Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
It was proposed that FXYD1 (show FXYD1 ELISA Kits) plays a role in regulating AQP2 retention in apical membrane, and that this involves transfers between raft-like membrane domains in endosomes and plasma membranes.
Both NFATc3 (show NFATC3 ELISA Kits) knock-out mice and ILK (show ILK ELISA Kits) conditional-knockdown mice (cKD-ILK (show ILK ELISA Kits)) display symptoms of NDI (show AVPR2 ELISA Kits) (polyuria and reduced AQP2 expression).
aquaporin-2 regulates serine/threonine phosphatases in renal collecting duct
Ativation of LXRbeta (show NR1H2 ELISA Kits) increases AQP2 protein levels in the renal collecting ducts via a posttranscriptional mechanism top regulate water electrolyte balance.
PDZ domain-containing protein (show USH1C ELISA Kits) Sipa1l1 (signal-induced proliferation-associated 1 like 1 (show SIPA1L1 ELISA Kits)) binds to the cytoplasmic PDZ (show INADL ELISA Kits)-ligand motif of aquaporin-2 and accelerates its endocytosis in the absence of vasopressin (show AVP ELISA Kits)
Conditional inactivation of Elf5 (show ELF5 ELISA Kits) in the developing collecting ducts results in a small but significant reduction in the expression levels of Aqp2 and Avpr2 (show AVPR2 ELISA Kits) genes.
These results provide the direct evidence that the Ser (show SIGLEC1 ELISA Kits)-261 dephosphorylation is involved in the pS256- and pS269-related AQP2 regulation.
analysis of phosphorylation-dependent interactions of AQP2 with 14-3-3theta; and -zeta
the activation of CaSR (show CASR ELISA Kits) in the collecting duct prevents the cyclic AMP (show TMPRSS5 ELISA Kits)-dependent increase in AQP2-phosphorylation at S256 and water permeability, counteracting the short-term vasopressin (show AVP ELISA Kits) response.
Functional photoconvertible chimeric AQP-2 was successfully expressed in mpkCCD cells, in which forskolin induced apical trafficking and accumulation of chimeric AQP-2.
The present study provides detailed insights into the transport properties of AQP2 with the use of microsecond-scale molecular dynamics simulations, and explains how these channels conduct water molecules while at the same time excluding other molecules.
Data suggest that AQP2 binds LIP5 (show VTA1 ELISA Kits) in a AQP2-phosphorylation-dependent manner; phospho-mimicking mutations and phosphorylation reduce thermal stability of AQP2; AQP2 phosphorylation allosterically controls its interaction with LIP5 (show VTA1 ELISA Kits). [AQP2 = aquaporin 2; LIP5 (show VTA1 ELISA Kits) = LYST-interacting protein 5; LYST (show LYST ELISA Kits) = lysosomal trafficking regulator (show LYST ELISA Kits) protein]
The genetic variant rs426496 in AQP2; rs591810 in AQP3 (show AQP3 ELISA Kits) and rs1805127, rs1805128, and rs17173510, in KCNE1 (show KCNE1 ELISA Kits) were found in patients with Meniere's disease
An overview ofAQP2 mutations in genetic forms of nephrogenic diabetes insipidus (show AVPR2 ELISA Kits) (review)
Impaired endometrial receptivity in patients who underwent controlled ovarian stimulation is correlated with a decreased expression of AQP2.
Pretreatment with alkali (0.4 N NaOH) to disrupt exosome membranes allowed consistent ELISA measurements of urinary AQP2.
Findings indicate that SIRT1 (show SIRT1 ELISA Kits) increases AQP2 expression in TNF-alpha (show TNF ELISA Kits)-induced IMCD cells via the NF-kappaB (show NFKB1 ELISA Kits)-dependent signalling pathway, which might provide novel insight to understanding the renoprotective effects of SIRT1 (show SIRT1 ELISA Kits) in kidney diseases.
AQP2 polymorphisms (rs461872, rs7305534) were correlated with gastrointestinal toxicity of platinum-based chemotherapy in lung cancer patients
report a novel mutation of the AQP2 gene and highlight an important role of genetic testing for definite diagnosis
AQP1 (show AQP1 ELISA Kits), AQP2, and AQP3 (show AQP3 ELISA Kits), and V2R (show AVPR2 ELISA Kits) expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity
Aquaporin 2 promotes cell migration and epithelial morphogenesis.
Data provide evidence supporting the role of S256 and S269 in the maintenance of AQP2 at the cell surface.
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus.
ADH water channel
, collecting duct water channel protein
, water channel protein for renal collecting duct
, water-channel aquaporin 2