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Browse our SLC6A8 (SLC6A8) ELISA Kits

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Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 ELISA Kits (SLC6A8)
On www.antibodies-online.com are 15 Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) ELISA Kits from 6 different suppliers available. Additionally we are shipping SLC6A8 Antibodies (41) and SLC6A8 Proteins (4) and many more products for this protein. A total of 67 SLC6A8 products are currently listed.
Synonyms:
AA589632, Calregulin, cC1qR, CCDS1, CHOT1, CHT1, Creat, CRT, CRTR, CT1, RO, SLC6A8, SSA
list all ELISA KIts Gene Name GeneID UniProt
SLC6A8 811 P27797
SLC6A8 12317 P14211
SLC6A8 50690 P28570

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SLC6A8 (SLC6A8) ELISA Kits by Reactivity

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Top referenced SLC6A8 ELISA Kits

  1. Human SLC6A8 ELISA Kit for Sandwich ELISA - ABIN414440 : Gkaliagkousi, Gavriilaki, Nikolaidou, Chatzopoulou, Anyfanti, Triantafyllou, Petidis, Zamboulis, Douma: Association between cardiotrophin 1 levels and central blood pressure in untreated patients with essential hypertension. in American journal of hypertension 2014 (PubMed)
    Show all 3 references for ABIN414440

  2. Rat (Rattus) SLC6A8 ELISA Kit for Sandwich ELISA - ABIN416125 : Chen, Hsieh, Peng, Peng: Exercise rescued chronic kidney disease by attenuating cardiac hypertrophy through the cardiotrophin-1 -> LIFR/gp 130 -> JAK/STAT3 pathway. in European journal of preventive cardiology 2014 (PubMed)
    Show all 2 references for ABIN416125

More ELISA Kits for SLC6A8 Interaction Partners

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. Alterated IQGAP1 (show IQGAP1 ELISA Kits)/Rho GTPase (show RACGAP1 ELISA Kits) signaling in myeloproliferative neoplasm erythrocytes is dependent on JAK2 (show JAK2 ELISA Kits)/CALR (show CALR ELISA Kits) mutational status.

  2. Recurrent somatic mutations in calreticulin (CALR (show CALR ELISA Kits)) gene that encodes a molecular chaperone (show HSP90AA1 ELISA Kits) residing in the endoplasmic reticulum were identified in 2013 in a subset of patients with myeloproliferative neoplasms (MPNs).

  3. These results indicate that mutant CALR (show CALR ELISA Kits) causes myeloproliferation because of the activation of JAK (show JAK3 ELISA Kits)-STAT (show STAT1 ELISA Kits) pathway and not by the inhibition of phagocytosis, which is similar to the myeloproliferation caused by JAK2 (show JAK2 ELISA Kits) V617F mutation.

  4. our studies demonstrate that occasional patients with CALR (show CALR ELISA Kits) mutation-positive ET or MF carry other MPN (show PRSS27 ELISA Kits)-initiating genetic mutations (including JAK2 (show JAK2 ELISA Kits) V617F), acquire "secondary mutations" before or after the CALR (show CALR ELISA Kits) mutation, or evolve over time to being CALR (show CALR ELISA Kits) mutation-homozygous.

  5. The meta-analysis of the different populations (including Asian, European, North American and Australian) showed that CALR (show CALR ELISA Kits) mutation may increase the prevalence of patients with essential thrombocythemia (19%) and primary myelofibrosis (22%).

  6. CALR (show CALR ELISA Kits)- and JAK2 (show JAK2 ELISA Kits)-mutated MPNs are broadly similar in terms of the quantity, frequency and spectrum of co-occurring mutations and therefore observed biological differences are likely to not be heavily influenced by the nature and quantity of co-mutated genes.

  7. The family with JAK2 (show JAK2 ELISA Kits) G571S mutations reported here teaches us that 1 germline JAK2 (show JAK2 ELISA Kits) mutation may hide a somatic CALR (show CALR ELISA Kits) mutation, and that, in this case, the phenotype (thrombocytosis) and disease (essential thrombocythemia [ET]) are likely due to the somatic CALR (show CALR ELISA Kits) mutation. This highlights the complexity of making the diagnosis of ET (vs. HT) in a familial context.

  8. From included 1138 patients vascular risk patients, 18 individuals were tested positive for the JAK2 (show JAK2 ELISA Kits) V617F mutation. CALR (show CALR ELISA Kits) exon 9 mutations were not detected in any of our patients. CALR (show CALR ELISA Kits) exon 9 mutations are infrequent in vascular risk patients.

  9. CALR (show CALR ELISA Kits) mutations are rarely involved in myelodysplastic syndromes with myelofibrosis

  10. Genotyping for CALR (show CALR ELISA Kits) could be a useful diagnostic tool for JAK2 (show JAK2 ELISA Kits)/MPL (show MPL ELISA Kits)-negative ET, since the data suggest that CALR (show CALR ELISA Kits) is much more prevalent than MPL (show MPL ELISA Kits), therefore testing for CALR (show CALR ELISA Kits) should be considered in patients who are JAK2 (show JAK2 ELISA Kits) negative as its frequency is almost 20 times that of MPL (show MPL ELISA Kits) mutation.

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. a profound impairment in calreticulin (show CALR ELISA Kits) function when its lectin site was inactivated. Remarkably, inactivation of the polypeptide binding site had little impact. These findings indicate that the lectin-based mode of client interaction is the predominant contributor to the chaperone functions of calreticulin (show CALR ELISA Kits) within the endoplasmic reticulum.

  2. This essential role of calreticulin (show CALR ELISA Kits) in nucleocytoplasmic communication competency ties its regulatory action with proficiency of cardiac myofibrillogenesis essential for proper cardiac development.

  3. Study provides evidence that chronic stress activates calreticulin (show CALR ELISA Kits) and might be one of the pathological mechanisms underlying the motor coordination and motor learning dysfunctions seen in social defeat mice.

  4. This study for the first time revealed that increased CRT inhibited Fas (show FAS ELISA Kits)/FasL (show FASL ELISA Kits)-mediated neuronal cell apoptosis during the early stage of ischemic stroke, suggesting it to be a potential protector activated soon after ischemia-reperfusion injury

  5. The findings highlight the importance of CALR (show CALR ELISA Kits) in female reproduction and demonstrate that compromised CALR (show CALR ELISA Kits) function leads to ovarian insufficiency and female infertility.

  6. Calreticulin (show CALR ELISA Kits) mediates vascular smooth muscle cell responses to injury through the regulation of collagen deposition and neointima formation.

  7. CALR (show CALR ELISA Kits) mutants are sufficient to induce thrombocytosis through MPL (show MPL ELISA Kits) activation.

  8. Thrombopoietin receptor (show MPL ELISA Kits) activation by myeloproliferative neoplasm associated calreticulin (show CALR ELISA Kits) mutants.

  9. These studies reveal central roles for ATP and calcium binding as regulators of calreticulin (show CALR ELISA Kits)-substrate interactions and as key determinants of PLC (show HSPG2 ELISA Kits) dynamics.

  10. study demonstrates for the first time that LRH-1 (show NR5A2 ELISA Kits) has a CRT-dependent NES (show NES ELISA Kits) which is not only required for cytoplasmic trafficking, but also essential for correct protein folding to avoid misfolding-induced aggregation.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Creatine), Member 8 (SLC6A8) interaction partners

  1. GSK3ss down-regulates the creatine transporter CreaT, an effect reversed by treatment with the antidepressant Lithium and by co-expression of PKB/Akt (show AKT1 ELISA Kits).

  2. Mammalian target of rapamycin (mTOR (show FRAP1 ELISA Kits)) stimulates the creatine transporter SLC6A8 through mechanisms at least partially shared by the serum and glucocorticoid-inducible kinase SGK1 (show SGK1 ELISA Kits).

  3. The observations suggest that SGK1 (show SGK1 ELISA Kits) regulates the creatine transporter SLC6A8 at least partially through phosphorylation and activation of PIKfyve (show PIKFYVE ELISA Kits).

SLC6A8 Antigen Profile

Antigen Summary

The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SLC6A8

  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (SLC6A8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (slc6a8) Elisa Kit
  • calreticulin (CALR) Elisa Kit
  • calreticulin (Calr) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter, creatine), member 8 (Slc6a8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter), member 8 (SLC6A8) Elisa Kit
  • solute carrier family 6 (neurotransmitter transporter), member 8 (Slc6a8) Elisa Kit
  • AA589632 Elisa Kit
  • Calregulin Elisa Kit
  • cC1qR Elisa Kit
  • CCDS1 Elisa Kit
  • CHOT1 Elisa Kit
  • CHT1 Elisa Kit
  • Creat Elisa Kit
  • CRT Elisa Kit
  • CRTR Elisa Kit
  • CT1 Elisa Kit
  • RO Elisa Kit
  • SLC6A8 Elisa Kit
  • SSA Elisa Kit

Protein level used designations for SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8 , Sodium- and chloride-dependent creatine transporter 1 , ct1 , sodium- and chloride-dependent creatine transporter 1-like , CRP55 , ERp60 , HACBP , Sicca syndrome antigen A (autoantigen Ro; calreticulin) , calregulin , endoplasmic reticulum resident protein 60 , grp60 , sodium- and chloride-dependent creatine transporter 1 , CT1 , choline transporter , creatine transporter 1 , solute carrier family 6 member 8 , creatine transporter, solute carrier family 6, member 8 , solute carrier family 6, member 8 , creatine transporter SLC6A8

GENE ID SPECIES
473853 Pan troglodytes
567544 Danio rerio
698307 Macaca mulatta
100127575 Xenopus (Silurana) tropicalis
100404520 Callithrix jacchus
100440816 Pongo abelii
100589275 Nomascus leucogenys
811 Homo sapiens
12317 Mus musculus
492242 Canis lupus familiaris
100302506 Sus scrofa
282367 Bos taurus
100009280 Oryctolagus cuniculus
102857 Mus musculus
6535 Homo sapiens
50690 Rattus norvegicus
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