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Human Polyclonal YBX1 Primary Antibody for IF, WB - ABIN1882002
Osada, Uno, Mineta, Kameoka, Takahashi, Terao: Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta. in Molecular ecology 2010
Show all 5 Pubmed References
Human Polyclonal YBX1 Primary Antibody for IF (p), IHC (p) - ABIN675683
Wang, Sun, Gu, Li, Zhang, Chi, Hao: shRNA-Mediated Silencing of Y-Box Binding Protein-1 (YB-1) Suppresses Growth of Neuroblastoma Cell SH-SY5Y In Vitro and In Vivo. in PLoS ONE 2015
Show all 2 Pubmed References
Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366502
Stickeler, Fraser, Honig, Chen, Berget, Cooper: The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. in The EMBO journal 2001
Human Polyclonal YBX1 Primary Antibody for ICC, IF - ABIN4366500
Dey, Robitaille, Remke, Maier, Malhotra, Gregorieff, Wrana, Taylor, Angers, Kenney: YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. in Oncogene 2016
TCTP (show TPT1 Antibodies) interacted with Y-box-binding protein 1 (YBX1), and their interaction was localized to the N-terminal region of TCTP (show TPT1 Antibodies) and the 1-129 amino acid (aa) residues of YBX1. The interaction of TCTP (show TPT1 Antibodies) with YBX1 might cooperate or coordinate their functions in the control of diverse regulatory pathways in cancer cells.
YB-1 expression promotes pancreatic cancer metastasis that is inhibited by microRNA-216a.
findings point to YB-1 and NSUN2 (show NSUN2 Antibodies) as possible mediators of the process of transfer of specific mRNAs into exosomes, allowing us to speculate on an involvement of these proteins in the mRNA sorting via the recognition of the above motifs
YB-1 is induced by Shh (show SHH Antibodies) in CGNPs
FOXO3a (show FOXO3 Antibodies) nuclear expression was inversely correlated with YB-1 nuclear expression in prostate cancer tissues.
these findings define a mechanism of drug resistance through which YBX1 contributes to antiestrogen bypass in breast cancer cells
High YB1 expression is associated with Cisplatin Resistance in Gastric Cancer.
Using mass spectrometry analysis, this study discovered a distinct phosphorylation site, Ser (show SIGLEC1 Antibodies)-176, on YBX1. Overexpression of the YBX1-S176A (serine-to-alanine) mutant in either HEK293 cells or colon cancer HT29 cells showed dramatically reduced NF-kappaB (show NFKB1 Antibodies)-activating ability compared with that of WT-YBX1, confirming that Ser (show SIGLEC1 Antibodies)-176 phosphorylation is critical for the activation of NF-kappaB (show NFKB1 Antibodies) by YBX1.
Collectively, these findings demonstrate a novel role of YBX1 in maintaining the stemness of CSCs and metastasis, unveiling YBX1 as promising therapeutic target for NSCLC treatments.
These studies reveal the functional role of YB-1 in the Angiogenin (show ANG Antibodies)-mediated stress response program.
The amounts of YB-1 and YB-1 mRNA in rabbit organs and several cell lines.
results prove direct inhibitory action of YB-1 on its mRNA translation, while the positive effect of PABP (show PABPC1 Antibodies) is realized through displacing YB-1 from the regulatory element
this study shows that innate immunity activation by muramyl peptides is mediated via an interaction between YB1 and NOD2 (show NOD2 Antibodies)
In conclusion, TGF-beta (show TGFB1 Antibodies) signaling pathway may influence liver fibrosis by incorporating with YB-1, indicating that YB-1 could be a potential target for therapies against liver fibrosis.
Reduction in the expression of YBX1 and ILF3 (show MMP4 Antibodies) controls the expression of pluripotency-related genes in ESCs (show NR2E3 Antibodies), suggesting their roles in further regulation of the pluripotent state of ESCs (show NR2E3 Antibodies).
In the initial stage of myocyte differentiation, transcription of the YB-1 gene was regulated by E2F1 (show E2F1 Antibodies) and Sp1 (show SP1 Antibodies), and was then gradually replaced under the control of both MyoD (show MYOD1 Antibodies) and myogenin (show MYOG Antibodies).
YB-1 is a novel intracellular target of activated protein C (show PROC Antibodies) in renal ischemia-reperfusion injury
miR (show MLXIP Antibodies)-382 inhibits osteosarcoma metastasis and relapse by targeting YB-1 protein.
YB-1 was revealed in a population of Cajal bodies in 2-cell mouse embryos but not in other cells studied.
The effects of MIA/CD-RAP (show MIA Antibodies) on transcriptional regulation in chondrocytes, through the regulation of p54(nrb (show NONO Antibodies)) via YBX1 contributes to the understanding of chondrogenesis.
The formation of intracytoplasmic Gag-RNA complexes is facilitated by YB-1, which promotes MMTV virus assembly.
transcription factor; acts as a regulator of protein tyrosine phosphatase PTP1B expression
B box-binding protein
, CCAAT-binding transcription factor I subunit A
, DNA-binding protein B
, Y-box transcription factor
, Y-box-binding protein 1
, enhancer factor I subunit A
, major histocompatibility complex, class II, Y box-binding protein I
, nuclease sensitive element binding protein 1
, nuclease-sensitive element-binding protein 1
, CCAAT-binding transcription factor 1 subunit A
, DNA binding protein B
, Y box transcription factor
, enhancer factor 1 alpha
, enhancer factor 1 subunit A
, FRG Y
, frg y1
, frog Y-box proteins
, Y-box binding protein 1