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Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 ELISA Kits (SLC6A8)
On are 15 Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) ELISA Kits from 6 different suppliers available. Additionally we are shipping SLC6A8 Antibodies (43) and SLC6A8 Proteins (4) and many more products for this protein. A total of 69 SLC6A8 products are currently listed.
AA589632, Calregulin, cC1qR, CCDS1, CHOT1, CHT1, Creat, CRT, CRTR, CT1, RO, SLC6A8, SSA
list all ELISA KIts Gene Name GeneID UniProt
SLC6A8 811 P27797
SLC6A8 12317 P14211
SLC6A8 50690 P28570

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Top referenced SLC6A8 ELISA Kits

  1. Human SLC6A8 ELISA Kit for Sandwich ELISA - ABIN414440 : Gkaliagkousi, Gavriilaki, Nikolaidou, Chatzopoulou, Anyfanti, Triantafyllou, Petidis, Zamboulis, Douma: Association between cardiotrophin 1 levels and central blood pressure in untreated patients with essential hypertension. in American journal of hypertension 2014 (PubMed)
    Show all 4 references for 414440

  2. Rat (Rattus) SLC6A8 ELISA Kit for Sandwich ELISA - ABIN416125 : Chen, Hsieh, Peng, Peng: Exercise rescued chronic kidney disease by attenuating cardiac hypertrophy through the cardiotrophin-1 -> LIFR/gp 130 -> JAK/STAT3 pathway. in European journal of preventive cardiology 2014 (PubMed)
    Show all 2 references for 416125

More ELISA Kits for SLC6A8 Interaction Partners

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. C-CALR (show CALR ELISA Kits) in response to Ca2 (show CA2 ELISA Kits)+ undergoes conformational changes that trigger its function to export GR from the nucleus, resetting the stress response of normal erythroid cells. Impairment of this function in JAK2V617F-positive erythroid cells maintains EPO-R (show EPOR ELISA Kits) signaling in proliferation mode, contributing to erythrocytosis in PV.

  2. Mannan-binding lectin (MBL (show MBL2 ELISA Kits)) bound to T cells through interaction between the collagen-like region of MBL (show MBL2 ELISA Kits) and calreticulin (CRT (show CALR ELISA Kits)) expressed on the T-cell surface.

  3. CRT exposure represents a novel powerful prognostic biomarker for patients with acute myeloid leukemia (show BCL11A ELISA Kits).

  4. In absence of CALR (show CALR ELISA Kits), immature MPO (show MPO ELISA Kits) protein precursors are degraded in the proteasome.

  5. In patients with HD, a panel using calretinin and peripherin with or without MAP-2 may be most helpful in identifying transition zones

  6. Coexisting mutations of the JAK2 (show JAK2 ELISA Kits), CALR (show CALR ELISA Kits), and MPL (show MPL ELISA Kits) genes in myeloproliferative neoplasms suggest that CALR (show CALR ELISA Kits) and MPL (show MPL ELISA Kits) should be analyzed not only in JAK2 (show JAK2 ELISA Kits)-negative patients but also in low V617F mutation patients.

  7. CALR (show CALR ELISA Kits)-mutated essential thrombocythemia (ET) patients harbored a higher mutant load at progenitor level than JAK2V617F-positive ET (HSCs: 39.9% vs 7.5% p<0.001, hematopoietic stem cells)

  8. Results indicate that NGF (show NGFB ELISA Kits) inhibited CRT translocation induced by mitoxantrone. NGF (show NGFB ELISA Kits) effect on CRT translocation could have consequences in immunotherapy, potentially lessening the effectiveness of this type of treatment.

  9. The consistent association between Calr (show CALR ELISA Kits) and Dio2 (show DIO2 ELISA Kits) expression suggests that enhanced expression of these two genes facilitate detrimental effects on cartilage integrity.

  10. The myeloproliferative neoplasms (MPNs) patients carrying Calreticulin(CALR (show CALR ELISA Kits)) mutations presented with higher platelet counts and lower hemoglobin (show HBB ELISA Kits) levels compared to those with mutated JAK2 (show JAK2 ELISA Kits). However, all of the leukemia patients had negative results for CALR (show CALR ELISA Kits) mutations.

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. study provides a model showing that the C-terminal of mutant CALR (show CALR ELISA Kits) activated JAK (show JAK3 ELISA Kits)-STAT (show STAT1 ELISA Kits) signaling specifically downstream of MPL (show MPL ELISA Kits) and may have a central role in CALR (show CALR ELISA Kits)-induced myeloproliferative neoplasms

  2. the results of this investigation provide the first molecular insights into the phospholipid binding site of calreticulin (show CALR ELISA Kits) as a key anchor point for the cell surface expression of calreticulin (show CALR ELISA Kits) on apoptotic cells

  3. a profound impairment in calreticulin (show CALR ELISA Kits) function when its lectin site was inactivated. Remarkably, inactivation of the polypeptide binding site had little impact. These findings indicate that the lectin-based mode of client interaction is the predominant contributor to the chaperone functions of calreticulin (show CALR ELISA Kits) within the endoplasmic reticulum.

  4. This essential role of calreticulin (show CALR ELISA Kits) in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  5. Study provides evidence that chronic stress activates calreticulin (show CALR ELISA Kits) and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  6. This study for the first time revealed that increased CRT inhibited Fas (show FAS ELISA Kits)/FasL (show FASL ELISA Kits)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  7. The findings highlight the importance of CALR (show CALR ELISA Kits) in female reproduction and demonstrate that compromised CALR (show CALR ELISA Kits) function leads to ovarian insufficiency and female infertility.

  8. Calreticulin (show CALR ELISA Kits) mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  9. CALR (show CALR ELISA Kits) mutants are sufficient to induce thrombocytosis through MPL (show MPL ELISA Kits) activation.

  10. Thrombopoietin receptor (show MPL ELISA Kits) activation by myeloproliferative neoplasm associated calreticulin (show CALR ELISA Kits) mutants.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. GSK3ss down-regulates the creatine transporter CreaT, an effect reversed by treatment with the antidepressant Lithium and by co-expression of PKB/Akt (show AKT1 ELISA Kits).

  2. Mammalian target of rapamycin (mTOR (show FRAP1 ELISA Kits)) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1 (show SGK1 ELISA Kits).

  3. The observations suggest that SGK1 (show SGK1 ELISA Kits) regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve (show PIKFYVE ELISA Kits).

SLC6A8 Antigen Profile

Antigen Summary

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC6A8

  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (slc6a8) Elisa Kit
  • calreticulin (CALR) Elisa Kit
  • calreticulin (Calr) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (Slc6a8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter), member 8 (SLC6A8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8) Elisa Kit
  • AA589632 Elisa Kit
  • Calregulin Elisa Kit
  • cC1qR Elisa Kit
  • CCDS1 Elisa Kit
  • CHOT1 Elisa Kit
  • CHT1 Elisa Kit
  • Creat Elisa Kit
  • CRT Elisa Kit
  • CRTR Elisa Kit
  • CT1 Elisa Kit
  • RO Elisa Kit
  • SLC6A8 Elisa Kit
  • SSA Elisa Kit

Protein level used designations for SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , Sodium- and chloride-dependent creatine transporter 1 , ct1 , sodium- and chloride-dependent creatine transporter 1-like , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , sodium- and chloride-dependent creatine transporter 1 , CT1 , choline transporter , creatine transporter 1 , solute carrier family 6 member 8 , creatine transporter, solute carrier family 6, member 8 , solute carrier family 6, member 8 , creatine transporter SLC6A8

473853 Pan troglodytes
567544 Danio rerio
698307 Macaca mulatta
100127575 Xenopus (Silurana) tropicalis
100404520 Callithrix jacchus
100440816 Pongo abelii
100589275 Nomascus leucogenys
811 Homo sapiens
12317 Mus musculus
492242 Canis lupus familiaris
100302506 Sus scrofa
282367 Bos taurus
100009280 Oryctolagus cuniculus
102857 Mus musculus
6535 Homo sapiens
50690 Rattus norvegicus
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