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Browse our RAN (RAN) ELISA Kits

Full name:
RAN, Member RAS Oncogene Family ELISA Kits (RAN)
On www.antibodies-online.com are 1 RAN, Member RAS Oncogene Family (RAN) ELISA Kits from 1 different suppliers available. Additionally we are shipping RAN Antibodies (145) and RAN Proteins (17) and many more products for this protein. A total of 175 RAN products are currently listed.
Synonyms:
AAF30287, ARA24, CG1404, Dmel\CG1404, dran, fc16b04, Gsp1, l(1)G0075, M2, ran, ran-1, Ran/M2, ran10A, RANP1, Rasl2-9-ps, TC4, wu:fc16b04, xran
list all ELISA KIts Gene Name GeneID UniProt
Human RAN RAN 5901 P62826
Rat RAN RAN 84509 P62828
Mouse RAN RAN 19384 P62827

Show all synonyms

More ELISA Kits for RAN Interaction Partners

Xenopus laevis RAN, Member RAS Oncogene Family (RAN) interaction partners

  1. This study identifies TPX2 as the only direct RanGTP target and NEDD1 (show NEDD1 ELISA Kits) as the only Aurora A (show AURKA ELISA Kits) substrate essential for the activation of the RanGTP-dependent microtubule nucleation pathway.

  2. Experiments in Xenopus assembly extracts with M9M, a superaffinity nuclear localization sequence that displaces cargoes bound by transportin, or TLB, a mutant transportin that can bind cargo and RanGTP simultaneously, support direct inhibition.

  3. Examination of H1 histones reveals isoform-specific regulation by Cdk1 (show CDK1 ELISA Kits) and RanGTP

  4. Data show that importin-beta (show KPNB1 ELISA Kits) binds to Apc (show APC ELISA Kits) and negatively regulates the MT-assembly and spindle-promoting activity of Apc (show APC ELISA Kits) in a Ran-regulatable manner.

  5. results demonstrate that distinctly from its role in spindle assembly, RanGTP maintains spindle microtubules in anaphase through the local activation of ISWI and that this is essential for proper chromosome segregation

Fruit Fly (Drosophila melanogaster) RAN, Member RAS Oncogene Family (RAN) interaction partners

  1. the Canoe Ras-association (RA) domains directly bind RanGTP

  2. Knockdown of the small G protein Ran, which is essential for nuclear transport, leads to an arrest of EcR in the cytoplasm, but does not prevent efficient nuclear import of the most important heterodimerization partner of EcR, ultraspiracle (Usp).

  3. results demonstrate that distinctly from its role in spindle assembly, RanGTP maintains spindle microtubules in anaphase through the local activation of ISWI and that this is essential for proper chromosome segregation

  4. gtpase ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos

  5. anillin (show ANLN ELISA Kits) and Peanut are involved in pseudocleavage furrow ingression in syncytial embryos, a process that is regulated by Ran

Human RAN, Member RAS Oncogene Family (RAN) interaction partners

  1. FGF2 (show FGF2 ELISA Kits) nuclear translocation is regulated by Karyopherin-beta2 and Ran GTPase in human glioblastoma cells

  2. Enterovirus 71-induced downregulation of miR (show MLXIP ELISA Kits)-197 expression increased the expression of RAN, which supported the nuclear transport of the essential viral proteins 3D/3CD and host protein hnRNP K (show HNRNPK ELISA Kits) for viral replication.

  3. Inter-cellular transport of ran GTPase

  4. Data show that RNA-binding protein (show PTBP1 ELISA Kits) LIN28B (show LIN28B ELISA Kits) coordinates the expression of the oncogene (show RAB1A ELISA Kits) RAN protein and aurora A kinase (AURKA (show AURKA ELISA Kits)) in neuroblastoma (show ARHGEF16 ELISA Kits).

  5. Elevated metaphase RanGTP levels use Ubr5 (show UBR5 ELISA Kits) to couple overall chromosome congression to SAC (show ADCY10 ELISA Kits) silencing.

  6. Data show that importin-beta (show KPNB1 ELISA Kits) (impbeta) alters the nuclear pore's permeability in a Ran-dependent manner, suggesting that impbeta is a functional component of the nuclear pore complex (NPC (show NPC1 ELISA Kits)).

  7. RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 (show XPO7 ELISA Kits) and TPX2 (show TPX2 ELISA Kits) have roles in serous epithelial ovarian cancer

  8. comparison of the GTPase reaction of the slower hydrolyzing GTPase Ran with Ras

  9. Ran silencing did not affect the A375 invasive capability, while it was enhanced in 526 cells, suggesting that Ran knockdown, by AurkA (show AURKA ELISA Kits) down-regulation, resulted in a Ran-independent enhanced melanoma cell invasion.

  10. stress can disrupt the Ran gradients through RCC1-dependent and RCC1-independent mechanisms

Mouse (Murine) RAN, Member RAS Oncogene Family (RAN) interaction partners

  1. Data suggest Ran activation by RanBP1 (show RANBP1 ELISA Kits) in macrophages promotes Legionella phagosome formation and phagocytosis; LegG1 functions as bacterial Ran activator, localizes to phagosomes, and promotes microtubule stabilization, phagocytosis, and replication.

  2. Augmented expression of Ran in progranulin (show GRN ELISA Kits)-deficient neurons restores nuclear TDP-43 (show TARDBP ELISA Kits) levels and improves their survival.

  3. Reduction in Ran levels causes cytoplasmic decrease and nuclear accumulation of importin alpha (show KPNA4 ELISA Kits) leading to cellular senescence in normal cells.

  4. a novel connection between the hyper-activation of the small GTPase Ran and the matricellular protein SMOC-2 (show SMOC2 ELISA Kits) that has important consequences for oncogenic transformation.

  5. A critical function of RanBP2 (show RANBP2 ELISA Kits) is to capture recycling RanGTP-importin-beta (show KPNB1 ELISA Kits) complexes at cytoplasmic fibrils to allow for adequate classical nuclear localization signal-mediated cargo import.

  6. Downregulation of the Ran GTPase effector RanBP1 (show RANBP1 ELISA Kits) is required for nuclear reorganisation.

  7. Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation.

  8. intracellular Ran protein levels control the nuclear retention for selective transcription factors such as c-Jun (show JUN ELISA Kits) and c-Fos of AP-1 (show JUN ELISA Kits), which is known to be critical in T cell activation and proliferation and lymphokine (show IL2 ELISA Kits) secretion.

  9. expression of Ran/M1 (show TLR4 ELISA Kits) and Ran/M2 increased in pachytene spermatocytes with progressive transcript accumulation until they reached the round spermatid stage, in the seminiferous epithelium of adults

  10. RanGDP is regulated by phosphorylation and regulated by NTF2 (show NUTF2 ELISA Kits)

RAN Antigen Profile

Antigen Summary

RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1). Mutations in RAN disrupt DNA synthesis. Because of its many functions, it is likely that RAN interacts with several other proteins. RAN regulates formation and organization of the microtubule network independently of its role in the nucleus-cytosol exchange of macromolecules. RAN could be a key signaling molecule regulating microtubule polymerization during mitosis. RCC1 generates a high local concentration of RAN-GTP around chromatin which, in turn, induces the local nucleation of microtubules. RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor. Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy). RAN coactivation of the AR diminishes with polyglutamine expansion within the AR, and this weak coactivation may lead to partial androgen insensitivity during the development of Kennedy's disease.

Alternative names and synonyms associated with RAN

  • RAN, member RAS oncogene family (ran) Elisa Kit
  • RAN, member RAS oncogene family (RAN) Elisa Kit
  • CG1404 gene product from transcript CG1404-RA (ran) Elisa Kit
  • RAN, member RAS oncogene family (ran-1) Elisa Kit
  • RAN, member RAS oncogene family (Ran) Elisa Kit
  • RAS-like, family 2, locus 9 (Rasl2-9) Elisa Kit
  • ras-related nuclear protein (ran) Elisa Kit
  • AAF30287 Elisa Kit
  • ARA24 Elisa Kit
  • CG1404 Elisa Kit
  • Dmel\CG1404 Elisa Kit
  • dran Elisa Kit
  • fc16b04 Elisa Kit
  • Gsp1 Elisa Kit
  • l(1)G0075 Elisa Kit
  • M2 Elisa Kit
  • ran Elisa Kit
  • ran-1 Elisa Kit
  • Ran/M2 Elisa Kit
  • ran10A Elisa Kit
  • RANP1 Elisa Kit
  • Rasl2-9-ps Elisa Kit
  • TC4 Elisa Kit
  • wu:fc16b04 Elisa Kit
  • xran Elisa Kit

Protein level used designations for RAN

GTP-binding nuclear protein Ran , GTPase Ran , ras-like protein TC4 , ras-related nuclear protein , RAN, member RAS oncogene family , ran GTP-binding protein , CG1404-PA , CG1404-PB , Ran GTPase , ran-PA , ran-PB , OK/SW-cl.81 , RanGTPase , androgen receptor-associated protein 24 , guanosine triphosphatase Ran , member RAS oncogene family , RAN, member RAS oncogene family pseudogene 1 , GTP-binding nuclear protein Ran, testis-specific isoform , RAS-like, family 2, locus 9, pseudogene

GENE ID SPECIES
448091 Xenopus (Silurana) tropicalis
452414 Pan troglodytes
100173539 Pongo abelii
100189578 Xenopus laevis
100302079 Ovis aries
100499482 Canis lupus familiaris
44072 Drosophila melanogaster
379874 Xenopus laevis
5901 Homo sapiens
540457 Bos taurus
84509 Rattus norvegicus
442976 Canis lupus familiaris
19384 Mus musculus
396193 Gallus gallus
397655 Sus scrofa
19428 Mus musculus
30572 Danio rerio
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