Browse our anti-GRIN2B (GRIN2B) Antibodies

Full name:
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B Antibodies (GRIN2B)
On www.antibodies-online.com are 391 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) Antibodies from 26 different suppliers available. Additionally we are shipping GRIN2B Kits (22) and GRIN2B Proteins (10) and many more products for this protein. A total of 432 GRIN2B products are currently listed.
Synonyms:
AW490526, GluN2B, hNR3, MRD6, Nmdar2b, nr2b
list all antibodies Gene Name GeneID UniProt
GRIN2B 2904 Q13224
GRIN2B 24410 Q00960
GRIN2B 14812 Q01097

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Top referenced anti-GRIN2B Antibodies

  1. Human Monoclonal GRIN2B Primary Antibody for BI, IF - ABIN967955 : Fallon, Moreau, Croft, Labib, Gu, Fon: Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for 967955

  2. Human Polyclonal GRIN2B Primary Antibody for IF - ABIN401598 : Liu, Murray, Jones: Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 4 references for 401598

  3. Human Polyclonal GRIN2B Primary Antibody for IF - ABIN401622 : Browning, Wang, Lanker, Jobe: Electroshock- and pentylenetetrazol-induced seizures in genetically epilepsy-prone rats (GEPRs): differences in threshold and pattern. in Epilepsy research 1990 (PubMed)
    Show all 3 references for 401622

  4. Rat (Rattus) GRIN2B Primary Antibody for ELISA, WB - ABIN1742592 : Strack, McNeill, Colbran: Mechanism and regulation of calcium/calmodulin-dependent protein kinase II targeting to the NR2B subunit of the N-methyl-D-aspartate receptor. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 1742592

  5. Human Polyclonal GRIN2B Primary Antibody for IF (p), IHC (p) - ABIN744368 : Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014 (PubMed)
    Show all 2 references for 744368

  6. Human Polyclonal GRIN2B Primary Antibody for ELISA, WB - ABIN1533143 : Mandich, Schito, Bellone, Antonacci, Finelli, Rocchi, Ajmar: Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. in Genomics 1994 (PubMed)

  7. Human Monoclonal GRIN2B Primary Antibody for ICC, IHC - ABIN261572 : Ramberger, Peschl, Schanda, Irschick, Höftberger, Deisenhammer, Rostásy, Berger, Dalmau, Reindl: Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay. in PLoS ONE 2015 (PubMed)

  8. Cow (Bovine) Polyclonal GRIN2B Primary Antibody for IHC, WB - ABIN2776121 : Cais, Sedlacek, Horak, Dittert, Vyklicky: Temperature dependence of NR1/NR2B NMDA receptor channels. in Neuroscience 2008 (PubMed)

  9. Rat (Rattus) Polyclonal GRIN2B Primary Antibody for ELISA, WB - ABIN185658 : Arning, Kraus, Valentin, Saft, Andrich, Epplen: NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. in Neurogenetics 2005 (PubMed)

More Antibodies against GRIN2B Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) interaction partners

  1. Results indicate that the GRIN2B single nucleotide polymorphisms rs890 might be associated with schizophrenia in the Chinese Han population.

  2. These in vivo changes reflect changes in glutamate transporter (show SLC1A1 Antibodies) protein (show HNRNPU Antibodies) in Huntington's disease (HD), mice and human HD post-mortem (show NLRP1 Antibodies)tissue. Furthermore, NAC was able to rescue (show GRIN1 Antibodies)changes in key glutamate receptor proteins related to excitotoxicity in HD, including NMDAR2B.

  3. Genetic association of CYP2B6 (show CYP2B6 Antibodies)*6 and GRIN2B (rs1019385 and rs1806191) single-nucleotide polymorphisms and ketamine-induced EP occurrence.

  4. most rare variants in GluN2A (show GRIN2A Antibodies) were associated with epilepsy, whereas GluN2B variants were associated with intellectual disability with or without seizures

  5. In this review, mutations in GRIN2B were described as distributed throughout the entire gene in patients with neuropsychiatric and developmental disorders.

  6. Genetic variants were found in GluN2B from patients with neurological or psychiatric disorders resulting in reduced surface expression of GluN2B.

  7. Results found that GluN2B subunit-containing NMDARs were dominant in induced pluripotent stem cell-derived neurons and that tyrosine-protein kinase Fyn (show FYN Antibodies) potentiated the function of GluN2B subunit-containing NMDARs.

  8. Multiple genetic variants in GRIN2B are jointly associated with gene expression, prefrontal function and behaviour during working memory (WM). These results support the role of GRIN2B genetic variants in WM prefrontal activity in human adults.

  9. Findings do not support a role for GRIN2B variants in altering response to clozapine in our sample of European patients with schizophrenia deemed resistant or intolerant to treatment

  10. both Arf6 (show ARF6 Antibodies) activation through GluN2B-BRAG1 (show IQSEC2 Antibodies) during early development and the transition from BRAG1 (show IQSEC2 Antibodies)- to BRAG2 (show IQSEC1 Antibodies)-dependent Arf6 (show ARF6 Antibodies) signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) interaction partners

  1. HumanTau(AT) causes excitotoxicity mediated by NR2B-containing NMDA receptors due to enhanced extracellular glutamate (show GRIN1 Antibodies).

  2. The NR2B-CREB (show CREB1 Antibodies)-miR212/132-CRTC1 (show CRTC1 Antibodies)-CREB (show CREB1 Antibodies) signal network plays an important role in the regulation of pain.

  3. This study demonstrated that Increasing the GluN2A (show GRIN2A Antibodies)/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

  4. These in vivo changes reflect changes in glutamate transporter (show SLC1A1 Antibodies) protein (show LAPTM4A Antibodies) in HD mice and human HD post-mortem tissue. Furthermore, NAC (show NLRP1 Antibodies) was able to rescue changes in key glutamate (show GRIN1 Antibodies) receptor proteins related to excitotoxicity in HD, including NMDAR2B.

  5. Data show that hydroxyproline HyP (show PHEX Antibodies)(10) plays a critical role in maintaining the structural integrity of conantokins conRl-B, which can be correlated with its glutamate (show GRIN1 Antibodies) receptor, ionotropic, N-methyl D-aspartate 2B (GluN2B) subunit-selective inhibition.

  6. These results highlight the requirement for stringent pharmacogenetic approaches to separate specific on-target effects from nonspecific off-target effects. Importantly, they also demonstrate that the CaMKII (show CAMK2G Antibodies)/GluN2B interaction is required not only for normal long-term potentiation induction but also for the maintenance of synaptic strength.

  7. GluN2B-dependent calcium signaling and excitatory postsynaptic current, long-term depression, and spatial reversal learning are enhanced in the hippocampus of AC6 (show ADCY6 Antibodies)(-/-) mice without altering the gross anatomy of the brain

  8. Unpredictable chronic mild stress mice exhibited elevated nucleus accumbens (NAC (show NLRP1 Antibodies)) shell levels of Glun2B. GluN2b levels were also lower within the NAC (show NLRP1 Antibodies) core.

  9. These data suggest that chronic early postnatal SSS influences spatial learning and memory ability, levels of hippocampal NR2B, and NR2A (show GRIN2A Antibodies)/NR2B ratios in adult males.

  10. Results identify crucial determinants in the C-terminal domain of GluN2B subunits in promoting neuronal death in ischemic conditions.

GRIN2B Antigen Profile

Antigen Summary

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Alternative names and synonyms associated with GRIN2B

  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (Grin2b) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (grin2b) antibody
  • glutamate receptor, ionotropic, NMDA2B (epsilon 2) (Grin2b) antibody
  • AW490526 antibody
  • GluN2B antibody
  • hNR3 antibody
  • MRD6 antibody
  • Nmdar2b antibody
  • nr2b antibody

Protein level used designations for GRIN2B

NMDA type glutamate receptor , N-methyl D-aspartate receptor subtype 2B , N-methyl-D-aspartate receptor subunit 2B , NMDAR2B , NR2B , glutamate [NMDA] receptor subunit epsilon-2 , glutamate receptor ionotropic, NMDA 2B , N-methyl-D-aspartate receptor subunit 3 , NR3 , glutamate receptor subunit epsilon-2 , glutamate receptor, ionotropic, NMDA2B , N-methyl-D-aspartate receptor subunit NR2B , GluRepsilon2 , N-methyl D-aspartate receptor 2B

GENE ID SPECIES
751956 Taeniopygia guttata
494009 Canis lupus familiaris
2904 Homo sapiens
24410 Rattus norvegicus
100127347 Xenopus laevis
14812 Mus musculus
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