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Mapped six genes (EIF4G3, HSP90 (show HSP90AB1 ELISA Kits), RBBP6, IL8 (show IL8 ELISA Kits), TERT (show TERT ELISA Kits), and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization.
this study shows that PACT is an essential coactivator of the MDA5 (show IFIH1 ELISA Kits)-dependent type I IFN response to viral RNA
High PRKRA (show PRKRA ELISA Kits) mRNA expression is associated with colorectal cancer.
It was established in this report that interactions between PACT, ADAR1 (show ADAR ELISA Kits) and HIV-1-encoded Tat (show TAT ELISA Kits) protein diminish the activation of PKR (show PKLR ELISA Kits) in response to HIV-1 infection.
5 genomic variants in GSC (show GSC ELISA Kits), HOXA2 (show HOXA2 ELISA Kits) and PRKRA (show PRKRA ELISA Kits) were identified through mutational analysis in Chinese patients with microtia.
These results suggest that the RBBP6-3 isoform may be involved in promoting apoptosis in cancerous cells.
RBBP6 is a candidate gene for myeloproliferative neoplasms (MPNs) susceptibility in a subset of pedigrees with familial MPN (show PRSS27 ELISA Kits).
MicroRNA-122 Inhibits the Production of Inflammatory Cytokines by Targeting the PKR (show PKLR ELISA Kits) Activator PACT in Human Hepatic Stellate Cells.
The interferon (show IFNA ELISA Kits)-induced protein kinase (show CDK7 ELISA Kits)(PACT) partially rescued defects of interferon (show IFNA ELISA Kits)-beta1 and chemokine (C-C motif) ligand 5/RANTES (show CCL5 ELISA Kits) (regulated on activation normal T cell expressed and secreted) induction in DDX3 (show DDX3X ELISA Kits)-knockdown HEK293 cells.
These findings support a model in which a measles virus defective interfering RNA is sensed by PACT and RIG-I (show DDX58 ELISA Kits) to initiate an innate antiviral response via activation of interferon-beta (show IFNB1 ELISA Kits) production.
this study demonstrates for the first time that OV20.0 of Orf virus is also able to interact with the dsRNA binding domain of PACT and that the presence of dsRNA strengthened the interaction of these two molecules.
P2P-R expression may be translationally regulated by PUM2 and that P2P-R may modulate translation by influencing ribosomal protein gene expression
the PACT-p53 (show TP53 ELISA Kits) interaction plays a critical role in embryonic development and tumorigenesis and identify PACT as a member of negative regulators of p53 (show TP53 ELISA Kits).
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
E3 ubiquitin-protein ligase RBBP6
, retinoblastoma binding protein 6
, retinoblastoma-binding protein 6
, retinoblastoma-binding protein 6-like
, PKR-associated protein X
, PKR-associating protein X
, interferon-inducible double stranded RNA-dependent protein kinase activator A
, protein activator of the interferon-induced protein kinase
, protein kinase, interferon-inducible double stranded RNA-dependent activator
, RB-binding Q-protein 1
, p53-associated cellular protein of testis
, proliferation potential-related protein
, protein P2P-R
, retinoblastoma-binding Q protein 1