You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our DGCR8 (DGCR8) ELISA Kits

Full name:
DiGeorge Syndrome Critical Region Gene 8 ELISA Kits (DGCR8)
On www.antibodies-online.com are 0 DiGeorge Syndrome Critical Region Gene 8 (DGCR8) ELISA Kits from different suppliers available. Additionally we are shipping DGCR8 Antibodies (92) and DGCR8 Proteins (5) and many more products for this protein. A total of 109 DGCR8 products are currently listed.
Synonyms:
C22orf12, D16H22S788E, D16H22S1742E, D16Wis2, DGCR8, DGCRK6, Gy1, MGC78846, N41, pasha, si:ch211-106a19.4, Vo59c07, wu:fc23f08, wu:fc38f06
list all ELISA KIts Gene Name GeneID UniProt
Human DGCR8 DGCR8 54487 Q8WYQ5
Mouse DGCR8 DGCR8 94223 Q9EQM6
Rat DGCR8 DGCR8 287954  

Show all synonyms

More ELISA Kits for DGCR8 Interaction Partners

Human DiGeorge Syndrome Critical Region Gene 8 (DGCR8) interaction partners

  1. Results demonstrated that DGCR8 is significantly upregulated in invasive ductal breast carcinoma, suggesting that increased expression of DGCR8 may play a fundamental role during the process of breast carcinogenesis.

  2. DGCR8 and Drosha (show DROSHA ELISA Kits) assemble into a heterotrimeric complex on RNA, comprising two DGCR8 molecules and one Drosha (show DROSHA ELISA Kits) molecule.

  3. Results show that DGCR8 forms an alternative complex with the RRP6-containing form of the exosome, acts as an adaptor to recruit the exosome to target structured RNAs, and the DGCR8/hRRP6 complex controls the stability of human telomerase RNA.

  4. We aimed to evaluate the expression of the major components of microRNA biogenesis machinery including Drosha (show DROSHA ELISA Kits), Dicer (show DICER1 ELISA Kits) and DiGeorge syndrome critical region gene 8 (DGCR8) in multiple sclerosis patients

  5. These results reveal a new pathway in the DNA damage response wherein ABL (show ABL1 ELISA Kits)-dependent tyrosine phosphorylation of DGCR8 stimulates the processing of selective primary miRNAs.

  6. DGCR8 functions as an oncogene (show RAB1A ELISA Kits) in ovarian cancer, which is in part mediated by miR (show MLXIP ELISA Kits)-27b.

  7. Together with a 23-amino acid peptide from DGCR8, DROSHA (show DROSHA ELISA Kits) constitutes a minimal functional core. DROSHA (show DROSHA ELISA Kits) serves as a "ruler" by measuring 11 bp from the basal ssRNA-dsRNA junction. DGCR8 interacts with the stem and apical elements through its dsRNA-binding domains and RNA-binding heme domain, respectively, allowing efficient and accurate processing.

  8. Data show decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome

  9. These data show that hepatitis B virus proteins repress DGCR8 promoter activity by upregulating the expression of transcription factor YY1 (show YY1 ELISA Kits).

  10. in tumors with DGCR8 E518K and DROSHA (show DROSHA ELISA Kits) exon 29 (miRNAPG-HS) mutations ... greater prevalence of tumors with blastemal predominant histology in patients with miRNAPG-HS and/or SIX1 (show SIX1 ELISA Kits)/2 Q177R mutations

Mouse (Murine) DiGeorge Syndrome Critical Region Gene 8 (DGCR8) interaction partners

  1. DGCR8 is required for the progression, but not initiation, of Akt (show AKT1 ELISA Kits) induced prostate cancer in vivo.

  2. DGCR8 is required for microRNA biogenesis and normal mouse embryonic stem cell proliferation and differentiation.

  3. These results reveal a new pathway in the DNA damage response wherein ABL (show ABL1 ELISA Kits)-dependent tyrosine phosphorylation of DGCR8 stimulates the processing of selective primary miRNAs.

  4. Conditional gene deletion of the essential miRNA-processing enzyme Dgcr8 in the developing renal tubular system results in severe developmental defects and kidney failure.

  5. Dgcr8 is responsible for modulation of gene expression programs underlying myelin formation and maintenance as well as suppression of an injury-related gene expression program

  6. Dgcr8 mutant mice, which have a defective miRNA pathway while retaining an intact endo-siRNA pathway, were infertile and displayed cumulative defects in meiotic and haploid phases of spermatogenesis, resulting in oligo-, terato-, and azoospermia.

  7. Adipose tissue-specific Dgcr8 knockout mice displayed enlarged but pale interscapular brown fat with decreased expression of genes characteristic of brown fat and were intolerant to cold exposure.

  8. Data indicate that DiGeorge syndrome critical region gene 8 (DGCR8)-dependent miRs are indispensable for osteoclastic control of bone metabolism.

  9. This suggests that Dgcr8-microRNA-Drd2 (show DRD2 ELISA Kits)-dependent thalamocortical disruption is a pathogenic event underlying schizophrenia-associated psychosis.

  10. These data reveal a role for DeltaNp63 in the transcriptional regulation of DGCR8 to reprogram adult somatic cells into multipotent stem cells.

DGCR8 Antigen Profile

Antigen Summary

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with DGCR8

  • DiGeorge syndrome critical region gene 8 (dgcr8) Elisa Kit
  • DiGeorge syndrome critical region gene 8 (DGCR8) Elisa Kit
  • DGCR8 microprocessor complex subunit (dgcr8) Elisa Kit
  • DiGeorge syndrome critical region gene 8 (LOC100351620) Elisa Kit
  • DGCR8 microprocessor complex subunit (DGCR8) Elisa Kit
  • DiGeorge syndrome critical region gene 8 (Dgcr8) Elisa Kit
  • C22orf12 Elisa Kit
  • D16H22S788E Elisa Kit
  • D16H22S1742E Elisa Kit
  • D16Wis2 Elisa Kit
  • DGCR8 Elisa Kit
  • DGCRK6 Elisa Kit
  • Gy1 Elisa Kit
  • MGC78846 Elisa Kit
  • N41 Elisa Kit
  • pasha Elisa Kit
  • si:ch211-106a19.4 Elisa Kit
  • Vo59c07 Elisa Kit
  • wu:fc23f08 Elisa Kit
  • wu:fc38f06 Elisa Kit

Protein level used designations for DGCR8

hypothetical protein LOC432110 , DiGeorge syndrome critical region gene 8 , DiGeorge syndrome critical region 8 , microprocessor complex subunit DGCR8 , diGeorge syndrome critical region 8 homolog , DiGeorge syndrome critical region 8 homolog

GENE ID SPECIES
432110 Xenopus laevis
458659 Pan troglodytes
100144670 Xenopus (Silurana) tropicalis
100351620 Oryctolagus cuniculus
54487 Homo sapiens
94223 Mus musculus
486416 Canis lupus familiaris
100616094 Sus scrofa
540254 Bos taurus
287954 Rattus norvegicus
563963 Danio rerio
416785 Gallus gallus
Did you look for something else?