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Browse our Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) ELISA Kits

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Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator ELISA Kits (PRKRA)
On www.antibodies-online.com are 0 Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) ELISA Kits from different suppliers available. Additionally we are shipping Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Antibodies (89) and Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Proteins (11) and many more products for this protein. A total of 110 Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator products are currently listed.
Synonyms:
AV120107, dyt16, im:7151758, lear, pact, PRK, PRKRA, prkra-a, prkra-b, rax, rbpa, zgc:162619
list all ELISA KIts Gene Name GeneID UniProt
Mouse PRKRA PRKRA 23992 Q9WTX2
Rat PRKRA PRKRA 311130 Q4V8C7
Human PRKRA PRKRA 8575 O75569

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More ELISA Kits for Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator Interaction Partners

Mouse (Murine) Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. Data (including data from studies in transgenic/knockout mice) suggest that PACT/RAX (protein activator of protein kinase (show CDK7 ELISA Kits) R) functions as negative regulator of PKR/Eif2ak2 (show EIF2AK2 ELISA Kits) (protein kinase (show CDK7 ELISA Kits) R) in development of postnatal anterior pituitary tissue.

  2. Deficiency of PKR (show EIF2AK2 ELISA Kits) diminished peripheral inflammatory responses following E. coli

  3. The protein kinase (show CDK7 ELISA Kits) PKR (show EIF2AK2 ELISA Kits) is critical for LPS (show TLR4 ELISA Kits)-induced iNOS (show NOS2 ELISA Kits) production but is dispensable for inflammasome activation in macrophages.

  4. These observations identified a specific mutation that reduces steady-state levels of RAX (show RAX ELISA Kits) protein and disrupts the dsRNA binding function of the protein, demonstrating the importance of the Prkra gene in various aspects of mouse development.

  5. RAX (show RAX ELISA Kits) phosphorylation at serine 18 is required for PKR (show EIF2AK2 ELISA Kits) activation and consequent translation inhibition

  6. Study demonstrated an essential role of PACT (show RBBP6 ELISA Kits) in mammalian ear development and produced the first animal model.

  7. The role of PACT (show RBBP6 ELISA Kits) in mediating gene induction, PKR (show EIF2AK2 ELISA Kits) activation, and apoptosis in response to diverse stimuli

  8. TRBP (show TARBP2 ELISA Kits) controls PACT (show RBBP6 ELISA Kits) activation of PKR (show EIF2AK2 ELISA Kits), an activity that is reversed by stress.

  9. The authors demonstrate for the first time that PACT (show RBBP6 ELISA Kits) is phosphorylated in response to tunicamycin and is responsible for PKR (show EIF2AK2 ELISA Kits) activation by direct interaction.

  10. Study revealed a physiologically significant role for PACT (show RBBP6 ELISA Kits) in cell proliferation and an essential role of a dsRNA-binding protein in mammalian pituitary expansion.

Human Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR (show PKLR ELISA Kits) Activator PACT (show RBBP6 ELISA Kits) in Human Hepatic Stellate Cells.

  2. The interferon (show IFNA ELISA Kits)-induced protein kinase (show CDK7 ELISA Kits)(PACT (show RBBP6 ELISA Kits)) partially rescued defects of interferon (show IFNA ELISA Kits)-beta1 and chemokine (C-C motif) ligand 5/RANTES (show CCL5 ELISA Kits) (regulated on activation normal T cell expressed and secreted) induction in DDX3 (show DDX3X ELISA Kits)-knockdown HEK293 cells.

  3. These findings support a model in which a measles virus defective interfering RNA is sensed by PACT (show RBBP6 ELISA Kits) and RIG-I (show DDX58 ELISA Kits) to initiate an innate antiviral response via activation of interferon-beta (show IFNB1 ELISA Kits) production.

  4. this study demonstrates for the first time that OV20.0 of Orf virus is also able to interact with the dsRNA binding domain of PACT (show RBBP6 ELISA Kits) and that the presence of dsRNA strengthened the interaction of these two molecules.

  5. the affinity of PACT-PACT (show RBBP6 ELISA Kits) and PACT (show RBBP6 ELISA Kits)-PKR (show PKLR ELISA Kits) interactions is enhanced in dystonia patient lymphoblasts, thereby leading to intensified PKR (show PKLR ELISA Kits) activation and enhanced cellular death.

  6. Altered PRKRA signalling and C / EBPbeta expression is associated with HLA-B27 expression in monocytic cells.

  7. This stuidy provides the first independent replication of the DYT16 locus at 2q31.2 and strongly confirms the causal contribution of the PRKRA gene to DYT16. Our data suggest worldwide involvement of PRKRA in dystonia.

  8. NS1 (show PTPN11 ELISA Kits) prevents PACT (show RBBP6 ELISA Kits) from interacting with an essential component of the virus.

  9. PKR (show PKLR ELISA Kits) is activated in uninfected cells, specifically during mitosis, by binding to dsRNAs formed by inverted Alu repeats (IRAlus).

  10. In contrast to its previously described activity, PACT (show RBBP6 ELISA Kits) contributes to PKR (show PKLR ELISA Kits) dephosphorylation during HIV-1 replication.

Cow (Bovine) Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) interaction partners

  1. Tumour necrosis factor alpha (show TNF ELISA Kits) up-regulates protein kinase (show CDK7 ELISA Kits) R (PKR (show EIF2AK2 ELISA Kits))-activating protein (PACT, PRKRA) and increases phosphorylation of PKR (show EIF2AK2 ELISA Kits) and eukaryotic initiation factor (show EIF4G1 ELISA Kits) 2-alpha in articular chondrocytes.

Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA) Antigen Profile

Antigen Summary

This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA)

  • protein kinase, interferon-inducible double stranded RNA dependent activator (PRKRA) Elisa Kit
  • protein kinase, interferon-inducible double stranded RNA dependent activator (LOC100354780) Elisa Kit
  • protein kinase, interferon inducible double stranded RNA dependent activator (Prkra) Elisa Kit
  • protein kinase, interferon-inducible double stranded RNA dependent activator (prkra) Elisa Kit
  • AV120107 Elisa Kit
  • dyt16 Elisa Kit
  • im:7151758 Elisa Kit
  • lear Elisa Kit
  • pact Elisa Kit
  • PRK Elisa Kit
  • PRKRA Elisa Kit
  • prkra-a Elisa Kit
  • prkra-b Elisa Kit
  • rax Elisa Kit
  • rbpa Elisa Kit
  • zgc:162619 Elisa Kit

Protein level used designations for PRKRA

protein kinase, interferon-inducible double stranded RNA dependent activator , interferon-inducible double stranded RNA-dependent protein kinase activator A-like , PKR-associated protein X , PKR-associating protein X , interferon-inducible double stranded RNA-dependent protein kinase activator A , protein activator of the interferon-induced protein kinase , protein kinase, interferon-inducible double stranded RNA-dependent activator , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog , double-stranded RNA-binding protein A , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog A , interferon-inducible double stranded RNA-dependent protein kinase activator A homolog B , xlRBPA

GENE ID SPECIES
459776 Pan troglodytes
703063 Macaca mulatta
100155653 Sus scrofa
100354780 Oryctolagus cuniculus
100477392 Ailuropoda melanoleuca
100596448 Nomascus leucogenys
23992 Mus musculus
311130 Rattus norvegicus
8575 Homo sapiens
488423 Canis lupus familiaris
282875 Bos taurus
557370 Danio rerio
379187 Xenopus laevis
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