• Matrix metalloproteinases reduce beta-2-adrenergic receptor density and cause spontaneous hypertension

Cardiovascular diseases (CVD) are among the prime causes for mortality in the Western world. A main challenge to the research community on diseases related to CVD, which include acute myocardial infarction, unstable angina and other life-threatening pathologies, is a sufficiently sensitive diagnosis of these conditions. antibodies-online.com offers a broad range of products that have been tested not only against the antigen they were developed for but also in “real-life” situations, i.e. on human tissues. A main cause for a dramatic increase in CVD is the metabolic syndrome, which includes a range of disorders that increase the risk for developing CVD. Among them are type 2 diabetes mellitus, obesity, and insulin resistance which are potentially leading to high blood pressure, abnormal cholesterol levels, glucose intolerance and inflammatory disorders. All of them are risk factors for the development of CVD, especially when combined with life style choices like smoking, a diet high in saturated fats, carbohydrates and sodium, along with a sedentary life style. Due to the increase in these behaviors and life-style choices even among the young, obesity and CVD have spread to ever younger demographics.