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Browse our CYP26B1 Proteins (CYP26B1)

Full name:
Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 Proteins (CYP26B1)
On are 6 Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1) Proteins from 4 different suppliers available. Additionally we are shipping CYP26B1 Antibodies (51) and CYP26B1 Kits (7) and many more products for this protein. A total of 71 CYP26B1 products are currently listed.
CP26, CYP26A2, cyp26b1, fc21d03, P450RAI-2, P450RAI2, RHFCA, wu:fc21d03, wu:fc26h10, zgc:76999
list all proteins Gene Name GeneID UniProt
CYP26B1 56603 Q9NR63
CYP26B1 232174 Q811W2
CYP26B1 312495 G3V7X8

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CYP26B1 Proteins (CYP26B1) by Origin

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More Proteins for CYP26B1 Interaction Partners

Xenopus laevis Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1) interaction partners

  1. Retinoic acid homeostasis regulates meiotic entry in developing anuran gonads and in Bidder's organ through Raldh2 (show ALDH1A2 Proteins) and Cyp26b1 proteins.

Human Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1) interaction partners

  1. There was increased expression of mRNA CYP26B1 in oral cancer tissue compared to adjacent noncancerous tissues.

  2. SNPs in three genes CYP26B1 rs2241057, CISD1 (show CISD1 Proteins) rs2251039, rs2590370, and TBX1 (show TBX1 Proteins) rs4819522 were involved in six potential pathways to influence serum prostate-specific antigen (show KLK3 Proteins) levels.

  3. Our results suggested that the CYP26B1 splice variant is associated with the occurrence of BQ-related oral cancer.

  4. homozygous carriers of the major (T) allele, relative to homozygous carriers of the minor (C) allele, of the CYP26B1 polymorphism rs2241057 may have an increased risk for the development of Crohn's disease.

  5. We report a 2p13.2 microdeletion in 2 subjects encompasing 2 genes, EXOC6B (show EXOC6B Proteins) and CYP26B12 with clinical effects on cognitive function, and craniofacial and skeletal development.

  6. Single nucleotide polymorphisms in CYP26B1, NANOS1 and STRA8 genes support involvement of meiotic program initiation genes in modifying the risk of azoospermia and oligozoospermia in a Han-Chinese population

  7. CYP26B1 capacity is genetically regulated and suggest that local CYP26B1 activity may influence atherosclerosis.

  8. Vascular cells express the spliced variant of CYP26B1 lacking exon 2 and it is also increased in atherosclerotic lesions

  9. Detection of the methylation prevalence of KCNA4 (show KCNA4 Proteins) and CYP26B1 together in serum demonstrated the good sensitivity and specificityin gastric cancer

  10. Human null and hypomorphic mutations were identified in the gene encoding the retinoic acid degrading enzyme CYP26B1 that lead to skeletal and craniofacial anomalies, including fusions of long bones, calvarial bone hypoplasia, and craniosynostosis

Mouse (Murine) Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1) interaction partners

  1. elimination of CYP26B1 activity within both germ and Sertoli cells resulted in severe male subfertility, with a loss of advanced germ cells from the seminiferous epithelium.

  2. The results of this study concluded that stimulus-dependent neuronal activity can control the expression of the RA catabolic enzyme Cyp26B1 and downstream genes such as BACE1 (show BACE Proteins).

  3. The study showed that a stimulus-dependent gradient of a retinoic acid-inactivating enzyme Cyp26B1 modifies the composition, localization

  4. Cyp26b1 in the growth plate regulates the proliferation rates of chondrocytes and is responsible for the normal function of the growth plate and growing bones

  5. results show that T cell-specific expression of Cyp26b1 is required for the development of T cell-mediated colitis and may be applicable to the development of therapeutics that target Cyp26b1 for the treatment of inflammatory bowel disease

  6. CYP26B1 suppresses two distinct genetic programs induced by retinoic acid: a Stra8-dependent meiotic pathway, and a Stra8-independent mitotic pathway.

  7. CYP26B1 has a role in regulating retinoid levels and is important for lymphatic vascular development in the mouse embryo

  8. Data demonstrated that CYP26B1 is essential during palatogenesis. The regulation of endogenous retinoic acid level through CYP26B1 is required for elevation of palatal shelves.

  9. Absence of Cyp26b1, a retinoic-acid-degrading enzyme, results in aberrant epidermal differentiation and filaggrin (show FLG Proteins) expression, defective cornified envelopes and skin barrier formation, in conjunction with peridermal retention.

  10. Cyp26b1 regulates retinoic acid signaling in spinal cord progenitor cell populations.

Zebrafish Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1) interaction partners

  1. The data demonstrate that RA-induced osteoblast-preosteocyte transitioning has multiple effects on developing bone in Cyp26b1 mutants, ranging from gain to loss of bone, depending on the allelic strength, the developmental stage and the cellular context.

  2. cyp26b1 is involved in limiting the activity of retinoic acid. Zygotic cyp26b1 was localized to presumptive rhombomere 3 and rhombomere 4 at early two-somite (2S) stage. Expression expands anteriorly to include rhombomere 2 at the 10S stage.

  3. effects of the inhibitor rather than excess retinoic acid most closely phenocopied the jaw defects seen with the Cyp26B1 morpholino

  4. Cyp26b1 is expressed within osteoblast cells, demonstrating that retinoic acid levels within these cells need to be tightly controlled

  5. cyp26b1 mutants may serve as a model to study the etiology of human vertebral disorders such as Klippel-Feil anomaly

CYP26B1 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with CYP26B1

  • cytochrome P450 26B1 (CpipJ_CPIJ002537)
  • cytochrome P450 26B1 (cyp26b1)
  • cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1)
  • cytochrome P450, family 26, subfamily B, polypeptide 1 (cyp26b1)
  • cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1)
  • cytochrome P450, family 26, subfamily b, polypeptide 1 (cyp26b1)
  • CP26 protein
  • CYP26A2 protein
  • cyp26b1 protein
  • fc21d03 protein
  • P450RAI-2 protein
  • P450RAI2 protein
  • RHFCA protein
  • wu:fc21d03 protein
  • wu:fc26h10 protein
  • zgc:76999 protein

Protein level used designations for CYP26B1

cytochrome P450 26B1 , cytochrome P450, family 26, subfamily B, polypeptide 1 , cytochrome P450 retinoic acid-inactivating 2 , cytochrome P450 retinoid metabolizing protein , cytochrome P450, subfamily XXVIB, polypeptide 1 , retinoic acid-metabolizing cytochrome , cytochrome P450, 26, retinoic acid B1 , cytochrome P450RAI-2 , retinoic acid B1 , retinoic acid hydroxylase , dol , stocksteif

6033808 Culex quinquefasciatus
100170648 Xenopus laevis
428809 Gallus gallus
780112 Xenopus (Silurana) tropicalis
56603 Homo sapiens
483120 Canis lupus familiaris
232174 Mus musculus
312495 Rattus norvegicus
324188 Danio rerio
540868 Bos taurus
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