matrix that reinforce the aorta and the stress-induced excessive inflammatory response in the aorta.
TNC plays an important role in TMJ wound healing, especially for wounds generated by mechanical stress.
Tenascin-C is required for normal Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling in the whisker follicle stem cell niche.
TNC downregulates Dickkopf-1 (DKK1 (show DKK1 ELISA Kits)) promoter activity through the blocking of actin stress fiber formation, activates Wnt (show WNT2 ELISA Kits) signaling, and induces Wnt (show WNT2 ELISA Kits) target genes in tumor and endothelial cells.
The increased levels of elastin (show ELN ELISA Kits), type V collagen (show COL5A1 ELISA Kits) and tenascin C are probably the result of increased expression by fibroblastic cells; reversely, elastin (show ELN ELISA Kits) influences myofibroblast differentiation
TNC does not appear to contribute directly to outflow resistance in the eye.
TNC could be a potential candidate gene for meat quality traits in pigs.
tenascin binds to fibronectin (show FN1 ELISA Kits) at a cryptic binding site
Reloading of atrophied rat soleus muscle induces tenascin-C expression around damaged muscle fibers. Increase of rat soleus muscle loading modifies basement membrane of damaged muscle fibers through ectopic endomysial expression of tenascin-C.
tenascin-C is part of a specialized extracellular matrix in the region of the horizontal myoseptum that influences the growth of motor axons
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.
, tenascin C (hexabrachion)
, GP 150-225
, glioma-associated-extracellular matrix antigen
, hexabrachion (tenascin)
, myotendinous antigen
, tenascin-C isoform 14/AD1/16