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Eukaryotic Translation Initiation Factor 2 Subunit 1 ELISA Kits (EIF2S1)
On www.antibodies-online.com are 1 Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) ELISA Kits from 1 different suppliers available. Additionally we are shipping EIF2S1 Antibodies (133) and EIF2S1 Proteins (19) and many more products for this protein. A total of 161 EIF2S1 products are currently listed.
Synonyms:
35kDa, 0910001O23Rik, 2410026C18Rik, CG9946, deIF2alpha, Dmel\\CG9946, EIF-2, eIF-2 a, eIF-2 alpha, EIF-2A, EIF-2alpha, EIF2, eIF2 alpha, eIF2-alpha, EIF2A, eIF2alpha, eif2s1, elF2alpha, fb19d01, IF2A_DROME, l(1)14Cf, l(1)19-153, M(1)8e3-10, M(1)14C, M(1)19-153, wu:fb19d01
list all ELISA KIts Gene Name GeneID UniProt
EIF2S1 13665 Q6ZWX6
EIF2S1 54318 P68101
EIF2S1 1965 P05198

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EIF2S1 (EIF2S1) ELISA Kits by Reactivity

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Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Therapeutic modulation of eIF2alpha phosphorylation rescues TDP-43 (show TARDBP ELISA Kits) toxicity in amyotrophic lateral sclerosis disease models.

Mouse (Murine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. ER stress-induced increase in ATF4 (show ATF4 ELISA Kits) and CHOP (show DDIT3 ELISA Kits) expression is initiated by an increase in Atf4 (show ATF4 ELISA Kits) and Chop (show DDIT3 ELISA Kits) mRNA, which is also dependent upon eIF2alpha (show EIF2A ELISA Kits) phosphorylation.

  2. Data indicate that 5xFAD-related pathologies do not necessarily require hyperphosphorylation of eIF2alpha (show EIF2A ELISA Kits) to emerge.

  3. Endoplasmic reticulum stress suppressed CReP (show PPP1R15B ELISA Kits) expression in an IRE1 alpha (show ERN1 ELISA Kits)-dependent manner, which increased eIF2alpha (show EIF2A ELISA Kits) phosphorylation and consequently attenuated protein synthesis.

  4. eIF2alphaP acts as a molecular switch that dictates either cell survival or death by activated Akt (show AKT1 ELISA Kits) in response to oxidative stress.

  5. aberrant phosphorylation of eukaryotic initiation factor (show EIF4G1 ELISA Kits)-2a (eIF2a (show EIF2A ELISA Kits)) may induce synaptic failure and neurodegeneration through persistent translational inhibition of global protein synthesis.

  6. Alteration of protein homeostasis and eIF2alpha (show EIF2A ELISA Kits) phosphorylation status by pathogenic huntingtin (show HTT ELISA Kits) appears to be an important cause of striatal cell death.

  7. Data indicate that prolonged endoplasmic reticulum stress inhibits protein synthesis independently of translation initiation factor eIF2alpha (show EIF2A ELISA Kits)-P.

  8. This study demonistrated that Genetic deletion of eIF2alpha (show EIF2A ELISA Kits) kinase PERK (show EIF2AK3 ELISA Kits) prevented enhanced phosphorylation of eIF2alpha (show EIF2A ELISA Kits) and deficits in protein synthesis, synaptic plasticity and spatial memory in animal disease model of Alzheimer's disease.

  9. eIF2alpha (show EIF2A ELISA Kits) phosphorylation in the context of the ER stress response plays a role in cell survival by counteracting the p53 (show TP53 ELISA Kits)-mediated mitochondrial apoptosis in response to statins.

  10. eIF2a (show EIF2A ELISA Kits) is hyperphosphorylated in the cortex of aged mice. Young human-ApoE4 targeted-replacement mice show increased p-eIF2a/eIF2a (show EIF2A ELISA Kits) levels in both cortex and hippocampus.

Pig (Porcine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. In conclusion, the immediate-early (show JUN ELISA Kits) IE180 protein of pseudorabies virus has the previously uncharacterized ability to suppress phosphorylation levels of the eukaryotic translation initiation factor (show EIF2A ELISA Kits) eIF2alpha (show EIF2A ELISA Kits).

Human Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. These data indicate that PERK (show EIF2AK3 ELISA Kits) regulates radioresistance in oropharyngeal carcinoma through NF-kB activation-mediated phosphorylation of eIF2alpha (show EIF2A ELISA Kits)

  2. The stem-loop of noncoding RNA 886 is structural feature not only critical for inhibiting PKR (show PKLR ELISA Kits) autophosphorylation, but also the phosphorylation of its cellular substrate, EIF-2alpha.

  3. overexpression of eIF5 (show EIF5 ELISA Kits) and 5MP induces translation of ATF4 (show ATF4 ELISA Kits).

  4. Through pathway analysis it was suggested the involvement of eIF2 and mTOR (show FRAP1 ELISA Kits) in host cells upon Chlamydia trachomatis infection.

  5. PERK (show EIF2AK3 ELISA Kits)-eIF2alpha (show EIF2A ELISA Kits)-ATF4 (show ATF4 ELISA Kits) signaling pathway mediated by endoplasmic reticulum stress involved in osteoblast differentiation of periodontal ligament cells under cyclic mechanical force.

  6. EnR (show LARGE ELISA Kits) stress assessed by expression of PERK (show EIF2AK3 ELISA Kits) and p-eIF2alpha (show EIF2A ELISA Kits) was significantly associated with tumor infiltrating lymphocytes (TILs) in HER2 (show ERBB2 ELISA Kits)-positive breast cancer.

  7. we unravels a new miRs-based mechanism that helps maintain intracellular proteostasis and promote cell survival during ER stress through upregulation of miR (show MLXIP ELISA Kits)-30b-5p and miR (show MLXIP ELISA Kits)-30c-5p which target eIF2alpha (show EIF2A ELISA Kits) and thereby inhibit the p-eIF2alpha (show EIF2A ELISA Kits)/ATF4 (show ATF4 ELISA Kits)/CHOP (show DDIT3 ELISA Kits) pro-apoptotic pathway, identifying miR (show MLXIP ELISA Kits)-30b-5p and miR (show MLXIP ELISA Kits)-30c-5p as potentially new targets for anti-cancer therapies.

  8. Our work suggests that OLA1 (show OLA1 ELISA Kits) is a novel translational GTPase (show RACGAP1 ELISA Kits) and plays a suppressive role in translation and cell survival, as well as cancer growth and progression.

  9. a delay in eIF2-bound GTP (show AK3 ELISA Kits) hydrolysis should occur. In this work, we reconstructed this situation and found that such a delay leads to the redistribution of initiation complexes in favor to downstream AUG codons.

  10. The reactive oxygen species-generating NADPH oxidase-4 (Nox4 (show NOX4 ELISA Kits)) is induced downstream of ATF4 (show ATF4 ELISA Kits), binds to a PP1 (show PPA1 ELISA Kits)-targeting subunit GADD34 (show PPP1R15A ELISA Kits) at the endoplasmic reticulum, and inhibits PP1 (show PPA1 ELISA Kits) activity to increase eIF2alpha (show EIF2A ELISA Kits) phosphorylation and ATF4 (show ATF4 ELISA Kits) levels.

Cow (Bovine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Caspase (show CASP3 ELISA Kits)(s)-dependent proteolysis of molecular chaperones and eIF2alpha (show EIF2A ELISA Kits) may be novel signaling pathways of apoptosis.

EIF2S1 Antigen Profile

Antigen Summary

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2\; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3\; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987

Alternative names and synonyms associated with EIF2S1

  • eukaryotic translation Initiation Factor 2alpha (eIF-2alpha) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (eif2s1) Elisa Kit
  • eukaryotic translation initiation factor 2 alpha subunit (LOC693063) Elisa Kit
  • eukaryotic translation initiation factor 2 alpha subunit (CNI00230) Elisa Kit
  • eukaryotic translation initiation factor 2 alpha subunit (THAPSDRAFT_105) Elisa Kit
  • Eukaryotic translation initiation factor 2 subunit 1 (if2a) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100339093) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100350462) Elisa Kit
  • eukaryotic translation initiation factor 2 subunit 1 (if2a) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha (LOC100155472) Elisa Kit
  • eukaryotic translation initiation factor 2, subunit 1 alpha b (eif2s1b) Elisa Kit
  • 35kDa Elisa Kit
  • 0910001O23Rik Elisa Kit
  • 2410026C18Rik Elisa Kit
  • CG9946 Elisa Kit
  • deIF2alpha Elisa Kit
  • Dmel\\CG9946 Elisa Kit
  • EIF-2 Elisa Kit
  • eIF-2 a Elisa Kit
  • eIF-2 alpha Elisa Kit
  • EIF-2A Elisa Kit
  • EIF-2alpha Elisa Kit
  • EIF2 Elisa Kit
  • eIF2 alpha Elisa Kit
  • eIF2-alpha Elisa Kit
  • EIF2A Elisa Kit
  • eIF2alpha Elisa Kit
  • eif2s1 Elisa Kit
  • elF2alpha Elisa Kit
  • fb19d01 Elisa Kit
  • IF2A_DROME Elisa Kit
  • l(1)14Cf Elisa Kit
  • l(1)19-153 Elisa Kit
  • M(1)8e3-10 Elisa Kit
  • M(1)14C Elisa Kit
  • M(1)19-153 Elisa Kit
  • wu:fb19d01 Elisa Kit

Protein level used designations for EIF2S1

CG9946-PA , eIF-2alpha-PA , eukaryotic initiation factor 2alpha , eukaryotic translation initiation factor 2 , eukaryotic translation initiation factor 2alpha , minute (1) 14C , EIF-2A , EIF-2alpha , eIF-2-alpha , eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2 subunit alpha , eukaryotic translation initiation factor 2 alpha subunit , Eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa , eIF-2A , eIF-2alpha , eukaryotic translation initiation factor 2A , eIF2 alpha subunit , eukaryotic translation initiation factor 2, subunit 1 (alpha )

GENE ID SPECIES
32617 Drosophila melanogaster
448087 Xenopus (Silurana) tropicalis
693063 Bombyx mori
3259501 Cryptococcus neoformans var. neoformans JEC21
7449310 Thalassiosira pseudonana CCMP1335
100195154 Salmo salar
100339093 Oryctolagus cuniculus
100350462 Oryctolagus cuniculus
100528138 Ictalurus punctatus
100587728 Nomascus leucogenys
13665 Mus musculus
54318 Rattus norvegicus
100155472 Sus scrofa
321564 Danio rerio
1965 Homo sapiens
380444 Xenopus laevis
423279 Gallus gallus
480361 Canis lupus familiaris
327694 Bos taurus
100174029 Pongo abelii
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