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Browse our anti-MLL5 (MLL5) Antibodies

Full name:
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) Antibodies (MLL5)
On www.antibodies-online.com are 57 Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) (MLL5) Antibodies from 16 different suppliers available. A total of 61 MLL5 products are currently listed.
Synonyms:
1810033J14Rik, 9530077A04Rik, D230038D11Rik, HDCMC04P, Mll5
list all antibodies Gene Name GeneID UniProt
MLL5 55904 Q8IZD2
MLL5 69188 Q3UG20
MLL5 311968  

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Top referenced anti-MLL5 Antibodies

  1. Human Polyclonal MLL5 Primary Antibody for WB - ABIN658094 : Liu, Wang, Cheng, Liou, Deng: Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN658094

  2. Mouse (Murine) Polyclonal MLL5 Primary Antibody for EIA, IHC (fro) - ABIN1108255 : Heuser, Yap, Leung, de Algara, Tafech, McKinney, Dixon, Thresher, Colledge, Carlton, Humphries, Aparicio: Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. in Blood 2009 (PubMed)

More Antibodies against MLL5 Interaction Partners

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) (MLL5) interaction partners

  1. MLL5 preserves spindle bipolarity through maintaining cytosolic PLK1 (show PLK1 Antibodies) in a nonaggregated form.

  2. MLL5 interacts with OGT (show OGT Antibodies) and USP7 (show USP7 Antibodies) to form a stable ternary complex. Upregulation of MLL5 expression was correlated with increased expression of OGT (show OGT Antibodies) and USP7 (show USP7 Antibodies) in human primary cervical adenocarcinomas.

  3. Suggest a role for MLL5 and H3.3 in maintaining self-renewal hierarchies in adult glioblastomas.

  4. O-GlcNAcylation of MLL5beta at T440 residue is critical for MLL5 recruitment to the HPV16/18-long control region through its interaction with AP-1 (show FOSB Antibodies).

  5. Improved outcome is observed in decitabine-treated patients who express MLL5 at high levels.

  6. KMT2E expression retained association with poor acute promyelocytic leukaemia remission rate and shorter survival while the association with disease-free survival was of marginal significance.

  7. NMR solution structure of the MLL5 PHD (show PDC Antibodies) domain

  8. these results indicate that the suppression of MLL (show MLL Antibodies) genes, especially MLL2 (show MLL2 Antibodies) and MLL5, take part in modulating breast carcinogenesis.

  9. MLL5 is a cellular ligand for the natural cytotoxicity receptor NKp44 (show NCR2 Antibodies).

  10. findings provide first insights into the molecular basis for the recruitment, exclusion, and regulation of MLL5 at chromatin

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog, Drosophila) (MLL5) interaction partners

  1. inactivation of the Mll5 gene in mice results in a 30% reduction in the average representation of hematopoietic stem cells and in functional impairment of long-term hematopoietic repopulation potential under competitive conditions

  2. MLL5 is a key regulator of normal hematopoiesis

  3. findings establish several nonredundant functions for Mll5, including an essential role in regulating proliferation and functional integrity of hematopoietic stem/progenitor cells

  4. MLL5 plays an integral role in novel chromatin regulatory mechanisms that suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells.

MLL5 Antigen Profile

Antigen Summary

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.

Alternative names and synonyms associated with MLL5

  • myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) (MLL5) antibody
  • lysine (K)-specific methyltransferase 2E (KMT2E) antibody
  • lysine (K)-specific methyltransferase 2E (Kmt2e) antibody
  • 1810033J14Rik antibody
  • 9530077A04Rik antibody
  • D230038D11Rik antibody
  • HDCMC04P antibody
  • Mll5 antibody

Protein level used designations for MLL5

histone-lysine N-methyltransferase 2E , histone-lysine N-methyltransferase MLL5 , lysine N-methyltransferase 2E , myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia protein 5 , myeloid/lymphoid or mixed-lineage leukemia 5 , myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog

GENE ID SPECIES
100058928 Equus caballus
55904 Homo sapiens
69188 Mus musculus
311968 Rattus norvegicus
475895 Canis lupus familiaris
100628131 Sus scrofa
539121 Bos taurus
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