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Browse our anti-GRIN2B (GRIN2B) Antibodies

Full name:
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B Antibodies (GRIN2B)
On www.antibodies-online.com are 398 Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) Antibodies from 25 different suppliers available. Additionally we are shipping GRIN2B Kits (19) and GRIN2B Proteins (10) and many more products for this protein. A total of 436 GRIN2B products are currently listed.
Synonyms:
AW490526, GluN2B, hNR3, MRD6, Nmdar2b, nr2b
list all antibodies Gene Name GeneID UniProt
GRIN2B 2904 Q13224
GRIN2B 24410 Q00960
GRIN2B 14812 Q01097

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Top referenced anti-GRIN2B Antibodies

  1. Human Polyclonal GRIN2B Primary Antibody for IHC (fro), IP - ABIN372682 : Carroll, Zukin: NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. in Trends in neurosciences 2002 (PubMed)
    Show all 16 references for ABIN372682

  2. Cow (Bovine) Polyclonal GRIN2B Primary Antibody for IHC (fro), WB - ABIN372684 : Itoh, Matsumoto, Inoue: Spherical aberration correction suitable for a wavefront controller. in Optics express 2009 (PubMed)
    Show all 10 references for ABIN372684

  3. Human Polyclonal GRIN2B Primary Antibody for WB - ABIN372683 : Alvestad, Grosshans, Coultrap, Nakazawa, Yamamoto, Browning: Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. in The Journal of biological chemistry 2003 (PubMed)
    Show all 9 references for ABIN372683

  4. Human Monoclonal GRIN2B Primary Antibody for BI, IF - ABIN967955 : Fallon, Moreau, Croft, Labib, Gu, Fon: Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN967955

  5. Human Polyclonal GRIN2B Primary Antibody for IF - ABIN401598 : Liu, Murray, Jones: Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 4 references for ABIN401598

  6. Rat (Rattus) GRIN2B Primary Antibody for ELISA, WB - ABIN1742592 : Strack, McNeill, Colbran: Mechanism and regulation of calcium/calmodulin-dependent protein kinase II targeting to the NR2B subunit of the N-methyl-D-aspartate receptor. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for ABIN1742592

  7. Rat (Rattus) Polyclonal GRIN2B Primary Antibody for ELISA, WB - ABIN185658 : Arning, Kraus, Valentin, Saft, Andrich, Epplen: NR2A and NR2B receptor gene variations modify age at onset in Huntington disease. in Neurogenetics 2005 (PubMed)

  8. Human Polyclonal GRIN2B Primary Antibody for ELISA, WB - ABIN1532371 : Mandich, Schito, Bellone, Antonacci, Finelli, Rocchi, Ajmar: Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. in Genomics 1994 (PubMed)

  9. Human Monoclonal GRIN2B Primary Antibody for ICC, IHC - ABIN261572 : Ramberger, Peschl, Schanda, Irschick, Höftberger, Deisenhammer, Rostásy, Berger, Dalmau, Reindl: Comparison of diagnostic accuracy of microscopy and flow cytometry in evaluating N-methyl-D-aspartate receptor antibodies in serum using a live cell-based assay. in PLoS ONE 2015 (PubMed)

  10. Dog (Canine) Polyclonal GRIN2B Primary Antibody for IHC, WB - ABIN2776121 : Cais, Sedlacek, Horak, Dittert, Vyklicky: Temperature dependence of NR1/NR2B NMDA receptor channels. in Neuroscience 2008 (PubMed)

More Antibodies against GRIN2B Interaction Partners

Human Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) interaction partners

  1. Genetic variants were found in GluN2B from patients with neurological or psychiatric disorders resulting in reduced surface expression of GluN2B.

  2. Results found that GluN2B subunit-containing NMDARs were dominant in induced pluripotent stem cell-derived neurons and that tyrosine-protein kinase Fyn (show FYN Antibodies) potentiated the function of GluN2B subunit-containing NMDARs.

  3. Multiple genetic variants in GRIN2B are jointly associated with gene expression, prefrontal function and behaviour during working memory (WM). These results support the role of GRIN2B genetic variants in WM prefrontal activity in human adults.

  4. Findings do not support a role for GRIN2B variants in altering response to clozapine in our sample of European patients with schizophrenia deemed resistant or intolerant to treatment

  5. both Arf6 (show ARF6 Antibodies) activation through GluN2B-BRAG1 (show IQSEC2 Antibodies) during early development and the transition from BRAG1 (show IQSEC2 Antibodies)- to BRAG2 (show IQSEC1 Antibodies)-dependent Arf6 (show ARF6 Antibodies) signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses.

  6. GRIN2B (rs7301328) was significantly associated with disruptive behavior in adolescents.

  7. GRIN2B polymorphisms do not influence Parkinson disease age of onset in the US Caucasian population.

  8. GluN2B appears to exhibit allosteric regulation/inhibition by two distinct classes of antagonists; data from in silico docking suggest that GluN2B-selective antagonists broadly divide into two distinct classes according to binding pose.

  9. Knockdown of PKD1 (show PKD1 Antibodies) did not affect NMDAR (show GRIN1 Antibodies) internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR (show GRIN1 Antibodies)-mediated synaptic functions.

  10. GRIN2B encodes the NR2 subunit of NMDA receptors, which are a class of ionotropic glutamate (show GRIN1 Antibodies) receptors involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission.

Mouse (Murine) Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B) interaction partners

  1. GluN2B-dependent calcium signaling and excitatory postsynaptic current, long-term depression, and spatial reversal learning are enhanced in the hippocampus of AC6 (show ADCY6 Antibodies)(-/-) mice without altering the gross anatomy of the brain

  2. Unpredictable chronic mild stress mice exhibited elevated nucleus accumbens (NAC (show NLRP1 Antibodies)) shell levels of Glun2B. GluN2b levels were also lower within the NAC (show NLRP1 Antibodies) core.

  3. These data suggest that chronic early postnatal SSS influences spatial learning and memory ability, levels of hippocampal NR2B, and NR2A (show GRIN2A Antibodies)/NR2B ratios in adult males.

  4. Results identify crucial determinants in the C-terminal domain of GluN2B subunits in promoting neuronal death in ischemic conditions.

  5. both Arf6 (show ARF6 Antibodies) activation through GluN2B-BRAG1 (show IQSEC2 Antibodies) during early development and the transition from BRAG1 (show IQSEC2 Antibodies)- to BRAG2 (show IQSEC1 Antibodies)-dependent Arf6 (show ARF6 Antibodies) signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses.

  6. The results suggest that NR2B vulnerability represents a target for environmental toxicants in the brain.

  7. Results show that monomeric Abeta1-42 application induces an increase of the Ca2 (show CA2 Antibodies)+-response and of the membrane expression of the extrasynaptic subunit of the NMDA receptor GluN2B in PC12 cells, while the opposite effects were observed in cultured neurons

  8. Results demonstrate that up-regulation of NR2B expression facilitates acquisition of auditory cued fear memory and enhances long-term potentiation at thalamus-lateral amygdala synapses

  9. Results suggest that EGFR (show EGFR Antibodies) signaling upregulates NMDA receptors through modification of the GluN2B subunit, and is required for high-frequency stimulation-induced long-term potentiation in the hippocampus

  10. Loss of GluN2B in principal neurons of the forebrain results in reduced punished food reward-seeking.

GRIN2B Antigen Profile

Antigen Summary

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Alternative names and synonyms associated with GRIN2B

  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (GRIN2B) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (Grin2b) antibody
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2B (grin2b) antibody
  • glutamate receptor, ionotropic, NMDA2B (epsilon 2) (Grin2b) antibody
  • AW490526 antibody
  • GluN2B antibody
  • hNR3 antibody
  • MRD6 antibody
  • Nmdar2b antibody
  • nr2b antibody

Protein level used designations for GRIN2B

NMDA type glutamate receptor , N-methyl D-aspartate receptor subtype 2B , N-methyl-D-aspartate receptor subunit 2B , NMDAR2B , NR2B , glutamate [NMDA] receptor subunit epsilon-2 , glutamate receptor ionotropic, NMDA 2B , N-methyl-D-aspartate receptor subunit 3 , NR3 , glutamate receptor subunit epsilon-2 , glutamate receptor, ionotropic, NMDA2B , N-methyl-D-aspartate receptor subunit NR2B , GluRepsilon2 , N-methyl D-aspartate receptor 2B

GENE ID SPECIES
751956 Taeniopygia guttata
494009 Canis lupus familiaris
2904 Homo sapiens
24410 Rattus norvegicus
100127347 Xenopus laevis
14812 Mus musculus
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