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Browse our anti-PRAME (PRAME) Antibodies

Full name:
anti-Preferentially Expressed Antigen in Melanoma Antibodies (PRAME)
On www.antibodies-online.com are 67 Preferentially Expressed Antigen in Melanoma (PRAME) Antibodies from 15 different suppliers available. Additionally we are shipping PRAME Proteins (18) and PRAME Kits (7) and many more products for this protein. A total of 104 PRAME products are currently listed.
Synonyms:
4930534P07Rik, CT130, MAPE, OIP-4, OIP4, PRAME
list all antibodies Gene Name GeneID UniProt
PRAME 23532 P78395
PRAME 75829  
PRAME 680000  

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Top referenced anti-PRAME Antibodies

  1. Human Polyclonal PRAME Primary Antibody for EIA, WB - ABIN453177 : Rezvani, Yong, Tawab, Jafarpour, Eniafe, Mielke, Savani, Keyvanfar, Li, Kurlander, Barrett: Ex vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia. in Blood 2009 (PubMed)
    Show all 3 references for ABIN453177

  2. Cow (Bovine) Polyclonal PRAME Primary Antibody for WB - ABIN2786466 : Sakakura, Kubo, Ako, Ikeda, Funayama, Hirahara, Sugawara, Yasu, Kawakami, Momomura: Determinants of in-hospital death and rupture in patients with a Stanford B aortic dissection. in Circulation journal : official journal of the Japanese Circulation Society 2007 (PubMed)
    Show all 2 references for ABIN2786466

  3. Human Polyclonal PRAME Primary Antibody for WB - ABIN2786465 : Roman-Gomez, Jimenez-Velasco, Agirre, Castillejo, Navarro, Jose-Eneriz, Garate, Cordeu, Cervantes, Prosper, Heiniger, Torres: Epigenetic regulation of PRAME gene in chronic myeloid leukemia. in Leukemia research 2007 (PubMed)

More Antibodies against PRAME Interaction Partners

Cow (Bovine) Preferentially Expressed Antigen in Melanoma (PRAME) interaction partners

  1. the expansion of the PRAME family occurred in both autosomes and sex chromosomes

Human Preferentially Expressed Antigen in Melanoma (PRAME) interaction partners

  1. PRAME is a downstream factor of SOX17 (show SOX17 Antibodies) and LIN28 (show LIN28A Antibodies) in regulating pluripotency and suppressing somatic/germ cell differentiation in primordial germ cells, germ cell neoplasia in situ, and seminomas.

  2. In line with its roles in controlling cell growth, RPAME regulates multiple critical cell-growth related genes, including IGF1R (show IGF1R Antibodies) oncogene (show RAB1A Antibodies). IGF1R (show IGF1R Antibodies) up-regulation contributes to increase of cell growth upon the knockdown of PRAME.

  3. This study demonstrates that PRAME functions as a tumor suppressor in breast cancer.

  4. PRAME is an independent prognostic biomarker in Uveal melanoma , which identifies increased metastatic risk in patients with Class 1 or disomy 3 tumors.

  5. Leukemias expressing high levels of PRAME had higher levels of cell death by regulating S100A4 (show S100A4 Antibodies)/p53 (show TP53 Antibodies) signaling.

  6. Our results suggest that the leukemias expressing high levels of PRAME has favorable prognosis

  7. PRAME expression is considered as a poor prognostic parameter in HL.

  8. PRAME immunoreactivity in myeloid leukemia (show BCL11A Antibodies) (ML) of Down syndrome (DS) is largely due to the non-blast components, while PRAME immunoreactivity in blasts of Transient abnormal myelopoiesis (TAM (show CCNA1 Antibodies)) is not restricted to cases that progress to ML of DS.

  9. This study shows the prognostic significance of PRAME expression in diffuse large B-cell lymphoma patients treated with R-CHOP (show DDIT3 Antibodies) therapy.

  10. results suggested that PRAME was a predictor for better outcome, could be a useful target for immunotherapy, and might represent a candidate marker for the monitoring of minimal residual disease

PRAME Antigen Profile

Antigen Summary

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Alternative names and synonyms associated with PRAME

  • preferentially expressed antigen in melanoma (PRAME) antibody
  • preferentially expressed antigen in melanoma (Prame) antibody
  • 4930534P07Rik antibody
  • CT130 antibody
  • MAPE antibody
  • OIP-4 antibody
  • OIP4 antibody
  • PRAME antibody

Protein level used designations for PRAME

preferentially expressed antigen in melanoma , Opa-interacting protein OIP4 , cancer/testis antigen 130 , melanoma antigen preferentially expressed in tumors , opa-interacting protein 4 , preferentially expressed antigen of melanoma

GENE ID SPECIES
528601 Bos taurus
23532 Homo sapiens
785023 Bos taurus
75829 Mus musculus
680000 Rattus norvegicus
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